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New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Scientists are harnessing a new way to turn cancer cells into potent, anti-cancer agents. In the latest work from the lab of Khalid Shah, MS, PhD, at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune system so that it can prevent cancer from recurring.

4 Jan 2023

Researchers discover novel candidate drug targets for advanced non-alcoholic fatty liver disease

Using the latest technologies - including both single-nuclear sequencing of mice and human liver tissue and advanced 3D glass imaging of mice to characterize key scar-producing liver cells - researchers have uncovered novel candidate drug targets for non-alcoholic fatty liver disease (NAFLD).

4 Jan 2023

Distinct genomic patterns of malignant peripheral nerve sheath tumors may help with early diagnosis

Neurofibromatosis type 1 (NF1) is a common genetic condition, affecting 1 in 3000 individuals, and people with NF1 are at greater risk of developing a rare, aggressive form of cancer.

4 Jan 2023

Research offers a cost-effectiveness analysis of anticoagulant drugs for cancer-associated thrombosis

Newly published research out of the University of Cincinnati and the University of California-Davis shows that direct oral anticoagulant (DOAC) drugs are more effective and are more cost-effective than low molecular weight heparin for treating cancer-associated thrombosis.

4 Jan 2023

Dietary supplement can reverse the signs of heart disease in a subset of patients

When we were little, our parents told us to take our vitamins so we could grow big and strong. Now, researchers from Japan find that one particular supplement may even fix a broken heart.

4 Jan 2023

The interrelationship between diet, physical health, and depression

A recent Journal of Affective Disorders study examined the interrelationship between diet, physical health, and depression.

4 Jan 2023

The metabolic links between diet-induced changes in the gut and NASH

Scientists reviewed the metabolic association between diet-induced alterations in the gut and NASH

4 Jan 2023

High burden of multi-food allergies among children and adults in the U.S.

A new study in the journal Annals of Allergy, Asthma & Immunology aimed to characterize the characteristics, prevalence, determinants, distribution, and psychosocial burden of multi-FA among adults and children in the US.

3 Jan 2023

Precise 3D imaging can help measure radiation during cancer treatment

Radiation, used to treat half of all cancer patients, can be measured during treatment for the first time with precise 3D imaging developed at the University of Michigan.

3 Jan 2023

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with poor prognosis and limited treatment options.

3 Jan 2023

Traditional Chinese medicine may help treat neurodegenerative diseases caused by HSV-1 reactivation

Announcing a new publication for Acta Materia Medica journal. Owing to environmental and lifestyle changes in modern society, physical and mental stress is on the rise among the population in attempting to compensate for the changes.

3 Jan 2023

The role of exosomes in osteosarcoma diagnosis, prognosis, and therapeutics

Announcing a new publication for Acta Materia Medica journal. Osteosarcoma, a primary malignant tumor of the skeleton, has a morbidity of 2.5 per 1 million people.

3 Jan 2023

New study to examine the effectiveness of stroke treatment for patients with disabilities

When conducting clinical research, investigators aim to control as many variables as possible so it is easier to examine the effectiveness of new treatments.

3 Jan 2023

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers."

3 Jan 2023

Analyzing electronic medical records to identify COVID-19 sequelae

In a recent study published in the journal Emerging Infectious Diseases, researchers analyzed and compared pre‒ and post‒COVID-19 diagnostic codes to identify symptoms that had higher encounter incidence in the post‒COVID-19 period as sequelae. COVID-19 sequelae and future emerging diseases can be generated and monitored using this method.

3 Jan 2023

Keeping hydrated can reduce aging and extend disease-free life

In a recent study published in the journal eBioMedicine, researchers assessed the association between hydration and aging.

3 Jan 2023

Olive oil is beneficial for maternal-fetal health

There have been numerous studies showing how olive oil affects pregnancy. In a recent study published in the journal Nutrition Research, evidence was gathered for its effects on fetomaternal outcomes. The results are interesting, suggesting a protective effect on these outcomes.

3 Jan 2023

Major update of the INCOG guidelines for cognitive rehabilitation following traumatic brain injury

A rapidly growing body of evidence shows the importance and effectiveness of cognitive rehabilitation for individuals with traumatic brain injury (TBI).

3 Jan 2023

Benefits, challenges in the use of transcatheter pulmonary valve replacement for congenital heart disorders

Patients with congenital heart diseases often suffer from obstructions in the right ventricular outflow tract (RVOT), which carries blood from the heart to the lungs. These obstructions can be repaired with surgical procedures.

3 Jan 2023

Researchers identify novel gene mechanism in most aggressive kidney cancers

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway with loss of the tuberous sclerosis complex (TSC) tumor suppressor gene.

3 Jan 2023

Medical Condition News

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Researchers discover novel candidate drug targets for advanced non-alcoholic fatty liver disease

Distinct genomic patterns of malignant peripheral nerve sheath tumors may help with early diagnosis

Research offers a cost-effectiveness analysis of anticoagulant drugs for cancer-associated thrombosis

Dietary supplement can reverse the signs of heart disease in a subset of patients

The interrelationship between diet, physical health, and depression

The metabolic links between diet-induced changes in the gut and NASH

High burden of multi-food allergies among children and adults in the U.S.

Precise 3D imaging can help measure radiation during cancer treatment

Novel triple immunotherapy combination improves anti-tumor responses in preclinical models of pancreatic cancer

Traditional Chinese medicine may help treat neurodegenerative diseases caused by HSV-1 reactivation

The role of exosomes in osteosarcoma diagnosis, prognosis, and therapeutics

New study to examine the effectiveness of stroke treatment for patients with disabilities

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

Analyzing electronic medical records to identify COVID-19 sequelae

Keeping hydrated can reduce aging and extend disease-free life

Olive oil is beneficial for maternal-fetal health

Major update of the INCOG guidelines for cognitive rehabilitation following traumatic brain injury

Benefits, challenges in the use of transcatheter pulmonary valve replacement for congenital heart disorders

Researchers identify novel gene mechanism in most aggressive kidney cancers

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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