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Community health workers champion genetic literacy for minorities

Changes to DNA, known as mutations, can increase the likelihood of developing cancer. Specifically, people with mutations in their BRCA 1 and 2 genes are substantially more likely to develop hereditary breast and ovarian cancers. But how do people know if they have these mutations?

12 Jan 2024

3D nanomatrix vascular sheet model for high-throughput atherosclerosis drug testing

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

12 Jan 2024

Drinkable, carbon monoxide-infused foam supercharges cancer therapy

Did smokers do better than non-smokers in a clinical trial for an experimental cancer treatment? That was the intriguing question that led University of Iowa researchers and their colleagues to develop a drinkable, carbon monoxide-infused foam that boosted the effectiveness of the therapy, known as autophagy inhibition, in mice and human cells.

12 Jan 2024

Cedars-Sinai pioneers method to identify dementia patients for better care

Cedars-Sinai investigators are using electronic health records to identify hospitalized patients likely to have dementia.

12 Jan 2024

Defective gene triggers uncontrolled immune attack in young lupus patients

A group of researchers lead by Min Ae Lee-Kirsch from the Department of Pediatrics, Medical Faculty, TUD Dresden University of Technology (Germany), studied four patients from two families who developed symptoms of SLE in the first years of life.

12 Jan 2024

New approach using ultrasound-guided drug delivery effectively targets lymph node metastasis

Researchers at Tohoku University have discovered a new approach for treating lymph node metastasis. Anticancer drugs are administered directly into the LNs under ultrasound guidance (Lymphatic Drug Delivery System or LDDS) to target sentinel lymph nodes (LNs) and generate antitumor effects locally, preventing distant metastasis.

12 Jan 2024

Unequal access to cancer care persists across U.S. states due to insurance variations

A new study led by American Cancer Society (ACS) researchers shows substantial state variations in health insurance coverage, which is a strong determinant of cancer care access and survival, among newly diagnosed cancer patients in the United States.

12 Jan 2024

AI models for mental health hit generalizability snag

Scientists from Yale and the University of Cologne were able to show that statistical models created by artificial intelligence (AI) predict very accurately whether a medication responds in people with schizophrenia.

12 Jan 2024

Gum bacteria fuel COPD through immune cell activation

Severe gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding of how the connection plays out in the immune system remains unclear.

12 Jan 2024

Uncovering the role of ER-mitochondria connections in muscle atrophy

The loss of muscle mass, or muscle atrophy, is a relatively common condition in today's aging and increasingly sedentary societies.

12 Jan 2024

Obesity linked to 73% higher risk of precursor to blood cancer

Individuals with obesity are more likely to have monoclonal gammopathy of undetermined significance (MGUS), a benign blood condition that often precedes multiple myeloma, according to new research published in Blood Advances.

12 Jan 2024

Study reports a prominent increase in substance use and cardiovascular disease‐related mortality in the United States between 1999 and 2019

Researchers evaluated trends in substance use and cardiovascular disease-related mortality in the United States using Centers for Disease Control and Prevention data.

12 Jan 2024