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Finnish study finds revised dementia guidelines did not reduce psychotropic use

A recent register-based study examined the impact of Finland's revised clinical guidelines for the treatment of dementia, published in 2017, on the trend of users of psychotropics in older people with dementia in 2009-2020.

25 Sep 2023

Diabetes incidence significantly increased among youth during COVID-19 pandemic

Diabetes incidence among youth in the United States before and during the coronavirus disease 2019.

25 Sep 2023

Do stroke and hypertension mediate associations between exposure to air pollutants and dementia?

Whether stroke or hypertension modifies or mediates the relationship between particulate matter exposure and dementia.

25 Sep 2023

AI-Doctor's accuracy in retinal disease detection redefines medical diagnosis

An advanced artificial Intelligence (AI) system designed to interpret fundus fluorescein angiography (FFA) images precisely.

25 Sep 2023

Long-term consumption of ultra-processed foods may increase depression risk

The effects of ultra-processed food (UPF) on mental health.

25 Sep 2023

Is BMI the optimal adiposity marker to assess mortality risk?

Researchers evaluated adiposity markers to determine the marker with the most consistent association mortality.

25 Sep 2023

Tirzepatide outshines other treatments in lowering blood sugar and weight for type 2 diabetes patients

Meta-analysis finds tirzepatide to be the most effective GLP-1 receptor agonist for glucose and weight control in type 2 diabetes patients. The study suggests tirzepatide could be preferable in initial stages of the disease, while other GLP-1 receptor agonists combined with insulin are equally effective for long-term diabetics.

25 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

Could metformin be a game changer for heart health in non-diabetics?

Using Mendelian randomization, researchers found that altering seven metformin targets led to improved blood pressure and BMI in non-diabetic individuals. The study suggests the potential for metformin's role in reducing cardiovascular risks in the general population, although more research is needed.

24 Sep 2023

Has the COVID-19 pandemic widened the mental health gap in the UK?

The study explores the varying mental health impacts of the COVID-19 pandemic on the UK's adult population, revealing increased inequalities and distress. Utilizing both surveys and focus group discussions, the research emphasizes the urgent need for targeted interventions and policy responses to address deteriorating mental health and growing disparities.

24 Sep 2023

Genetic link between migraines and breast cancer risk uncovered

Using Mendelian randomization analysis, the study finds a genetic link between migraine susceptibility and increased risk of overall and estrogen receptor-positive breast cancer. However, the findings suggest caution in interpretation, highlighting the need for further research to solidify these associations.

24 Sep 2023

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Researchers compared two commercially available blood tests based on the biomarker p-tau217 for diagnosing Alzheimer's disease in 294 patients. Both tests demonstrated robust diagnostic capabilities, strongly correlating with established Alzheimer's biomarkers from PET scans.

24 Sep 2023

Everyday chemicals linked to increased cancer risk, especially in women

This study identifies links between exposure to chemicals like PFAS, parabens, and phenols and increased cancer risk, particularly among women and across racial groups. The findings spotlight the role of environmental toxins in hormone-related cancers, suggesting new avenues for cancer prevention and mitigation strategies.

24 Sep 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023

Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Scientists studying Alzheimer's disease (AD) have identified thousands of genetic variants in the genome in the development of this progressive neurodegenerative disease.

23 Sep 2023

Photobiomodulation in sleep has more therapeutic effects for Alzheimer's disease than in wakefulness

It is well known that sleep is the best medication. However, it is still unknown why the brain recovers better in sleep and whether these processes can be controlled.

22 Sep 2023

Mechanoresilient cancer cells more prone to metastasis

The ability of cancer cells to metastasize, or spread from one part of the body to another, is one of the reasons why cancer can be extremely challenging to treat.

22 Sep 2023

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

By means of CRISPR screening, LMU researchers have provided the first ever comprehensive molecular characterization of T cell infiltration into the central nervous system of people with MS.

22 Sep 2023

Tirzepatide superior to semaglutide for blood sugar control and body weight loss

A new meta-analysis combining 22 studies, to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 October), shows that tirzepatide is superior to semaglutide for both control of blood sugar and in terms of amount of body weight lost by patients.

22 Sep 2023

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations.

22 Sep 2023

Medical Condition News

Finnish study finds revised dementia guidelines did not reduce psychotropic use

Diabetes incidence significantly increased among youth during COVID-19 pandemic

Do stroke and hypertension mediate associations between exposure to air pollutants and dementia?

AI-Doctor's accuracy in retinal disease detection redefines medical diagnosis

Long-term consumption of ultra-processed foods may increase depression risk

Is BMI the optimal adiposity marker to assess mortality risk?

Tirzepatide outshines other treatments in lowering blood sugar and weight for type 2 diabetes patients

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Could metformin be a game changer for heart health in non-diabetics?

Has the COVID-19 pandemic widened the mental health gap in the UK?

Genetic link between migraines and breast cancer risk uncovered

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Everyday chemicals linked to increased cancer risk, especially in women

Exercise boosts immune defense in Lynch syndrome patients

Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Photobiomodulation in sleep has more therapeutic effects for Alzheimer's disease than in wakefulness

Mechanoresilient cancer cells more prone to metastasis

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

Tirzepatide superior to semaglutide for blood sugar control and body weight loss

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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