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Biodel selects BIOD-105, BIOD-107 recombinant human insulin formulations for clinical testing, development

Biodel Inc. announced today that it has selected two new formulations of recombinant human insulin for clinical testing and is accelerating clinical development plans of these mealtime insulin drug candidates. The new formulations, BIOD-105 and BIOD-107, are designed to result in more rapid insulin action compared to currently marketed meal time insulin analogs while maintaining an injection site tolerability profile comparable to currently marketed insulins.

14 Mar 2011

KAI initiates enrollment in KAI-4169 Phase 2 study for secondary hyperparathyroidism

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced enrollment of the first patients in a Phase 2 study of KAI-4169, a novel pharmaceutical agent being tested for the treatment of secondary hyperparathyroidism (SHPT), which is a frequent and serious complication of end-stage renal disease (ESRD).

14 Mar 2011

Researchers discover new gene for Sensenbrenner syndrome

Dutch researchers of the Radboud University Medical Center in Nijmegen found a new gene for Sensenbrenner syndrome (Journal of Medical Genetics, 2011 Mar 4). The mutation adds support to the hypothesis that defects in ciliar transport are the cause of the disease. Project leader Dr. Heleen H. Arts is supported by a Kolff Junior Postdoc Grant of the Dutch Kidney Foundation.

14 Mar 2011

Transcept initiates enrollment in TO-2061 Phase 2 study for treatment resistant obsessive compulsive disorder

Transcept Pharmaceuticals, Inc. today announced the first patient has been enrolled in a Phase 2 clinical study to evaluate TO-2061 as an adjunctive treatment for obsessive compulsive disorder (OCD) in patients who have responded inadequately to currently approved treatments. OCD affects 1 to 2 percent of the United States adult population and can significantly impair the lives of patients and their families.

14 Mar 2011

European Patent Office grants ProtAffin key patent for CellJammer discovery technology

ProtAffin AG, a biotechnology company developing novel biopharmaceuticals for respiratory disease, inflammation and oncology, today announced that it has been granted a key patent by the European Patent Office protecting its CellJammer® discovery technology, which enables the development of a new class of biopharmaceuticals.

14 Mar 2011

Omthera commences dosing in pivotal Epanova Phase III EVOLVE trial in patients with very high triglycerides

Omthera Pharmaceuticals, Inc., a privately-held emerging specialty pharmaceuticals company, announced today that the first patient has been dosed in its pivotal Phase III EVOLVE (EpanoVa fOr Lowering Very high triglyceridEs) trial for Epanova™, the Company's lead compound for the treatment of patients with very high triglycerides. Epanova is an Omega-3 fatty acid containing a novel formulation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

14 Mar 2011

Anacor completes enrollment in AN2728 Phase 2b trial in psoriasis

Anacor Pharmaceuticals announced today that it has completed enrollment in its Phase 2b trial of AN2728, a topical anti-inflammatory product candidate for the treatment of psoriasis. Psoriasis is a chronic inflammatory skin disease that affects approximately 7.5 million people in the United States and over 100 million people worldwide.

14 Mar 2011

BioInvent commences BI-204 phase II study in patients with acute coronary syndrome

BioInvent International AB announces today the dosing of the first patient in the phase II study of the Company's antibody, BI-204. The product candidate is being developed for secondary prevention of cardiovascular events in patients with acute coronary syndrome.

14 Mar 2011

UCI's doctor, colleagues earn Kappa Delta Ann Doner Vaughan Award for osteosarcoma work

UC Irvine's Dr. Bang H. Hoang and colleagues have been presented the 2011 Kappa Delta Ann Doner Vaughan Award for their work advancing the understanding of how bone cancer spreads.

14 Mar 2011

Surgeons use stem cell technology for bone grafts to treat foot, ankle conditions

When patients need a bone graft for a foot or ankle surgery, bone often is taken from another part of their body. Now surgeons are using new methods to get bone material and even stem cells right "off the shelf," according to Glenn M. Weinraub, DPM, FACFAS, a California foot and ankle surgeon who is leading a discussion among surgeons on the next decade of bone healing at the American College of Foot and Ankle Surgeons' Annual Scientific Conference in Fort Lauderdale.

14 Mar 2011

Scientists discover cerebrospinal fluid proteins are essential for brain building

Proteins in fluids bathing the brain are essential for building the brain, discover scientists in a report published March 10 in the journal Neuron. The finding promises to advance research related to neurological disease, cancer and stem cells.

14 Mar 2011

CTI, Chroma enter agreement to co-develop and license tosedostat

Cell Therapeutics, Inc. and Chroma Therapeutics Ltd. announced today that the companies have entered into a co-development and license agreement providing CTI with exclusive marketing and co-development rights to Chroma's drug candidate tosedostat in North, Central and South America.

14 Mar 2011

New insights into factors affecting adolescent marijuana use

What factors are associated with a higher or lower risk of marijuana use among adolescents? There are some important differences for boys versus girls, according to a study in the March Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine.

14 Mar 2011

OICR welcomes Government of Canada's announcement of support for cancer control

Dr. Tom Hudson, President and Scientific Director of the Ontario Institute for Cancer Research today welcomed the Government of Canada's announcement of support for cancer control with a renewal of the mandate of the Canadian Partnership Against Cancer for five years and $250 million in funding.

14 Mar 2011

U-M's CoreValve trial to offer less invasive approach for patients with aortic stenosis

The University of Michigan Cardiovascular Center, a leader in heart valve replacement, will participate in a national clinical trial to offer patients a less invasive approach to replacing diseased aortic valves.

14 Mar 2011

Tamoxifen against breast cancer can save lives and reduce medical costs

Tamoxifen, taken by certain women as a preventive measure against breast cancer, saves lives and reduces medical costs. That is the conclusion of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

14 Mar 2011

Bad relationship with partner is the strongest predictor of maternal emotional distress

Pregnancy is meant to be a joyous time however some women experience overwhelming 'baby blues' before the birth of their child. Anxiety and depression during pregnancy can result in premature birth, or low birth weight, and impact the child's health even into early school years.

14 Mar 2011

Women with DCIS have excellent overall prognosis despite treatment

Women with ductal carcinoma in situ-DCIS-who later develop invasive breast cancer in the same breast are at higher risk of dying from breast cancer than those who do not develop invasive disease, according to a study published online March 11 in the Journal of the National Cancer Institute.

14 Mar 2011

EMP levels may help clinicians diagnose early emphysema

Monitoring blood for tiny particles released by cells lining the lungs may help clinicians diagnose emphysema in its earliest stages, according to researchers from Weill Cornell Medical College. The particles, called endothelial microparticles, are shed during the disease process as tiny blood vessels in the lungs, called pulmonary capillaries, are injured and die.

14 Mar 2011

HDL cholesterol structure finding could help explain cardioprotective effects

University of Cincinnati researchers have determined the structure of human HDL cholesterol and say the finding could help explain how this "fat packet" protects against cardiovascular diseases, including heart attack and stroke.

14 Mar 2011

Medical Condition News

Biodel selects BIOD-105, BIOD-107 recombinant human insulin formulations for clinical testing, development

KAI initiates enrollment in KAI-4169 Phase 2 study for secondary hyperparathyroidism

Researchers discover new gene for Sensenbrenner syndrome

Transcept initiates enrollment in TO-2061 Phase 2 study for treatment resistant obsessive compulsive disorder

European Patent Office grants ProtAffin key patent for CellJammer discovery technology

Omthera commences dosing in pivotal Epanova Phase III EVOLVE trial in patients with very high triglycerides

Anacor completes enrollment in AN2728 Phase 2b trial in psoriasis

BioInvent commences BI-204 phase II study in patients with acute coronary syndrome

UCI's doctor, colleagues earn Kappa Delta Ann Doner Vaughan Award for osteosarcoma work

Surgeons use stem cell technology for bone grafts to treat foot, ankle conditions

Scientists discover cerebrospinal fluid proteins are essential for brain building

CTI, Chroma enter agreement to co-develop and license tosedostat

New insights into factors affecting adolescent marijuana use

OICR welcomes Government of Canada's announcement of support for cancer control

U-M's CoreValve trial to offer less invasive approach for patients with aortic stenosis

Tamoxifen against breast cancer can save lives and reduce medical costs

Bad relationship with partner is the strongest predictor of maternal emotional distress

Women with DCIS have excellent overall prognosis despite treatment

EMP levels may help clinicians diagnose early emphysema

HDL cholesterol structure finding could help explain cardioprotective effects

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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