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How different stages of sleep affect the enhancement or impairment of emotional memories

In a recent study posted to the bioRxiv* preprint server, researchers investigated which stage of sleep is involved in emotional memory consolidation.

6 Mar 2023

A measure of residual inflammatory risk may be a powerful predictor of future cardiovascular events

New evidence released today from a study of 31,245 patients already taking statin therapy indicates that inflammation may be a more powerful predictor of risk of future cardiovascular events - such as heart attack and stroke - than "bad" cholesterol.

6 Mar 2023

Evaluating how bacterial therapeutics may synergize with existing anti-cancer therapies

It may come as a surprise, but bacteria love to grow inside tumors. It's the environment - tumors are typically acidic, have low amounts of oxygen, and are filled with dead cells, which all facilitate bacterial growth.

6 Mar 2023

How SARS-CoV-2 infection affects acute ischemic stroke outcomes

A recent PLOS ONE journal study evaluated the impact of COVID-19 on neurological outcomes in acute ischemic stroke patients.

6 Mar 2023

Most athletes with diagnosed and treated genetic heart disease experienced no cardiac events

Ninety-five percent of athletes with a diagnosed and treated genetic heart disease experienced no disease-triggered cardiac events, such as cardiogenic fainting or seizures, implantable cardio-defibrillator (ICD) shocks, sudden cardiac arrest or sudden cardiac death, during an average of seven years of follow up, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

How maternal obesity and gestational diabetes can impact DNA methylation in infants

A study published in the journal Cardiovascular Diabetology describes that maternal obesity and gestational diabetes can induce epigenetic remodeling in infants, potentially impacting metabolic and developmental pathways.

6 Mar 2023

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

MK-0616, an experimental oral proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, met its primary endpoint and substantially reduced levels of low-density lipoprotein (LDL) cholesterol in people with high cholesterol and/or heart disease related to clogged arteries, in a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Addition of sotatercept to existing therapy shows promise for the treatment of pulmonary arterial hypertension

Patients with pulmonary arterial hypertension (PAH), a severe, progressive condition that affects the heart and lungs, who were treated with the novel first-in-class medication sotatercept on top of existing therapy experienced significant improvements in walking distance via a six-minute walking test—the study's primary endpoint and a validated surrogate for functional improvement and reduced symptom burden.

6 Mar 2023

Young people also at risk of colorectal cancer

When Nikki Lawson started to experience some pretty disruptive gastrointestinal discomfort at 35, she chalked it up to her food choices.

6 Mar 2023

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

The influenza season marks the beginning of a time of illness, sometimes serious or even fatal, in much of the world. For this reason, flu shots are recommended, especially for individuals with underlying diseases such as chronic hepatitis B (CHB) infection, since they are at higher risk for adverse outcomes.

6 Mar 2023

Vigorous exercise does not increase risk of serious cardiac events in people with hypertrophic cardiomyopathy

People with the inherited heart condition hypertrophic cardiomyopathy (HCM) who exercised vigorously did not have an increased incidence of serious cardiac events during three years of follow-up compared with people who exercised moderately or were inactive, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Fighting pancreatic cancer with gene and cell biotherapies

Pancreatic cancer is an incurable form of cancer, and gene therapies are currently in clinical testing to treat this deadly disease. A comprehensive review of the gene and cell biotherapies in development to combat pancreatic cancer is published in the peer-reviewed journal Human Gene Therapy.

6 Mar 2023

Wrist-worn device can accurately predict troponin-I and obstructed arteries in five minutes

An experimental wrist-worn device was found to predict troponin-I and obstructed arteries with 90% accuracy in five minutes, according to research being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Stick-on sensor alerts clinicians about heart failure complications

People with heart failure were 38% less likely to be readmitted to the hospital for heart failure complications within 90 days if they wore a stick-on sensor that alerted their clinician about fluid buildup in the lungs, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

New ablation technology successful at eliminating episodes of abnormal heart rhythms

A new ablation technology known as pulsed-field ablation was successful at eliminating episodes of abnormal heart rhythms for 12 months in up to two-thirds of patients, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Fixed-dose combination therapy provides better results than monotherapy for pulmonary hypertension

Patients with pulmonary arterial hypertension (high blood pressure in the arteries that supply the lungs, also called PAH) had approximately double the reduction in pulmonary vascular resistance (PVR) if they took the PAH medications macitentan (10 mg) and tadalafil (40 mg) together in a single tablet rather than either drug alone, according to research being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Coordinated, multifaceted intervention can improve preventive care for diabetes, heart disease

A multifaceted intervention to improve prescribing practices increased the likelihood that patients with Type 2 diabetes and heart disease would be prescribed three classes of guideline-recommended medications by more than fourfold, according to research being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

People with atopy have lower prevalence of cancers in extracutaneous sites and reduced melanoma risk

Fewer cases of melanoma were observed in people with a history of atopic diseases, such as allergic asthma or rhinitis, than in nonatopic people.

6 Mar 2023

Researchers optically evoke tachycardia enhanced anxiety-like behaviour

In a recent study published in the journal Nature, researchers devised a non-invasive optogenetic and wearable cardiac pacemaker for accurate and specific control of cardiac rhythm for ≤900 beats per minute (bpm), enabled by micro-light-emitting display (LED) harness and systemic channelrhodopsin delivery.

6 Mar 2023

Even small bouts of exercise protective against heart disease, cancer

In a recent article published in the British Journal of Sports Medicine, researchers explored the relationship between non-occupational physical activity (PA) levels and poor cardiovascular diseases (CVDs) and cancer outcomes, including mortality.

5 Mar 2023

Medical Condition News

How different stages of sleep affect the enhancement or impairment of emotional memories

A measure of residual inflammatory risk may be a powerful predictor of future cardiovascular events

Evaluating how bacterial therapeutics may synergize with existing anti-cancer therapies

How SARS-CoV-2 infection affects acute ischemic stroke outcomes

Most athletes with diagnosed and treated genetic heart disease experienced no cardiac events

How maternal obesity and gestational diabetes can impact DNA methylation in infants

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

Addition of sotatercept to existing therapy shows promise for the treatment of pulmonary arterial hypertension

Young people also at risk of colorectal cancer

How does chronic HBV infection affect flu and COVID-19 vaccine responses?

Vigorous exercise does not increase risk of serious cardiac events in people with hypertrophic cardiomyopathy

Fighting pancreatic cancer with gene and cell biotherapies

Wrist-worn device can accurately predict troponin-I and obstructed arteries in five minutes

Stick-on sensor alerts clinicians about heart failure complications

New ablation technology successful at eliminating episodes of abnormal heart rhythms

Fixed-dose combination therapy provides better results than monotherapy for pulmonary hypertension

Coordinated, multifaceted intervention can improve preventive care for diabetes, heart disease

People with atopy have lower prevalence of cancers in extracutaneous sites and reduced melanoma risk

Researchers optically evoke tachycardia enhanced anxiety-like behaviour

Even small bouts of exercise protective against heart disease, cancer

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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