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Breakthrough discovery could lead to new treatments for brain metastases

When cancer that starts in the body metastasizes to the brain, it is almost always lethal, in part because so few treatment options exist. Now a new study by Wistar scientists published in Nature Communications shows that a type of brain cell called astrocytes plays an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells.

24 Jun 2023

Type 2 diabetes is frequently overlooked in clinical trials, analysis reveals

New analysis of official records from the National Institute of Health (NIH) have revealed that just 365,000 people took part in a clinical trial for Type 2 Diabetes in 2021, despite 37.3 million people in the US living with the condition - or more than 11% of the population.

24 Jun 2023

Adopting a 30th birthday genetic profile test could save lives and NHS costs

A new study published in the US medical journal ‘The Annals of Internal Medicine’ makes a very strong case for universal genetic testing at the age of 30.

24 Jun 2023

UA researcher develops new method to monitor frailty symptoms

A layperson might think of "frail" as simply a synonym for "weak" or "fragile." But in the medical field, frailty is a specific term, meaning – due to factors including inflammation and hormone shifts – a patient has a lack of physiological reserve, or a reduced ability to tolerate stress.

23 Jun 2023

BMI under fire as AMA calls for new approach to address weight

Body mass index as a standard measure of healthy or unhealthy weight, is once again being called into question with the American Medical Association recommending physicians deemphasize BMI in patient care and employ other ways to address weight.

23 Jun 2023

Stanford and Intonation partner to develop new treatments for neuroendocrine tumors

Stanford University's Innovative Medicines Accelerator (IMA) and Intonation Research Laboratories (Intonation) have formed a collaboration to develop treatments that target cancerous neuroendocrine tumors, or tumors that form from hormone-releasing cells.

23 Jun 2023

New category of depression identified

Scientists at Stanford Medicine conducted a study describing a new category of depression - labeled the cognitive biotype - which accounts for 27% of depressed patients and is not effectively treated by commonly prescribed antidepressants.

23 Jun 2023

IgA nephropathy: The disease that lies outside the kidney

The cause of a common kidney disease likely lies outside the kidney, according to a new study led by Columbia University researchers.

23 Jun 2023

Single-cell profiling reveals immune cell marker and regulator of anti-tumor immunity

B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown.

23 Jun 2023

Eliminating cancer cell repopulation may be the key to curing cancer

A new research perspective was published in Oncoscience (Volume 10) on June 1, 2023, entitled, "Cancer cell repopulation after therapy: which is the mechanism?"

23 Jun 2023

3D models of ovarian cancer reveal how cell’s location can affect tumor biology

Using 3-D models of ovarian cancer tumors, scientists found differences in gene activity based on where a cell is in a tumor, demonstrating how a cell's location and environment in a cancerous tumor can strongly influence which genes are active and the cell's role in the cancer's biology.

23 Jun 2023

Football players at risk for CTE based on cumulative force of head hits, study shows

For years, researchers studying chronic traumatic encephalopathy, or CTE, believed the primary cause of it was repetitive hits to the head, whether or not those hits caused concussions.

23 Jun 2023

Study reveals wide discrepancies among U.S. states in treating opioid use disorder

Despite a national opioid overdose epidemic supercharged by a surge of illicit fentanyl, new research from Oregon Health & Science University reveals wide discrepancies among U.S. states in effectively treating opioid use disorder among people covered by Medicaid.

23 Jun 2023

AHA awards $20 million to address health challenges in rural communities

People who live in rural areas of the U.S. are 40% more likely to develop heart disease and have a 30% higher risk of stroke than people who live in urban areas, according to data reported in the 2020 Call to Action: Rural Health: A Presidential Advisory From the American Heart Association and American Stroke Association.

23 Jun 2023