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Immune cells present in people months before influenza infection, finds study

St. Jude Children's Research Hospital scientists, in collaboration with the Institute of Environmental Science and Research (ESR) Limited, found that immune cells present in people months before influenza (flu) infection could more accurately predict if an individual would develop symptoms than current methods which primarily rely on antibody levels.

18 Aug 2023

New findings could develop effective vaccines or treatments for chikungunya fever

Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell - perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, can manage to escape antibodies circulating in the bloodstream.

18 Aug 2023

Male diabetics more likely to have lower limb amputation

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 October) shows that among people with type 1 and type 2 diabetes, being divorced is associated with a two-thirds higher risk of lower limb amputation (LLA) (amputations below the knee level) compared with being married, and being male is associated with a 57% higher risk of LLA compared with being female. The study is by Dr Stefan Jansson, Örebro University, Örebro, Sweden, and colleagues.

18 Aug 2023

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

In trials, the antipsychotic drug brexpiprazole (Rexulti) failed to provide a clinically meaningful benefit and increased the risk of death. Yet the US Food and Drug Administration (FDA) has fast tracked its approval, making Rexulti the first antipsychotic for treating agitation in elderly patients with dementia.

18 Aug 2023

Medications for chronic diseases can impair thermoregulation, especially in hot weather

Medications to treat various chronic diseases may hinder the body’s ability to lose heat and regulate its core temperature to optimal levels.

17 Aug 2023

Study opens the door to new treatments for bone regeneration and osteoporosis

A new study of the PhyloBone project of the University of Turku, Finland, identifies hundreds of non-collagenous proteins in the bone matrix that may play regulatory roles in bone formation and regeneration.

17 Aug 2023

Study reveals the roles of a nucleic acid sensor for COVID-19 in pan-cancer

Toll-like receptor 7 (TLR7), a severe acute respiratory syndrome 2 (SARS-CoV-2) virus's nucleic acid sensor, was discovered to be aberrantly expressed in many types of cancers.

17 Aug 2023

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Patients with pancreatic cancer who took the benzodiazepine lorazepam (Ativan), commonly prescribed to treat anxiety during cancer treatment, had a shorter progression-free survival than patients who did not, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

17 Aug 2023

AI model can detect atrial septal defect in ECGs with high accuracy

The AI model was more efficient at detecting signatures of atrial septal defect (ASD) in electrocardiograms (ECG) than traditional methods.

17 Aug 2023

Anxious people use different part of brain for social behavior

When choosing their behavior in socially difficult situations, anxious people use a less suitable section of the forebrain than people who are not anxious.

17 Aug 2023

Moffitt receives NCI grant to investigate virus-associated tumors among HIV patients in sub-Saharan Africa

The Center for Immunization and Infection Research in Cancer at Moffitt Cancer Center is expanding its viral infection research in Africa. The cancer center has received a $5.5 million, five-year specialized research center grant (U54CA277834) from the National Cancer Institute to investigate virus-associated tumors that disproportionately impact men and women living with HIV in sub-Saharan Africa.

17 Aug 2023

Obesity impairs brain's ability to learn associations

To control our behavior, the brain must be able to form associations. This involves, for example, associating a neutral external stimulus with a consequence following the stimulus (e.g., the hotplate glows red - you can burn your hand).

17 Aug 2023

Immunotherapy combination extends progression-free survival in patients with melanoma

A research team co-led by UCLA investigators has shown that an immunotherapy drug combination can be an effective second-line therapy for patients with an aggressive and deadly type of melanoma that is resistant to the widely used immunotherapy drugs known as PD-1 inhibitors.

17 Aug 2023

Exposure to interpersonal violence throughout childhood or adulthood increases risk of diabetes

According to the results of a new study in the American Journal of Preventive Medicine, published by Elsevier, exposure to interpersonal violence throughout childhood or adulthood increases an individual's chance of developing adult-onset diabetes by more than 20%.

17 Aug 2023

Metabolic changes after gastric bypass surgery reverse within one year

A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving gastric bypass.

17 Aug 2023

Study finds how low levels of the TET2 gene fuel rapid growth of acute myeloid leukemia

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have identified how low levels of the TET2 gene fuel the rapid growth of acute myeloid leukemia in animal models.

17 Aug 2023

New insights into the role of liver progenitor cells in liver cancer initiation

Primary liver cancers ranked as the sixth most commonly diagnosed cancers and the third leading cause of cancer-related death in 2020. Among all primary liver cancers, HCC is the most common cancer, accounting for more than 80% of cases with a 5-year survival rate of less than 10% in Western countries.

17 Aug 2023

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have been awarded a grant from the U.S. Department of Defense (DoD)'s Congressionally Directed Medical Research Program to target chemotherapy resistance in pancreatic cancer.

17 Aug 2023

Recreational drug use may worsen outcomes for cardiac intensive care patients

Recreational drug use may be a factor in a significant proportion of admissions to cardiac intensive care, with various substances detected in 1 in 10 such patients, suggest the findings of a multicentre French study published online in the journal Heart.

17 Aug 2023

New small molecule drug targets active state of cancer-causing KRAS mutant

A new small molecule drug helps to bind the naturally occurring cellular chaperone cyclophilin A (CYPA) to the active state of the cancer-causing mutant KRASG12C, disrupting oncogenic signaling and tumor growth in several models of human cancer.

17 Aug 2023

Medical Condition News

Immune cells present in people months before influenza infection, finds study

New findings could develop effective vaccines or treatments for chikungunya fever

Male diabetics more likely to have lower limb amputation

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

Medications for chronic diseases can impair thermoregulation, especially in hot weather

Study opens the door to new treatments for bone regeneration and osteoporosis

Study reveals the roles of a nucleic acid sensor for COVID-19 in pan-cancer

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

AI model can detect atrial septal defect in ECGs with high accuracy

Anxious people use different part of brain for social behavior

Moffitt receives NCI grant to investigate virus-associated tumors among HIV patients in sub-Saharan Africa

Obesity impairs brain's ability to learn associations

Immunotherapy combination extends progression-free survival in patients with melanoma

Exposure to interpersonal violence throughout childhood or adulthood increases risk of diabetes

Metabolic changes after gastric bypass surgery reverse within one year

Study finds how low levels of the TET2 gene fuel rapid growth of acute myeloid leukemia

New insights into the role of liver progenitor cells in liver cancer initiation

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

Recreational drug use may worsen outcomes for cardiac intensive care patients

New small molecule drug targets active state of cancer-causing KRAS mutant

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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