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Science and precedent do not support biosimilar approach for plasma protein therapies

The current science and experience does not support the safety and efficaciousness of a biosimilar pathway for plasma protein therapies. At a public hearing last week, the Plasma Protein Therapeutics Association (PPTA) urged the United States Food and Drug Administration (FDA) to make patient safety its top priority by adopting a global approach in its evaluation of plasma protein therapies for the biosimilars process.

15 Nov 2010

Talecris announces publication of A1PI studies for AAT deficiency in Respiratory Research journal

Talecris Biotherapeutics announced today the publication of combined data from two studies demonstrating that augmentation therapy with Alpha(1)-Proteinase Inhibitor (Human) (A1PI) significantly reduces lung tissue loss in patients with emphysema related to Alpha(1)-antitrypsin (AAT) deficiency.

15 Nov 2010

Study finds obesity and super obesity associated with increased risk of asthma

Asthma is reaching epidemic levels in the U.S., with 8 percent of the total population and 10 percent of the African-American population suffering from this disease. Obesity rates are also increasing, now affecting 34 percent of the population.

15 Nov 2010

Regular exercise could reduce risk of developing physical, mental health conditions

People who take regular exercise could reduce their risk of developing around two dozen physical and mental health conditions including some cancers and dementia and slow down how quickly their body deteriorates as they age.

15 Nov 2010

TU/e researchers image stages of calcification process in atherosclerosis

Atherosclerosis is characterized by hardening and thickening of artery walls, with serious health consequences. Researchers at Eindhoven University of Technology (TU/e) have imaged the stages in the calcification process at a nanometer scale.

15 Nov 2010

Scios announces results of ASCEND-HF trial for ADHF treatment

Scios Inc. announced today that the landmark investigational study of NATRECOR (nesiritide) for the treatment of acutely decompensated heart failure (ADHF), ASCEND-HF, demonstrated no statistically significant difference from placebo in the co-primary endpoints of dyspnea, measured at six and 24 hours, or in the composite of heart failure re-hospitalizations and death during the first 30 days following treatment.

15 Nov 2010

Bariatric surgery improves disease symptoms in obese heart failure patients

A small Mayo Clinic study has found that morbidly obese heart failure patients who undergo bariatric surgery gain long-lasting and meaningful improvements in disease symptoms and quality of life. The results were presented today at the American Heart Association's Scientific Sessions 2010 in Chicago.

15 Nov 2010

Santarus announces commercial U.S. launch of CYCLOSET for type 2 diabetes mellitus

Santarus, Inc., a specialty biopharmaceutical company, today announced the commercial U.S. launch of CYCLOSET (bromocriptine mesylate) tablets. CYCLOSET is a prescription drug approved by the U.S. Food and Drug Administration (FDA) as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus both as monotherapy and in combination with other oral antidiabetic agents.

15 Nov 2010

Study finds extensive natural recovery after spinal cord injury

A study led by researchers in the Department of Neurosciences at the University of California, San Diego School of Medicine shows unexpected and extensive natural recovery after spinal cord injury in primates. The findings, to be published November 14 in the advance online edition of Nature Neuroscience, may one day lead to the development of new treatments for patients with spinal cord injuries.

15 Nov 2010

Bereaved patients have increased heart rate and reduced heart rate variability: Study

The death of a spouse or child can cause elevated heart rate and other potentially harmful heart rhythm changes among the recently bereaved, according to research presented at the American Heart Association's Scientific Sessions 2010.

15 Nov 2010

Reducing salt consumption in teenage minimizes hypertension in adulthood

Eating smaller amounts of salt each day as a teenager could reduce high blood pressure, heart disease and stroke in adulthood, according to research presented at the American Heart Association's Scientific Sessions 2010.

15 Nov 2010

Tufts University professor receives NIH Director's New Innovator Award

Joshua Kritzer, assistant professor in the School of Arts and Sciences Department of Chemistry at Tufts University, has been awarded one of 33 NIH Director's New Innovator Awards, one of the most prestigious grants awarded by the National Institutes of Health.

15 Nov 2010

ICS/LABA combination therapy increases asthma-related pharmacy cost

Researchers find inhaled corticosteroid and long-acting beta agonist (ICS/LABA) combination products are commonly used by patients with mild asthma, despite the lack of evidence or guidelines for such use.

15 Nov 2010

Study shows patient-specific factors delay skin cancer treatment

If detected early, nonmelanoma skin cancers (primarily basal cell and squamous cell carcinomas, the two most common forms of skin cancer) can be easily treated. But when left untreated, these skin cancers can grow and even spread, causing considerably more harm than if they were treated upon initial detection. Now, a new study finds that denial is the top reason why patients delay seeking treatment for skin cancer and shows that this delay results in larger, more serious, skin cancers.

15 Nov 2010

New protocol reduces radiation exposure in pediatric electrophysiology procedures

A protocol that uses continuous real-time radiation monitoring, low-dose imaging programs and requires physician awareness of radiation dose, significantly reduced radiation exposure during electrophysiology procedures and catheter ablations to diagnose and treat heart arrhythmias in children, according to research presented at the American Heart Association's Scientific Sessions 2010.

15 Nov 2010

Spontaneous mutations can cause mental retardation

Dutch geneticists affiliated with the Radboud University Nijmegen Medical Centre present as a novel research paradigm that spontaneous mutations are an important cause of mental retardation.

15 Nov 2010

Bluhm Cardiovascular Institute implants VAD device to help individuals with advanced heart failure

The Bluhm Cardiovascular Institute of Northwestern Memorial Hospital recently implanted a patient with two of the smallest experimental ventricular assist devices (VADs) currently available for study in humans. VADs are designed to assist either the right (RVAD) or left (LVAD) ventricle, or both (BiVAD) at once.

15 Nov 2010

Dialysis patients at elevated risk for sudden cardiac death: Study

Approximately 500,000 Americans require dialysis to treat kidney disease; of that population nearly half of the deaths that occur are caused by cardiovascular disease. Dialysis patients are at elevated risk for sudden cardiac death, but physicians are unclear why these deaths occur because little research has been done to examine how to best manage heart disease in this high-risk population.

15 Nov 2010

Young father receives life-saving intervention prior heart transplant surgery

James "Jimmy" Armstrong hadn't missed a "Mac" in 28 years. At 44, he's one of the youngest "goats" in the Chicago Yacht Club. Sailors receive the designation of "goat" once they've completed 20 or more "Macs", the 333-mile boat race from Chicago to Mackinac, Mich. Armstrong has sailed the race every year since he was 16. But, he wasn't among the sailors this past July. Instead, he was in intensive care awaiting heart transplant following a harrowing experience spurred by severe case of myocarditis-a little-known condition causing inflammation of the heart muscle.

15 Nov 2010

Combination of Chinese herbal formula and conventional treatments may help treat food allergies

Complementary and alternative medicine may give allergy and asthma sufferers new options for treating symptoms, according to allergists at the annual scientific meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Phoenix, Nov. 11-16. Allergists discussed how herbal treatments may be integrated into conventional allergy treatments, including a novel Chinese herbal formula for treating all types of food allergies.

15 Nov 2010

Medical Condition News

Science and precedent do not support biosimilar approach for plasma protein therapies

Talecris announces publication of A1PI studies for AAT deficiency in Respiratory Research journal

Study finds obesity and super obesity associated with increased risk of asthma

Regular exercise could reduce risk of developing physical, mental health conditions

TU/e researchers image stages of calcification process in atherosclerosis

Scios announces results of ASCEND-HF trial for ADHF treatment

Bariatric surgery improves disease symptoms in obese heart failure patients

Santarus announces commercial U.S. launch of CYCLOSET for type 2 diabetes mellitus

Study finds extensive natural recovery after spinal cord injury

Bereaved patients have increased heart rate and reduced heart rate variability: Study

Reducing salt consumption in teenage minimizes hypertension in adulthood

Tufts University professor receives NIH Director's New Innovator Award

ICS/LABA combination therapy increases asthma-related pharmacy cost

Study shows patient-specific factors delay skin cancer treatment

New protocol reduces radiation exposure in pediatric electrophysiology procedures

Spontaneous mutations can cause mental retardation

Bluhm Cardiovascular Institute implants VAD device to help individuals with advanced heart failure

Dialysis patients at elevated risk for sudden cardiac death: Study

Young father receives life-saving intervention prior heart transplant surgery

Combination of Chinese herbal formula and conventional treatments may help treat food allergies

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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