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Peripheral arterial disease increases cardiovascular disease risk: Study

Most patients don't suspect a thing, and yet they are seriously ill: hardening of the arteries - peripheral arterial disease PAD - doubles the risk of premature death and serious cardiovascular events such as heart attack and stroke.

31 Aug 2010

Study: IV ibuprofen decreases pain, morphine use in pre and post-operative orthopedic surgery patients

Cumberland Pharmaceuticals Inc. today announced the publication of new data supporting the safety and efficacy of Caldolor® (ibuprofen) Injection in pre and post-operative orthopedic surgery patients. The study, which was published in the August edition of the peer-reviewed journal Pain Medicine, concludes that IV ibuprofen significantly decreased pain and morphine use when compared with placebo.

31 Aug 2010

LESSON I trial provides evidence of benefits of everolimus-eluting stent over sirolimus-eluting stent

Results from the LESSON I trial presented today provide preliminary evidence for the therapeutic benefit of the newer generation everolimus-eluting stent over the previous gold standard, the early generation sirolimus-eluting stent. Moreover, LESSON I provides evidence that the formation of blood clots (stent thrombosis) - the principal shortcoming of early generation drug-eluting stents - may be diminished with the newer generation everolimus-eluting stent.

31 Aug 2010

Infants born by early elective C-section likely to have health problems: Study

Medical experts point to a disturbing trend of expectant mothers who are choosing to deliver their babies for non-medical reasons before 39 weeks of pregnancy.

31 Aug 2010

Using clopidogrel, PPIs increases cardiac damage risk: Study

Patients with coronary artery disease undergoing stent implantation are often prescribed the antiplatelet drug, clopidogrel. This drug prevents blood clots, but is known to have a side-effect that can cause stomach bleeding. Consequently, many users are also prescribed a proton pump inhibitor (PPI). Now, however, a meta-analysis of almost 160,000 patients carried out at the Medical University of Vienna and Wilhelminenhospital, Vienna, has shown that simultaneous use of these drugs can increase the risk of cardiac damage.

31 Aug 2010

Reduced heparin dose lowers bleeding risk after PCI without increasing risk of ischaemic complications

With both bleeding und thrombotic complications having a negative effect on PCI outcomes, increasing efforts have been made to improve PCI anticoagulation regimens. Although unfractionated heparin has been the standard anti-thrombotic agent in interventional cardiology for decades, there is still no solid evidence from large clinical trials to guide its dosing during PCI.

31 Aug 2010

Disruption of structural component in heart muscle cells occurs before decline in heart function

The disruption of a structural component in heart muscle cells, which is associated with heart failure, appears to occur even before heart function starts to decline, according to a new study by researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine.

31 Aug 2010

USAAC, HWCF enter partnership to support healthier lifestyle choices for young people

The U.S. Army Accessions Command (USAAC) and the Healthy Weight Commitment Foundation (HWCF) today announced a partnership aimed at countering the trend toward obesity among young people that could among other downsides diminish the pool of qualified young Americans available for military duty.

31 Aug 2010

Hospital admissions in Australia due to atrial fibrillation triples

A growing epidemic of the world's most common heart rhythm disorder is resulting in an alarming number of hospital admissions in Australia, according to cardiology researchers.

31 Aug 2010

Personal listening devices can impair hearing: Study

Personal listening devices like iPods have become increasingly popular among young and not so young people in recent years. But music played through headphones too loud or too long might pose a significant risk to hearing, according to a 24-year study of adolescent girls.

31 Aug 2010

African-Americans at higher risk of developing stent thrombosis

African-American race is a distinct risk factor for developing life-threatening blood clots after receiving a drug-coated stent, according to research reported in Circulation: Journal of the American Heart Association.

31 Aug 2010

Amsterdam Molecular first half 2010 net loss in line with last year

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, today reported its results for the first half year of 2010.

31 Aug 2010

SIR issues position statement to determine safety, effectiveness of interventional M.S. treatment

Recognizing that venous interventions may potentially play an important role in treating some patients who suffer from multiple sclerosis an incurable, disabling disease the Society of Interventional Radiology has issued a position statement indicating its support for high quality clinical research to determine the safety and effectiveness of interventional M.S. treatments.

31 Aug 2010

RXR-alpha protein helps to protect pigment cells from invasive melanoma: Research

New research on how skin cancer begins has identified adjacent cancer cells that scientists are calling "co-conspirators" in the genesis of melanoma, in findings that could someday hold the key to predicting, preventing and stopping this hard-to-treat cancer before it spreads.

31 Aug 2010

J-LANCELOT trial finds E5555 may reduce MACE without increasing serious bleeding events

Aspirin and thienopyridine antiplatelet therapy (such as clopidogrel) are standard care in the treatment of acute coronary syndrome (ACS) and even in stable coronary artery disease (CAD) after coronary intervention with stent. However, effective antiplatelet agents are needed which do not increase the risk of bleeding.

31 Aug 2010

Cell Therapy Foundation analysis calls for funding in medical research

Some of the most promising medical research conducted to treat diseases of the brain, heart, and circulatory system is moving too slowly to help millions of patients, according to the Cell Therapy Foundation, which advocates the use of adult stem cells to dramatically impact and improve the condition of patients who suffer from a variety of conditions.

31 Aug 2010

Antithrombotic therapy increases bleeding risk in CAD patients: Research

Antithrombotic therapy using antiplatelet and anticoagulant agents is the cornerstone of treatment for acute and chronic coronary artery disease (CAD), yet it is also associated with an increased risk of bleeding. It is paradoxical that elderly patients, the most likely population to develop CAD, are those that suffer most from bleeding complications.

31 Aug 2010

Tapentadol ER improves average intensity of chronic osteoarthritis knee pain: Study

Phase 3 safety and efficacy data comparing tapentadol extended release (ER) tablets, an investigational pain medication, to placebo in patients with moderate to severe chronic osteoarthritis knee pain have been published by Clinical Drug Investigation.

31 Aug 2010

Roche's MabThera continues to dwarf recently launched monoclonal antibodies: Report

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, for the treatment of non-Hodgkin's lymphoma and chronic lymphocytic leukemia, 41 percent of surveyed European hematologist-oncologists say that the favorable efficacy profile of Roche's MabThera (rituximab) is the most significant driver of their use of this brand, while 26 percent say MabThera's favorable risk-benefit profile is the most significant driver.

31 Aug 2010

FDA grants Priority Review status to Alimera Sciences' Iluvien for diabetic macular edema

Alimera Sciences, Inc.,, a biopharmaceutical company that specializes in the research, development and commercialization of prescription ophthalmic pharmaceuticals, announced today that the Company's New Drug Application (NDA) for Iluvien® (fluocinolone acetonide intravitreal insert) has been accepted for filing and granted Priority Review status by the U.S. Food and Drug Administration (FDA).

31 Aug 2010

Medical Condition News

Peripheral arterial disease increases cardiovascular disease risk: Study

Study: IV ibuprofen decreases pain, morphine use in pre and post-operative orthopedic surgery patients

LESSON I trial provides evidence of benefits of everolimus-eluting stent over sirolimus-eluting stent

Infants born by early elective C-section likely to have health problems: Study

Using clopidogrel, PPIs increases cardiac damage risk: Study

Reduced heparin dose lowers bleeding risk after PCI without increasing risk of ischaemic complications

Disruption of structural component in heart muscle cells occurs before decline in heart function

USAAC, HWCF enter partnership to support healthier lifestyle choices for young people

Hospital admissions in Australia due to atrial fibrillation triples

Personal listening devices can impair hearing: Study

African-Americans at higher risk of developing stent thrombosis

Amsterdam Molecular first half 2010 net loss in line with last year

SIR issues position statement to determine safety, effectiveness of interventional M.S. treatment

RXR-alpha protein helps to protect pigment cells from invasive melanoma: Research

J-LANCELOT trial finds E5555 may reduce MACE without increasing serious bleeding events

Cell Therapy Foundation analysis calls for funding in medical research

Antithrombotic therapy increases bleeding risk in CAD patients: Research

Tapentadol ER improves average intensity of chronic osteoarthritis knee pain: Study

Roche's MabThera continues to dwarf recently launched monoclonal antibodies: Report

FDA grants Priority Review status to Alimera Sciences' Iluvien for diabetic macular edema

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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