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CU researchers discover a new mechanism for slowing cardiac fibrosis

Researchers at the University of Colorado School of Medicine have discovered a new mechanism for slowing scarring of heart tissue - a process known as cardiac fibrosis.

6 Jan 2023

People with latent tuberculosis infection could be at a higher risk for cardiovascular disease

Newly published research from the University of Cincinnati finds that people with latent tuberculosis infection (LTBI) have more inflammation and could be at a higher risk for cardiovascular disease.

6 Jan 2023

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

The most common type of liver cancer, hepatocellular carcinoma (HCC), is already the third leading cause of cancer-related deaths globally - and cases are on the rise, both in the U.S. and worldwide.

6 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

Talking, smiling, eating together – these are all social activities that are inherent to the human experience. But for some head and neck cancer survivors, they are dreaded tasks.

6 Jan 2023

A need for more research on how lifestyle interventions could help high-risk pregnant populations

The prevalence of chronic hypertension (CH) and type 1 diabetes mellitus (DM) or type 2 diabetes mellitus (T2DM) has increased considerably in the pregnant population over the recent decades. Notably, the percentage of its occurrence has continued to rise due to increasing rates of obesity and advances in maternal age. Obesity is a key risk factor influencing CH or DM/T2DM.

5 Jan 2023

History of obesity produces changes in innate immunity and neuroinflammation

A history of obesity caused by a high-fat diet produces changes in innate immunity that can promote inflammatory disease – changes that persist even after weight loss and a return to normal metabolism, according to a new study in mice.

5 Jan 2023

Intense exercise encourages coronary artery calcification

A recent Circulation journal paper has focused on investigating the relationship between exercise volume and intensity and the progression of coronary atherosclerosis in middle-aged and older male athletes.

5 Jan 2023

Study details the “immunometabolic editing” mechanism of tumor evolution

A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses.

5 Jan 2023

Researchers take an important step forward in treating combat-related post-traumatic stress disorder

Study findings out today in JAMA Network Open show an important step forward in treating the psychological injuries of war.

5 Jan 2023

Historic agreement to accelerate trials into vaccines for cancer and wider diseases

Trials into vaccines for cancer and wider diseases will accelerate after the government reached a historic agreement with a leading biopharmaceutical firm to bring revolutionary research to England.

5 Jan 2023

A gloomy outlook for type 1 diabetes in children and adolescents by 2050

A study published in The Lancet Diabetes and Endocrinology journal estimates the global incidence of type 1 diabetes in children and adolescents using microsimulation models.

5 Jan 2023

Sugar appears to play a role in polycystic kidney disease, study finds

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

5 Jan 2023

Postoperative restrictive opioid protocols reduce long-term opioid use

Research at Roswell Park Comprehensive Cancer Center shows that putting a three-day limit on opioid prescriptions to treat surgical pain after hospital discharge reduces the number of patients who become chronic opioid users without compromising pain relief or recovery.

5 Jan 2023

Irish study demonstrates a genetic effect on the response to obesity treatments

Collaborative research between University of Galway and Brunel University London has found that patients with severe and complicated obesity respond differently to a dietary weight loss program based on their genes.

5 Jan 2023

Intestinal bacteria in multiple sclerosis patients vary with disease activity, study finds

Multiple sclerosis patients do not have the same bacteria in their intestines as healthy people. There are also differences in the composition and function of the bacteria in the intestines of multiple sclerosis patients, depending on whether their illness is active, and whether they are in treatment.

5 Jan 2023

Researchers develop a new approach to better understand the biology of polycystic kidney disease

A research team supported by the National Institutes of Health has developed a new approach to better understand the biology of polycystic kidney disease (PKD), an often-life-threatening genetic disorder that affects millions worldwide.

5 Jan 2023

New machine learning tool can shed light on chronic COVID symptoms

Long COVID has emerged as a pandemic within the pandemic. As scientists work to untangle the many remaining unanswered questions about how the initial infection impacts the body, they must now also investigate why some people develop debilitating, chronic symptoms that last months to years longer.

5 Jan 2023

Wayne State researcher wins $1.7 million NIH award to understand and tackle cisplatin-induced ototoxicity

A Wayne State University researcher has received a $1.7 million, five-year award from the National Institute on Deafness and Other Communication Disorders of the National Institutes of Health for the study, "Targeting nitrative stress for treatment of cisplatin ototoxicity."

5 Jan 2023

SynGAP Research Fund awards $180,000 grant to the University of Edinburgh Medical School's Patrick Wild Centre & Centre for Discovery Brain Sciences

SynGAP Research Fund (SRF), a 501(c)(3) public charity whose mission is to improve the quality of life for SYNGAP1 patients through the research and development of treatments, therapies and support systems, along with SynGAP Research Fund UK, today announced they have awarded a $180,000 grant to the University of Edinburgh Medical School's Patrick Wild Centre & Centre for Discovery Brain Sciences to advance the science around gene transfer to correct SYNGAP1 haploinsufficiency.

5 Jan 2023

Medical Condition News

CU researchers discover a new mechanism for slowing cardiac fibrosis

People with latent tuberculosis infection could be at a higher risk for cardiovascular disease

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

A need for more research on how lifestyle interventions could help high-risk pregnant populations

History of obesity produces changes in innate immunity and neuroinflammation

Intense exercise encourages coronary artery calcification

Study details the “immunometabolic editing” mechanism of tumor evolution

Researchers take an important step forward in treating combat-related post-traumatic stress disorder

Historic agreement to accelerate trials into vaccines for cancer and wider diseases

A gloomy outlook for type 1 diabetes in children and adolescents by 2050

Sugar appears to play a role in polycystic kidney disease, study finds

Postoperative restrictive opioid protocols reduce long-term opioid use

Irish study demonstrates a genetic effect on the response to obesity treatments

Intestinal bacteria in multiple sclerosis patients vary with disease activity, study finds

Researchers develop a new approach to better understand the biology of polycystic kidney disease

New machine learning tool can shed light on chronic COVID symptoms

Wayne State researcher wins $1.7 million NIH award to understand and tackle cisplatin-induced ototoxicity

SynGAP Research Fund awards $180,000 grant to the University of Edinburgh Medical School's Patrick Wild Centre & Centre for Discovery Brain Sciences

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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