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Social isolation is a risk factor for dementia in community-dwelling older adults, studies show

In two studies using nationally representative data from the National Health and Aging Trends Study gathered on thousands of Americans, researchers from the Johns Hopkins University School of Medicine and Bloomberg School of Public Health have significantly added to evidence that social isolation is a substantial risk factor for dementia in community-dwelling (noninstitutionalized) older adults, and identified technology as an effective way to intervene.

12 Jan 2023

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

The Alzheimer's Drug Discovery Foundation and Harrington Discovery Institute at University Hospitals in Cleveland have granted an ADDF-Harrington Scholar Award to Christiane Wrann, PhD, DVM, Associate Professor in Medicine at the Cardiovascular Research Center and the McCance Center for Brain Health at Massachusetts General Hospital and the Harvard Medical School in Boston.

12 Jan 2023

Experts propose solutions to address racial disparities affecting people with allergic conditions

In February 2022, the American College of Allergy, Asthma and Immunology convened experts in atopic dermatitis (AD) and food allergy to examine the issue of racial disparities affecting people with these conditions.

12 Jan 2023

The same genetic factors may contribute to both cardiometabolic diseases and dementia

Being affected by several cardiometabolic diseases such as diabetes, heart disease and stroke, is linked to a greatly increased risk of dementia and Alzheimer's disease.

12 Jan 2023

Study sheds light on fall-risk factors facing older adults in community-living environments

With falls causing millions of injuries in older adults each year, it is an increasingly important public health concern.

12 Jan 2023

Hernia: A common medical condition that can develop for many reasons

While an impending storm will trigger cautionary news reports about the risk of a heart attack while shoveling snow, you're less likely to hear how twisting and turning while moving heavy amounts of the tiny ice crystals may increase your risk of developing a hernia.

12 Jan 2023

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

New research in the January 2023 issue of JNCCN - Journal of the National Comprehensive Cancer Network finds that immunotherapy from immune checkpoint (PD-1) inhibitors prior to surgery was strikingly effective for patients with localized mismatch repair-deficient or microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC).

12 Jan 2023

IBS-related changes revealed using real time recording with a wearable device

Irritable bowel syndrome (IBS) is a difficult disease to treat, characterized by chronic abdominal pain related to bowel movements, of which there are four types: diarrheal, constipation, mixed, and unclassifiable.

12 Jan 2023

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

With the growing number of skin biopsies performed annually for suspected melanoma, a simple, easily understood standardized classification system for melanocytic lesions is increasingly important to aid pathologists and clinicians who examine millions of tissue samples each year and to alleviate patient confusion and anxiety.

11 Jan 2023

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Oregon State University College of Pharmacy scientists have demonstrated in animal models the possibility of using lipid nanoparticles and messenger RNA, the technology underpinning COVID-19 vaccines, to treat blindness associated with a rare genetic condition.

11 Jan 2023

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases.

11 Jan 2023

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

11 Jan 2023

Medicare policy change may lead to increased inequities in access to heart transplants

A change to Medicare policy surrounding heart transplant may lead to increased inequities in access to transplant for patients with heart failure, a Michigan Medicine study finds.

11 Jan 2023

COVID-19 outcomes in Rituximab treated patients

A new report throws light on SARS-CoV-2 breakthrough infections in patients with certain joint diseases or musculoskeletal conditions who are on rituximab and compares the severity of COVID-19 outcomes in these patients whilst identifying potential risk factors for severe outcomes.

11 Jan 2023

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Severe inflammation weakens the body's ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study shows.

11 Jan 2023

Most clergy embrace a medical understanding of depression’s etiology and treatment

A new Duke University study appears to ease concerns that clergy would steer congregants suffering from depression away from mental health providers and instead rely only on their faith.

11 Jan 2023

Ringlike peripheral high iodine concentration for differentiating pulmonary metastasis from lung cancer

According to an accepted manuscript published in ARRS' American Journal of Roentgenology (AJR), ringlike peripheral high iodine concentration maps from dual-energy CT (DECT) can help guide management in patients with known lung cancer and an indeterminate solitary nodule.

11 Jan 2023

Study may help explain how excess weight can contribute to diabetes

People who are overweight or obese have a significantly increased risk of developing diabetes, but exactly how that happens is not well understood.

11 Jan 2023

Three genes found to be directly associated with cleft lip and palate

Researchers are finding more genes directly associated with cleft lip and palate.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

Medical Condition News

Social isolation is a risk factor for dementia in community-dwelling older adults, studies show

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

Experts propose solutions to address racial disparities affecting people with allergic conditions

The same genetic factors may contribute to both cardiometabolic diseases and dementia

Study sheds light on fall-risk factors facing older adults in community-living environments

Hernia: A common medical condition that can develop for many reasons

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

IBS-related changes revealed using real time recording with a wearable device

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

Using lipid nanoparticles and messenger RNA to treat blindness associated with rare genetic condition

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

Medicare policy change may lead to increased inequities in access to heart transplants

COVID-19 outcomes in Rituximab treated patients

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Most clergy embrace a medical understanding of depression’s etiology and treatment

Ringlike peripheral high iodine concentration for differentiating pulmonary metastasis from lung cancer

Study may help explain how excess weight can contribute to diabetes

Three genes found to be directly associated with cleft lip and palate

Simple method increases the efficacy of T cell therapy by cytokine conjugation

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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