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Sangart's MP4CO receives orphan drug designation for acute pain in sickle cell disease

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic (oxygen deprived) tissues through targeted oxygen and other gas delivery, today announced that its investigational biopharmaceutical product, MP4CO, has been awarded orphan drug designation by the U.S. Food and Drug Administration (FDA) for use in treating acute painful sickling crises in patients with sickle cell disease.

15 Nov 2010

New investigational drug is well tolerated in children with nmCF

PTC Therapeutics, Inc. today announced the publication of data from a Phase 2a clinical trial of ataluren in children with nonsense mutation cystic fibrosis (nmCF) in the American Journal of Respiratory and Critical Care Medicine.

15 Nov 2010

Celladon’s Phase 2 CUPID trial shows improved clinical outcomes in advanced heart failure patients

Celladon Corp., a biopharmaceutical company focused on the discovery and development of innovative treatments for cardiovascular diseases, today announced that 12-month data from its Phase 2 CUPID clinical trial of MYDICAR demonstrated significant improvements in clinical outcomes and key disease markers in advanced heart failure patients treated with the genetically-targeted enzyme replacement therapy.

15 Nov 2010

High-dose prescription omega-3 does not reduce recurrence of atrial fibrillation

Although some data have suggested that omega-3 fatty acid supplements, such as from fish oil, may improve treatment of atrial fibrillation, a randomized trial with more than 600 patients finds that treatment with high-dose prescription omega-3 did not reduce the recurrence of atrial fibrillation over six months, according to a study that will appear in the December 1 issue of JAMA. The study is being released early online because it will be presented at the American Heart Association's annual meeting.

15 Nov 2010

Shire announces FDA approval of Vyvanse Capsules CII for ADHD in adolescents

Shire plc, the global specialty biopharmaceutical company, today announced that the US Food and Drug Administration (FDA) approved the prescription medication Vyvanse® (lisdexamfetamine dimesylate) Capsules CII for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in adolescents ages 13 to 17. The approval is based on study data demonstrating that Vyvanse improved ADHD symptoms compared to placebo in adolescents with ADHD. Vyvanse is also indicated for the treatment of ADHD in children ages 6 to 12 years, and adults.

15 Nov 2010

PGxHealth presents results from studies using FAMILION genetic testing at 2010 AHA

Clinical Data, Inc., today announced that results of studies using its FAMILION® genetic testing were presented at the 2010 American Heart Association (AHA) meeting. PGxHealth, a division of Clinical Data, together with its collaborators, presented results from the largest, most comprehensive studies of genetic variation associated with certain cardiac conditions that were revealed using FAMILION testing.

15 Nov 2010

GTx presents preclinical studies of GTx-758 and GTx-230 for treatment of cancer

GTx, Inc. announced the presentation of preclinical studies evaluating GTx-758, a selective estrogen receptor alpha agonist being developed for first line treatment of advanced prostate cancer, and GTx-230, a novel microtubule polymerization inhibitor.

15 Nov 2010

Graphic images of negative consequences of smoking have greatest impact on smokers

Marketing researchers at the University of Arkansas, Villanova University and Marquette University surveyed more than 500 U.S. and Canadian smokers and found that the highly graphic images of the negative consequences of smoking have the greatest impact on smokers' intentions to quit. The most graphic images, such as those showing severe mouth diseases, including disfigured, blackened and cancerous tissue, evoked fear about the consequences of smoking and thus influenced consumer intentions to quit.

15 Nov 2010

50% of nut allergic patients not able to recognize nut types

Only half of people with peanut or tree nut allergies know what the nut they are allergic to looks like, according to a study presented at the American College of Allergy, Asthma and Immunology annual meeting in Phoenix Nov. 11-16. Researchers assembled a nut display that held peanuts and nine tree nuts in 19 different forms. A worksheet, which listed the items, was completed by 1,105 participants 6 years or older. Responses were analyzed based on demographics, presence or absence of food allergies, and occupational history.

15 Nov 2010

No difference in risk of nonsuicide death between ziprasidone and olanzapine for schizophrenia

The potential for harmful side effects associated with anti-psychotic medications for treating schizophrenia is a frustration for mental-health professionals who must balance this with the positive benefits of drugs. For example, the issue of the antipsychotic drug ziprasidone lengthening the QTc interval, a possible indicator of life-threatening heart arrhythmias, has demanded much attention among clinicians since the drug was introduced in 2001.

15 Nov 2010

Study finds asthma care inferior

Researchers assessed asthma burden and treatment practice in the U.S. based on results of the recently completed Asthma Insight and Management telephone survey in a new study presented at the American College of Allergy, Asthma and Immunology annual meeting in Phoenix, Nov. 11-16.

15 Nov 2010

WaterBrook Press releases third edition of Hope, Help and Healing for Eating Disorders

WaterBrook Press recently released the third edition of Hope, Help and Healing for Eating Disorders, A Whole-Person Approach to Treatment of Anorexia, Bulimia and Disorder Eating. The newest edition of this 1995 bestseller on overcoming anorexia, bulimia and other eating disorders from Dr. Gregory L. Jantz, PhD, with Ann McMurray, features the most up-to-date information on body image, food addiction, nutrition and more.

15 Nov 2010

Bronchial thermoplasty helps asthma patients stop taking LABAs

If you have severe persistent asthma, bronchial thermoplasty (BT) may help you stop taking long-acting beta2-agonists (LABAs) according to a new study presented at the American College of Allergy, Asthma and Immunology annual meeting in Phoenix, Nov. 11-16. This novel procedure delivers thermal energy to the airway wall to reduce airway constriction.

15 Nov 2010

New AccuDetect software reduces false-positive rates during mammography screening

Parascript, LLC, the image analysis and pattern recognition technology provider, today announced the release of AccuDetect 4.0, the next generation of its computer-aided detection (CAD) software with significant performance improvements and a greater potential for lowering false-positive rates when detecting suspicious lesions on mammograms, compared to the previous version of the product.

15 Nov 2010

BioWa grants Agensys license to POTELLIGENT Technology

BioWa, Inc. announced today that it has entered into a license agreement with Agensys, Inc., an affiliate of Tokyo based Astellas Pharma Inc., providing Agensys with access to BioWa's POTELLIGENT® Technology platform for the purpose of identifying antibodies with enhanced antibody-dependent cellular cytotoxicity (ADCC).

15 Nov 2010

SuperGen to present three abstracts at EORTC-NCI-AACR International Symposium

SuperGen, Inc., a pharmaceutical company dedicated to the discovery and development of novel cancer therapies, today announced the acceptance of three abstracts detailing recent work with SuperGen compounds.

15 Nov 2010

Study analyzes neurological recovery after hypothermia treatment in cardiac arrest patients

Heart experts at Johns Hopkins say that physicians might be drawing conclusions too soon about irreversible brain damage in patients surviving cardiac arrest whose bodies were for a day initially chilled into a calming coma.

15 Nov 2010

AHA/ASA announce need for comprehensive hospital certification program for heart and stroke care

The American Heart Association should develop a comprehensive hospital certification program with policies and evidence-based criteria for cardiovascular disease and stroke care in the United States, according to an American Heart Association Presidential Advisory published in Circulation: Journal of the American Heart Association.

15 Nov 2010

Diffusion Tensor Imaging MRI technique helps produce satisfactory images of nerve bundles

Standard MRI scans have so far been unable to produce satisfactory images of nerve bundles. However, this is now possible by an MRI technique called Diffusion Tensor Imaging (DTI). Matthan Caan succeeded in improving the DTI method during his PhD research at TU Delft, enabling him to produce more accurate images of the damage that radiotherapy and chemotherapy cause in young leukaemia patients.

15 Nov 2010

Occurrence of atrial fibrillation in first-degree relatives increases AF risk factors

An examination of the heritability of atrial fibrillation (AF) among more than 4,000 participants in the Framingham Heart Study finds the occurrence of AF in first-degree relatives was associated with AF risk after adjustment for established AF risk factors and AF-related genetic variants, according to a study that will appear in the November 24 issue of JAMA.

15 Nov 2010

Medical Condition News

Sangart's MP4CO receives orphan drug designation for acute pain in sickle cell disease

New investigational drug is well tolerated in children with nmCF

Celladon’s Phase 2 CUPID trial shows improved clinical outcomes in advanced heart failure patients

High-dose prescription omega-3 does not reduce recurrence of atrial fibrillation

Shire announces FDA approval of Vyvanse Capsules CII for ADHD in adolescents

PGxHealth presents results from studies using FAMILION genetic testing at 2010 AHA

GTx presents preclinical studies of GTx-758 and GTx-230 for treatment of cancer

Graphic images of negative consequences of smoking have greatest impact on smokers

50% of nut allergic patients not able to recognize nut types

No difference in risk of nonsuicide death between ziprasidone and olanzapine for schizophrenia

Study finds asthma care inferior

WaterBrook Press releases third edition of Hope, Help and Healing for Eating Disorders

Bronchial thermoplasty helps asthma patients stop taking LABAs

New AccuDetect software reduces false-positive rates during mammography screening

BioWa grants Agensys license to POTELLIGENT Technology

SuperGen to present three abstracts at EORTC-NCI-AACR International Symposium

Study analyzes neurological recovery after hypothermia treatment in cardiac arrest patients

AHA/ASA announce need for comprehensive hospital certification program for heart and stroke care

Diffusion Tensor Imaging MRI technique helps produce satisfactory images of nerve bundles

Occurrence of atrial fibrillation in first-degree relatives increases AF risk factors

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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