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FDA designates AMT-080 gene therapy for Duchenne muscular dystrophy

Amsterdam Molecular Therapeutics (AMT) Holding N.V. a leader in the field of human gene therapy, announced today that the U.S. Food and Drug Administration (FDA) has designated AMT-080, a gene therapy for Duchenne muscular dystrophy (DMD) as an orphan drug.

24 Sep 2010

Belfer Institute, sanofi-aventis collaborate to discover anticancer drugs

Dana-Farber Cancer Institute's Belfer Institute of Applied Cancer Science (Belfer Institute) and sanofi-aventis announced today that they have entered into a collaboration and license option agreement to identify and validate novel oncology targets for further discovery and development by sanofi-aventis of novel therapeutics agents directed to such targets and related biomarkers.

24 Sep 2010

NCCN launches series of guidelines on cancer treatment

Patients with cancer and their caregivers have a new resource to help them navigate the maze of treatment options that they often confront. Today at the NCCN Patient Advocacy Summit in Washington D.C., the National Comprehensive Cancer Network launched its new series of NCCN Guidelines for Patients, consumer-friendly translations of the NCCN Clinical Practice Guidelines in Oncology outlining appropriate cancer treatment.

24 Sep 2010

TAVI procedure reduces mortality rate in patients with aortic stenosis

Just released data from a clinical trial shows promise for a new minimally invasive treatment option for patients with severe aortic stenosis who are too sick for traditional forms of open-heart surgery. As compared to standard medical therapy, the new procedure, transcatheter aortic valve implantation (TAVI), significantly reduced mortality rates in patients who received the new valve.

24 Sep 2010

Cianna Medical launches SAVI Sisters program to educate about breast cancer treatment options

Cianna Medical, Inc., the maker of the SAVI breast brachytherapy applicator, today announced the launch of SAVI Sisters, a program designed to provide education about breast cancer treatment options, primarily through social networking.

24 Sep 2010

CIC proposes criteria to improve endpoints for cancer immunotherapy trials

The Cancer Research Institute (CRI) Cancer Immunotherapy Consortium (CIC), the leading global initiative in advancing the emerging field of immuno-oncology, has proposed criteria for improved endpoints for cancer immunotherapy trials, which were published online on September 8 in the Journal of the National Cancer Institute.

24 Sep 2010

CAP meeting to highlight medical diagnostic procedures

New science in cancer, genetic testing, molecular diagnostics, medical ethics, and gender-based disorders will be featured topics when nearly 1,200 pathologists gather at the Hyatt Regency Chicago on September 26 - 29 for the annual scientific meeting of the College of American Pathologists (CAP).

24 Sep 2010

Kids with preexisting illness get new protection for coverage but hurdles remain

When an insurance company refused to cover Deborah Gustlin's son because he has Asperger's syndrome, she took a drastic step 'I decided to lie,' says the 51-year-old resident of Morgan Hill, Calif.

24 Sep 2010

Immune-mediated disturbances of neurons contribute to MS: Research

Researchers in Germany have gained new insight into how the immune system causes damage associated with multiple sclerosis (MS), an incurable neuroinflammatory disorder.

24 Sep 2010

Asthma linked to seven genetic variants: Study

In a new study seven genes linked to asthma have been discovered. For the research genetic variations of 10,365 people with asthma and 16,110 people without the condition was studied. The variants identified showed an association with childhood asthma and some were also associated with later-onset asthma.

24 Sep 2010

FDA grants clearance for HPβCD treatment for Niemann Pick Type C disease

Children's Hospital & Research Center Oakland announced today that the US Food and Drug Administration (FDA) has granted clearance of an Investigational New Drug (IND) application to introduce Trappsol Cyclo (Hydroxypropyl Beta Cyclodextrin or HPβCD) into the brains of six year old identical twin girls dying of a rare brain-destroying cholesterol disease called Niemann Pick Type C (NPC).

24 Sep 2010

Advanced Targeting Systems receives NCI award to advance SP-SAP drug

Advanced Targeting Systems, the company that pioneered the targeting of specific cell types to manipulate them for the treatment of diseases and for research into the function of biological systems, has been awarded $3 million from the National Cancer Institute (NCI).

24 Sep 2010

Lutonix presents data on Moxy Drug Coated Balloon Catheter at TCT meeting

Lutonix, Inc., headquartered in Minneapolis, MN, today announced six-month data from three separate drug coated balloon studies presented at the TransCatheter Therapeutics (TCT) meeting this week demonstrated the ability of the Moxy Drug Coated Balloon Catheter to inhibit restenosis in both peripheral and coronary arteries.

24 Sep 2010

Researchers report MALAT1 gene regulates pre-mRNA splicing in cancer

Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing a critical step in the earliest stage of protein production. Their study appears in the journal Molecular Cell.

24 Sep 2010

Researchers to develop vitamin D producing fluorescent lamp for fat malabsorption syndromes

Boston University School of Medicine (BUSM) researchers have been awarded a Small Business Technology Transfer (STTR) phase 1 award to develop and test a newly designed fluorescent lamp that is capable of producing vitamin D in the skin.

24 Sep 2010

Abbott, Reata enter agreement to commercialize bardoxolone drug for CKD

Abbott and Reata Pharmaceuticals today announced that they have entered into a collaboration agreement to develop and commercialize bardoxolone methyl (bardoxolone), which is currently in late Phase 2 trials for the treatment of chronic kidney disease (CKD).

24 Sep 2010