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New drug targets key mechanism in ALS, protects motor neurons

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS).

8 Feb 2024

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance."

8 Feb 2024

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

A new research perspective was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma."

8 Feb 2024

Enzyme released by immune cells may play role in depression

Mount Sinai researchers have shown for the first time that immune cells called monocytes, derived in the bone marrow and released into the bloodstream, can be drawn during stress into sites in the brain that control emotional behaviors.

8 Feb 2024

New immunotherapy borrows cancer's tricks to unleash powerful T cells

Immunotherapies using engineered T cells have ushered in a new era in cancer treatment, but they have their limits. They may cause side effects or stop working, and they do not work at all against 90% of cancers.

8 Feb 2024

Flat positioning may give stroke patients an edge before surgery

Positioning patients with large vessel ischemic (clot-caused) stroke with their heads flat (0-degrees) before surgery to remove the blood clot resulted in significant improvements in neurological function, compared to patients whose heads were elevated (at a 30-degree angle), according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

8 Feb 2024

NCCN publishes first-ever treatment recommendations pertaining to neuroblastoma

The National Comprehensive Cancer Network (NCCN) - an alliance of leading cancer centers - today published its first ever set of treatment recommendations pertaining to neuroblastoma.

8 Feb 2024

Study advances search for a blood test to identify disease-associated changes in the brain

Researchers in a Johns Hopkins Children's Center-led study that used genetic material from human blood and lab-grown brain cells say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.

8 Feb 2024

The impact of drinking water quality on mental health and the modifying role of diet

Researchers estimate how exposure to various trace elements in drinking water increases the risk of depression and anxiety.

8 Feb 2024

Monash-led study unveils potential long-term treatment for lupus

Researchers assessed Smith (Sm)-specific regulatory T cells (Tregs) efficacy in halting lupus nephritis (LN) by engineering and testing epitope-targeted Tregs for systemic lupus erythematosus (SLE) treatment.

8 Feb 2024

Study finds gut health key to combating skin diseases, eyes probiotics as potential treatment

Researchers review the significant impact of gut microbiome dysbiosis on skin diseases, suggesting probiotics could offer a new treatment path.

7 Feb 2024

ChatGPT passes the nutrition test, but experts remain irreplaceable

ChatGPT offers accurate nutritional advice aligned with international guidelines for managing non-communicable diseases, yet struggles with complex patient scenarios.

7 Feb 2024

Tiny device could help improve safety, effectiveness of cell therapy for spinal cord injury patients

A tiny device built by scientists at MIT and the Singapore-MIT Alliance for Research and Technology could be used to improve the safety and effectiveness of cell therapy treatments for patients suffering from spinal cord injuries.

7 Feb 2024

Combining clot busters and blood thinners shows no advantage for people with ischemic strokes

Giving blood thinners in addition to clot-busting medications to people with ischemic strokes (clot-caused strokes) did not improve their outcomes 90 days later, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

7 Feb 2024

New treatment target found for CDKL5 deficiency disorder

Scientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy.

7 Feb 2024

Body temperature fluctuations tied to depression severity

Study links higher body temperatures and reduced temperature fluctuations with increased depression severity, suggesting temperature regulation as a potential treatment target.

7 Feb 2024

Study shows link between erectile dysfunction drugs and reduced risk of Alzheimer’s

The drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study published in the February 7, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Feb 2024

Medical Condition News

New drug targets key mechanism in ALS, protects motor neurons

Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

Enzyme released by immune cells may play role in depression

New immunotherapy borrows cancer's tricks to unleash powerful T cells

Flat positioning may give stroke patients an edge before surgery

NCCN publishes first-ever treatment recommendations pertaining to neuroblastoma

Study advances search for a blood test to identify disease-associated changes in the brain

The impact of drinking water quality on mental health and the modifying role of diet

Monash-led study unveils potential long-term treatment for lupus

Study finds gut health key to combating skin diseases, eyes probiotics as potential treatment

ChatGPT passes the nutrition test, but experts remain irreplaceable

Tiny device could help improve safety, effectiveness of cell therapy for spinal cord injury patients

Combining clot busters and blood thinners shows no advantage for people with ischemic strokes

New treatment target found for CDKL5 deficiency disorder

Body temperature fluctuations tied to depression severity

Study shows link between erectile dysfunction drugs and reduced risk of Alzheimer’s

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

Study tracks long COVID's shifting course in general population

Cirrhosis patients face mixed infection outcomes amid pandemic healthcare shifts

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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