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Amgen granted FDA priority review designation for denosumab BLA

Amgen today announced that the U.S. Food and Drug Administration (FDA) has granted priority review designation to denosumab, a subcutaneous RANK Ligand inhibitor, for the treatment of bone metastases to reduce skeletal related events (SREs) in patients with cancer.

17 Jul 2010

Researchers discover potential way to stop tumor growth

Washington State University researchers have discovered a way to help cancer cells age and die, creating a promising avenue for slowing and even stopping the growth of tumors. "Hopefully, we can make cancer cells die like normal cells," says Weihang Chai, an assistant professor in the WSU School of Molecular Biosciences and WWAMI medical education program in Spokane. "Basically, you make the cancer cell go from immortal to mortal."

17 Jul 2010

Impact of circadian dysregulation on mental, physical health

Circadian (daily) rhythms are found in all functions - e.g. performance, mood, endocrine rhythms, behaviour, sleep timing. The biological clocks that control circadian rhythms are based on a genetic programme of interacting molecules in cells throughout the body, coordinated by a ´master clock´ in the brain and synchronised by external cues, mainly light.

16 Jul 2010

Largest effort to find gene-environment interactions underlying schizophrenia risk

At the 23rd ECNP Congress 2010 in Amsterdam, Professor Dr. Jim van Os, Chairman of the Department of Psychiatry and Neuropsychology at Maastricht University Medical Centre, The Netherlands, will present the EU-GEI project, involving more than 7,500 patients and their families, which brings together a multidisciplinary research team from 15 countries in the largest effort to date to find gene-environment interactions underlying schizophrenia risk.

16 Jul 2010

Report identifies gaps in research for 20 suspected carcinogens

A new report from the American Cancer Society and other world-leading health groups identifies gaps in research for 20 suspected carcinogens whose potential to cause cancer is as yet unresolved. The report is designed to prioritize agents for additional research, and to lead to well-planned epidemiologic or mechanistic studies leading to more definitive classification of these agents.

16 Jul 2010

National Trauma Institute launches 'Stop the Bleeding' awareness and giving campaign

The National Trauma Institute (NTI), a non-profit organization dedicated to funding trauma research in the United States, launched a powerful awareness and giving campaign in the heart of New York City today. While the images in the 15-second message may disturb some, trauma surgeon and NTI chairperson Dr. Timothy Fabian said, "We can't ignore the bloody truth—traumatic injury kills more than 170,000 people each year, not counting our soldiers overseas. Action is needed."

16 Jul 2010

Joint statement to help patients, physicians make informed decisions about use of rosiglitazone

The Endocrine Society, American Diabetes Association and American Association of Clinical Endocrinologists issue joint statement in response to an FDA panel's recommendation to keep rosiglitazone (Avandia) on the market

16 Jul 2010

Treatment admissions for abuse of prescription pain relievers increases by over 400%: Study

The proportion of all substance abuse treatment admissions of those aged 12 and older involving abuse of prescription pain relievers rose by over 400 percent from 2.2 percent in 1998 to 9.8 percent in 2008 according to a new study be the Substance Abuse and Mental Health Services Administration (SAMHSA). This dramatic rise in the proportion of admissions associated with the abuse of these drugs occurred among nearly all segments of the population regardless of age, gender, educational level and employment status.

16 Jul 2010

Active family engagement is important for recovery from substance abuse, chemical dependency

Active family engagement and commitment is one of the most underappreciated aspects of recovery from substance abuse and chemical dependency, according to clinical staff at Timberline Knolls Residential Treatment Center, a leading eating disorder and addiction treatment center.

16 Jul 2010

All dementia isn't Alzheimer's disease: Mayo Clinic

Occasional misplaced keys or forgotten names don't mark the beginning of dementia. All dementia isn't Alzheimer's disease. Some dementia symptoms can be reversed. Those facts and many more are covered in Deciphering Dementia, a supplemental Special Report to the July issue of Mayo Clinic Women's HealthSource

16 Jul 2010

Brain imaging studies can provide biomarkers for depression diagnosis: Study

Depression, known to be a condition with impaired psychosocial functioning that severely impacts the quality of life of patients and families, is actually defined with specific clinical symptoms such as sadness, difficulty to experience pleasure, sleep problems etc., present for at least two weeks. At least 40% of depressed patients actually benefit from an antidepressant treatment, whereas 20-30% of patients may suffer from chronic depression that negatively impacts their quality of life. In order to improve the efficiency of treatment and reduce the burden of depressive disorders, depression needs to be defined at the neurobiological level.

16 Jul 2010

$125,000 grant to study impact of delayed umbilical cord clamping on surgical outcomes

A newly funded study is set to determine whether waiting two minutes to clamp a newborn's umbilical cord after delivery could improve how well he or she recovers from corrective heart surgery.

16 Jul 2010

Researchers develop new strategy for treating multiple myeloma

Multiple myeloma is one of the most common blood cancers, and at present considered to be incurable. In a new study from Uppsala University, researchers now present a conceptually new model for the development and progression of multiple myeloma. The study was done in collaboration with Vrije Universitet Brussels and is published in the July edition of the on-line journal PLoS ONE.

16 Jul 2010

New research reports evaluating nephrology market in Europe released

BioTrends Research Group, Inc. has released two new syndicated market research reports evaluating the nephrology market in Europe. The reports, TreatmentTrends: Renal Anemia and TreatmentTrends: Bone and Mineral Metabolism, are derived from the responses of over 200 European nephrologists polled in May and June, 2010 regarding their approach to managing renal anemia and bone and mineral disturbances in their dialysis and chronic kidney disease patients.

16 Jul 2010

Two-thirds of world's population are vitamin D-insufficient or deficient

Vitamin D surfaces as a news topic every few months. How much daily vitamin D should a person get? Is it possible to have too much of it? Is exposure to the sun, which is the body's natural way of producing vitamin D, the best option? Or do supplements suffice?

16 Jul 2010

VIVUS disappointed with FDA Advisory Committee's vote on QNEXA for obesity treatment

VIVUS, Inc. today announced that the Endocrinologic and Metabolic Drugs Advisory Committee of the U.S. Food and Drug Administration (FDA) voted against the following question: "Based on the current available data, do you believe the overall benefit-risk assessment of PHEN/TPM (QNEXA) is favorable to support its approval for the treatment of obesity in individuals with a BMI > 30 kg/m2 or > 27 kg/m2 with weight-related co-morbidities?" The three co-morbidities included hypertension, diabetes and dyslipidemia.

16 Jul 2010

Study shows high rate of return to pre-injury level of function with arthroscopic treatment

Athletes who undergo arthroscopic surgery for a mechanical disorder of the hip have a good chance of being able to return to their sport at a high level of competition, according to a study that will be presented at the annual meeting of the American Orthopaedic Society for Sports Medicine, held July 15-18 in Providence, R.I. Almost 80 percent of patients were able to return to play after hip arthroscopy at an average of 9.4 months after surgery, and roughly 90 percent were able to return to the same level of competition.

16 Jul 2010

AAOS releases evidence-based clinical practice guideline for treating glenohumeral joint osteoarthritis

The American Academy of Orthopaedic Surgeons has approved and released an evidence-based clinical practice guideline on "The Treatment of Glenohumeral Joint Osteoarthritis." This major joint in the shoulder - the ball and socket joint - is sometimes affected by osteoarthritis, causing pain, loss of function, and reduced quality of life.

16 Jul 2010

Survival rates of nine types of cancer in Spain

Spanish epidemiologists have presented information on survival of nine types of cancer in Spain and have compared it with other European countries. At five years from diagnosis, the lowest survival rate is observed in lung cancer (less than 11%), and the highest in testicular cancer (95%). Cancer survival in Spain is at the European average.

16 Jul 2010

Steroid treatment can delay loss of kidney function

For patients with IgA nephropathy, a type of kidney disease, steroid treatment can prevent or delay loss of kidney function, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). IgA nephropathy is an autoimmune disease that affects the kidneys and a major cause of end-stage kidney failure in younger people

16 Jul 2010

Medical Condition News

Amgen granted FDA priority review designation for denosumab BLA

Researchers discover potential way to stop tumor growth

Impact of circadian dysregulation on mental, physical health

Largest effort to find gene-environment interactions underlying schizophrenia risk

Report identifies gaps in research for 20 suspected carcinogens

National Trauma Institute launches 'Stop the Bleeding' awareness and giving campaign

Joint statement to help patients, physicians make informed decisions about use of rosiglitazone

Treatment admissions for abuse of prescription pain relievers increases by over 400%: Study

Active family engagement is important for recovery from substance abuse, chemical dependency

All dementia isn't Alzheimer's disease: Mayo Clinic

Brain imaging studies can provide biomarkers for depression diagnosis: Study

$125,000 grant to study impact of delayed umbilical cord clamping on surgical outcomes

Researchers develop new strategy for treating multiple myeloma

New research reports evaluating nephrology market in Europe released

Two-thirds of world's population are vitamin D-insufficient or deficient

VIVUS disappointed with FDA Advisory Committee's vote on QNEXA for obesity treatment

Study shows high rate of return to pre-injury level of function with arthroscopic treatment

AAOS releases evidence-based clinical practice guideline for treating glenohumeral joint osteoarthritis

Survival rates of nine types of cancer in Spain

Steroid treatment can delay loss of kidney function

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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