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Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects.

16 Dec 2022

Research project helps to improve the care of adult refugees suffering from PTSD

People who have fled to Germany to escape war and violence often suffered traumatic experiences. Torture, rape or attacks can lead to post-traumatic stress disorder (PTSD): Those affected suffer from symptoms such as nightmares, vivid memories of the trauma, sleep disorders, concentration problems, anxiety and other distressing negative feelings.

16 Dec 2022

NEJM study shows hidden genetic anomaly behind common late-onset cerebellar ataxia

Researchers at the University of Miami Miller School of Medicine, McGill University and other institutions have found that a well-concealed genetic variation in the gene FGF14, called a DNA tandem repeat expansion, causes a common form of late-onset cerebellar ataxia, a brain disorder that interferes with coordinated movement.

16 Dec 2022

Landmark population health study could pave the way for better tools to fight chronic diseases in Asian populations

The Lee Kong Chian School of Medicine at Nanyang Technological University, Singapore, in collaboration with other healthcare institutions here, has embarked on a landmark comprehensive population health study of 100,000 Singaporeans over a few decades to identify the social, environmental, lifestyle, and genetic factors associated with diseases prevalent in Singapore, such as diabetes, hypertension, and cancer.

16 Dec 2022

New support for a serotonin deficit in depression

Since the 1960s, researchers have postulated that major depression stems from disruptions in the serotonin neurotransmitter system, but the evidence for that idea, though plentiful, was indirect.

16 Dec 2022

High performing primary care practices for patients with diabetes during the pandemic

Published in PLOS ONE, University of Minnesota Medical School researchers explored how high performing primary care practices organized care for patients with diabetes during the first months of the COVID-19 pandemic.

16 Dec 2022

Study provides new insights into the pathology of LATE

Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), but LATE is a different condition, with its own risks and causes.

16 Dec 2022

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

The Lupus Research Alliance (LRA) proudly announces the two outstanding recipients of the 2022 Distinguished Innovator Award (DIA): Hongbo Chi, PhD, and Joseph Craft, MD.

16 Dec 2022

Outpatient clinic visits with a nephrologist associated with lower risk of mortality in patients with acute kidney injury

Outpatient clinic visits with a nephrologist and attention to kidney complications and cardiovascular disease were associated with 29% lower risk of mortality compared to standard of care in patients with AKI during recent hospitalization.

16 Dec 2022

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Cleft lip and palate are among the most common congenital malformations, which are mainly due to genetic causes.

16 Dec 2022

Study: People with cluster headaches may be more likely to have other medical conditions

People with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental disorders and other neurologic diseases, according to a study published in the December 14, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

16 Dec 2022

AI-based neural network can detect early knee osteoarthritis from x-ray images

Researchers from the University of Jyväskylä and the Central Finland Health Care District have developed an AI based neural network to detect an early knee osteoarthritis from x-ray images.

16 Dec 2022

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Researchers from the Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered a novel subtype of Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and EBV-associated immunosuppression in the tumor microenvironment (TME).

16 Dec 2022

Medical Condition News

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Research project helps to improve the care of adult refugees suffering from PTSD

NEJM study shows hidden genetic anomaly behind common late-onset cerebellar ataxia

Landmark population health study could pave the way for better tools to fight chronic diseases in Asian populations

New support for a serotonin deficit in depression

High performing primary care practices for patients with diabetes during the pandemic

Study provides new insights into the pathology of LATE

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

Outpatient clinic visits with a nephrologist associated with lower risk of mortality in patients with acute kidney injury

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Study: People with cluster headaches may be more likely to have other medical conditions

AI-based neural network can detect early knee osteoarthritis from x-ray images

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Changing heart cell programming can reverse the lasting damage caused by heart attacks

Experimental therapy shows promise as treatment for metastatic colon cancer in preclinical models

Researchers identify a new target gene in pancreatic ductal adenocarcinoma

Activated vitamin D3 inhibits arsenic-mediated carcinogenesis in certain skin cells, research shows

Study uncovers new immune target to treat atherosclerosis

BMI decline patterns may predict a person's risk for dementia

Incidence of Parkinson's disease among older adults is 50% higher than current estimates, study reveals

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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