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Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

Researchers successfully demonstrated that lab-grown retinal organoids made new synaptic connections, theoretically establishing their potential to treat blindness due to retinal degenerative diseases.

13 Jan 2023

Diabetes diagnosis is more positive in Norway, study says

Diabetes can have major consequences for the health and quality of life of affected people, especially when left undiagnosed. Fortunately, doctors are able to diagnose the vast majority of patients, who can then receive treatment.

13 Jan 2023

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

Scientists from The Australian National University and the Peter MacCallum Cancer Centre have discovered that a protein, called Menin, contributes to abnormal deactivation of specific genes in cancer cells.

13 Jan 2023

Ending involuntary commitments would shift burden of dementia care to strapped communities

State lawmakers from both parties have shown support for a plan to stop the practice of committing people with Alzheimer's disease, other types of dementia, or traumatic brain injuries without their consent to the troubled Montana State Hospital and instead direct them to treatment in their communities.

13 Jan 2023

New cooling strategy could prevent the growth of glioblastoma

Cooling brain tumor cells to stop them from dividing without killing healthy cells extended the survival of glioblastoma (GBM) animal models dramatically in a study led by a UT Southwestern resident.

12 Jan 2023

California Attorney General sues drugmakers over inflated insulin prices

California Attorney General Rob Bonta on Thursday sued the six major companies that dominate the U.S. insulin market, ratcheting up the state's assault on a profitable industry for artificially jacking up prices and making the indispensable drug less accessible for diabetes patients.

12 Jan 2023

American Cancer Society's annual report on cancer facts and trends released

Today, the American Cancer Society released Cancer Statistics, 2023, the organization's annual report on cancer facts and trends. According to the report, overall cancer mortality has dropped 33% since 1991, averting an estimated 3.8 million cancer deaths.

12 Jan 2023

Bacteria play specific roles in cancer

In a recent article published in the journal Immunity, the authors discussed the findings from a 2022 study by Galeano Niño et al., which reported that microbiota associated with tumors form micro-niches and play a role in epithelial and immune mediations of cancer.

12 Jan 2023

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Immune checkpoint inhibitors are important medications that boost the immune system's response against various cancers, but some patients' cancer cells are unaffected by the drugs or develop resistance during treatment.

12 Jan 2023

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

A growing pile of evidence indicates that the tens of trillions of microbes that normally live in our intestines - the so-called gut microbiome - have far-reaching effects on how our bodies function.

12 Jan 2023

Excessive mechanosensation in sensory neurons can cause joint deformities

Excessive mechanosensation in the neurons that enable the sense of one's limbs in space can disrupt musculoskeletal development and cause joint deformities like arthrogryposis, researchers report.

12 Jan 2023

Machine learning-based behavioral intervention can improve end-of-life cancer care

Electronic nudges delivered to health care clinicians based on a machine learning algorithm that predicts mortality risk quadrupled rates of conversations with patients about their end-of-life care preferences, according to the long-term results of a randomized clinical trial published by Penn Medicine investigators in JAMA Oncology today.

12 Jan 2023

Social isolation is a risk factor for dementia in community-dwelling older adults, studies show

In two studies using nationally representative data from the National Health and Aging Trends Study gathered on thousands of Americans, researchers from the Johns Hopkins University School of Medicine and Bloomberg School of Public Health have significantly added to evidence that social isolation is a substantial risk factor for dementia in community-dwelling (noninstitutionalized) older adults, and identified technology as an effective way to intervene.

12 Jan 2023

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

The Alzheimer's Drug Discovery Foundation and Harrington Discovery Institute at University Hospitals in Cleveland have granted an ADDF-Harrington Scholar Award to Christiane Wrann, PhD, DVM, Associate Professor in Medicine at the Cardiovascular Research Center and the McCance Center for Brain Health at Massachusetts General Hospital and the Harvard Medical School in Boston.

12 Jan 2023

Experts propose solutions to address racial disparities affecting people with allergic conditions

In February 2022, the American College of Allergy, Asthma and Immunology convened experts in atopic dermatitis (AD) and food allergy to examine the issue of racial disparities affecting people with these conditions.

12 Jan 2023

The same genetic factors may contribute to both cardiometabolic diseases and dementia

Being affected by several cardiometabolic diseases such as diabetes, heart disease and stroke, is linked to a greatly increased risk of dementia and Alzheimer's disease.

12 Jan 2023

Study sheds light on fall-risk factors facing older adults in community-living environments

With falls causing millions of injuries in older adults each year, it is an increasingly important public health concern.

12 Jan 2023

Hernia: A common medical condition that can develop for many reasons

While an impending storm will trigger cautionary news reports about the risk of a heart attack while shoveling snow, you're less likely to hear how twisting and turning while moving heavy amounts of the tiny ice crystals may increase your risk of developing a hernia.

12 Jan 2023

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

New research in the January 2023 issue of JNCCN - Journal of the National Comprehensive Cancer Network finds that immunotherapy from immune checkpoint (PD-1) inhibitors prior to surgery was strikingly effective for patients with localized mismatch repair-deficient or microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC).

12 Jan 2023

IBS-related changes revealed using real time recording with a wearable device

Irritable bowel syndrome (IBS) is a difficult disease to treat, characterized by chronic abdominal pain related to bowel movements, of which there are four types: diarrheal, constipation, mixed, and unclassifiable.

12 Jan 2023

Medical Condition News

Do hPSC-derived retinal neurons possess intrinsic potential to form new synaptic connections after extraction from organoids?

Diabetes diagnosis is more positive in Norway, study says

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

Ending involuntary commitments would shift burden of dementia care to strapped communities

New cooling strategy could prevent the growth of glioblastoma

California Attorney General sues drugmakers over inflated insulin prices

American Cancer Society's annual report on cancer facts and trends released

Bacteria play specific roles in cancer

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

Excessive mechanosensation in sensory neurons can cause joint deformities

Machine learning-based behavioral intervention can improve end-of-life cancer care

Social isolation is a risk factor for dementia in community-dwelling older adults, studies show

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

Experts propose solutions to address racial disparities affecting people with allergic conditions

The same genetic factors may contribute to both cardiometabolic diseases and dementia

Study sheds light on fall-risk factors facing older adults in community-living environments

Hernia: A common medical condition that can develop for many reasons

Immunotherapy prior to surgery strikingly effective for patients with colorectal cancer

IBS-related changes revealed using real time recording with a wearable device

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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