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Spice herbs for diabetes treatment: A focus on Trachyspermum ammi and Pimpinella anisum

Announcing a new article publication for BIO Integration journal. Diabetes mellitus (DM) arises from a cascade of factors, primarily stemming from defective insulin secretion by the pancreas and emergence of insulin resistance.

25 Sep 2023

New guideline with preventive care recommendations aims to promote health equity in Canada

A comprehensive new guideline with 16 preventive care recommendations aims to promote health equity for people disadvantaged because of racism, sexism and other forms of discrimination.

25 Sep 2023

Researchers crack the genetic code of rare form of kidney cancer

The genetic code of a rare form of kidney cancer, called reninoma, has been studied for the first time. In the new paper, published today (25th September) in Nature Communications, researchers at the Wellcome Sanger Institute, Great Ormond Street Hospital and The Royal Free Hospital also revealed a new drug target that could serve as an alternative treatment if surgery is not recommended.

25 Sep 2023

New model paves way to understanding and preventing SUDEP in familial epilepsy

Researchers at the University of Michigan have developed a model for studying one type of familial epilepsy, opening the door to understanding—and eventually targeting—the mechanisms that lead to the disorder and its associated fatalities.

25 Sep 2023

Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric diseases.

25 Sep 2023

Finnish study finds revised dementia guidelines did not reduce psychotropic use

A recent register-based study examined the impact of Finland's revised clinical guidelines for the treatment of dementia, published in 2017, on the trend of users of psychotropics in older people with dementia in 2009-2020.

25 Sep 2023

Diabetes incidence significantly increased among youth during COVID-19 pandemic

Diabetes incidence among youth in the United States before and during the coronavirus disease 2019.

25 Sep 2023

Do stroke and hypertension mediate associations between exposure to air pollutants and dementia?

Whether stroke or hypertension modifies or mediates the relationship between particulate matter exposure and dementia.

25 Sep 2023

AI-Doctor's accuracy in retinal disease detection redefines medical diagnosis

An advanced artificial Intelligence (AI) system designed to interpret fundus fluorescein angiography (FFA) images precisely.

25 Sep 2023

Long-term consumption of ultra-processed foods may increase depression risk

The effects of ultra-processed food (UPF) on mental health.

25 Sep 2023

Is BMI the optimal adiposity marker to assess mortality risk?

Researchers evaluated adiposity markers to determine the marker with the most consistent association mortality.

25 Sep 2023

Tirzepatide outshines other treatments in lowering blood sugar and weight for type 2 diabetes patients

Meta-analysis finds tirzepatide to be the most effective GLP-1 receptor agonist for glucose and weight control in type 2 diabetes patients. The study suggests tirzepatide could be preferable in initial stages of the disease, while other GLP-1 receptor agonists combined with insulin are equally effective for long-term diabetics.

25 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

Could metformin be a game changer for heart health in non-diabetics?

Using Mendelian randomization, researchers found that altering seven metformin targets led to improved blood pressure and BMI in non-diabetic individuals. The study suggests the potential for metformin's role in reducing cardiovascular risks in the general population, although more research is needed.

24 Sep 2023

Has the COVID-19 pandemic widened the mental health gap in the UK?

The study explores the varying mental health impacts of the COVID-19 pandemic on the UK's adult population, revealing increased inequalities and distress. Utilizing both surveys and focus group discussions, the research emphasizes the urgent need for targeted interventions and policy responses to address deteriorating mental health and growing disparities.

24 Sep 2023

Genetic link between migraines and breast cancer risk uncovered

Using Mendelian randomization analysis, the study finds a genetic link between migraine susceptibility and increased risk of overall and estrogen receptor-positive breast cancer. However, the findings suggest caution in interpretation, highlighting the need for further research to solidify these associations.

24 Sep 2023

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Researchers compared two commercially available blood tests based on the biomarker p-tau217 for diagnosing Alzheimer's disease in 294 patients. Both tests demonstrated robust diagnostic capabilities, strongly correlating with established Alzheimer's biomarkers from PET scans.

24 Sep 2023

Everyday chemicals linked to increased cancer risk, especially in women

This study identifies links between exposure to chemicals like PFAS, parabens, and phenols and increased cancer risk, particularly among women and across racial groups. The findings spotlight the role of environmental toxins in hormone-related cancers, suggesting new avenues for cancer prevention and mitigation strategies.

24 Sep 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023

Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Scientists studying Alzheimer's disease (AD) have identified thousands of genetic variants in the genome in the development of this progressive neurodegenerative disease.

23 Sep 2023