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Vague, superficial advice given by doctors to patients living with obesity

A new research study published today in Family Practice, published by Oxford University Press, finds that when doctors tell patients living with obesity to lose weight the guidance they give is generally vague, superficial, and commonly not supported by scientific evidence.

13 Dec 2022

Targeted therapies and novel drug combinations show promise for the treatment of multiple leukemias

Researchers from The University of Texas MD Anderson Cancer Center are presenting compelling findings from three clinical trials at the 2022 American Society of Hematology Annual Meeting.

13 Dec 2022

Individuals with depression less likely to adhere to medications following percutaneous coronary intervention

Patients diagnosed with depression were less likely to adhere to essential medical therapies following percutaneous coronary intervention (PCI) than those without depression, according to a new study published in JAMA Network Open by researchers at the University of Pittsburgh School of Medicine.

12 Dec 2022

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

Amyloid plaques — protein clumps that are one of the hallmarks of Alzheimer's disease—occur at roughly the same level in the brains of people with Down syndrome who have Alzheimer's as they do in people with forms of hereditary, early-onset Alzheimer's, according to research funded by the National Institutes of Health.

12 Dec 2022

Study of stroke survivors shows how chronic pain can alter body perception

A world-first study of stroke survivors shows how chronic pain can alter body perception, with the brain tricking patients into believing their affected hand is a different size, increasing the risk of accidents.

12 Dec 2022

COVID-19 vaccination temporarily alters heart rate variability

HRV parameters after COVID-19 vaccination show significant short-term changes that may persist for up to three days until ultimately returning to baseline.

12 Dec 2022

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Immunogenicity of SARS-CoV-2 antibody response in immune naïve children and adults

Researchers compare the contribution of antibodies against the SARS-CoV-2 receptor binding domain in vaccinated and naturally infected adults and children.

12 Dec 2022

Study: Only 30% of people with neuroendocrine tumors consider living longer as top priority

New research from cancer research and treatment organization City of Hope in the December 2022 issue of JNCCN - Journal of the National Comprehensive Cancer Network finds that only 30% of patients with advanced neuroendocrine tumors (NETs) say their top goal for treatment is living longer.

12 Dec 2022

Researchers show link between a debilitating heart condition and COVID-19 infection, vaccination

Investigators from the Smidt Heart Institute at Cedars-Sinai validated the link between a debilitating heart condition and COVID-19 and, to a lesser extent, a novel link between the same condition and COVID-19 vaccination.

12 Dec 2022

Light therapy could be a promising non-drug treatment option for multiple sclerosis-related fatigue

Multiple Sclerosis (MS) is almost always accompanied by fatigue, a massive tiredness that is described by the vast majority of patients as the most distressing symptom.

12 Dec 2022

Novel wearable device can monitor physiological parameters associated with heart failure in real-time

There are about 64 million cases of heart failure worldwide. According to the American Heart Association, 6.2 million adults in the United States have heart failure and that number is estimated to increase to 8 million by 2030.

12 Dec 2022

Exposure to extremely hot or cold temperatures increases heart disease deaths

Exposure to extremely hot or cold temperatures increases a heart disease patient's risk of dying, according to a new study published today in the American Heart Association's journal Circulation.

12 Dec 2022

Novel drug shows early potential in combating multiple myeloma

A first-of-its-kind drug known as modakafusp alfa has shown early potential in combating multiple myeloma, a form of bone marrow cancer, in a study presented by researchers from the University of Pennsylvania's Abramson Cancer Center at the 2022 American Society of Hematology Annual Meeting (Abstract 565).

12 Dec 2022

Simplified treatment regimen results in dramatic decrease in early deaths from acute promyelocytic leukemia

The use of a simplified treatment regimen by oncologists, along with management recommendations and 24/7 support provided by a limited and dedicated group of academic disease experts, resulted in a dramatic decrease in early deaths from acute promyelocytic leukemia (APL).

12 Dec 2022

Many genetic disorders respond well to specialized gene therapy

When the normal DNA sequence in an individual changes or mutates it can cause disease. The mutation may involve multiple genes and may be caused by environmental factors, or there may be chromosomal defects that are harmful at birth, in infancy or environment at a later stage.

12 Dec 2022

Study provides new insights for the future development of oral insulin pill

WEHI researchers in Melbourne have answered a 100-year-old question in diabetes research: can a molecule different to insulin have the same effect? The findings provide important insights for the future development of an oral insulin pill.

12 Dec 2022

Novel monoclonal antibody therapy shows promising results in patients with moderate to severe atopic dermatitis

Patients with moderate to severe atopic dermatitis who participated in a clinical trial of rocatinlimab - a novel, patient-tailored monoclonal antibody therapy - showed promising results both while taking the drug and up to 20 weeks after the therapy was stopped, Mount Sinai researchers reported in The Lancet.

12 Dec 2022

Three-drug combination highly effective in patients with high-risk forms of chronic lymphocytic leukemia

A three-drug combination that sent chronic lymphocytic leukemia (CLL) into deep remissions in a broad group of patients in a clinical trial is highly effective in patients with high-risk forms of the disease, a new, phase 2 clinical trial led by Dana-Farber Cancer Institute investigators indicates.

12 Dec 2022

$Forxiga (dapagliflozin) approved in Great Britain for symptomatic chronic heat failure across the full spectrum of left ventricular ejection fraction$

Forxiga (dapagliflozin) approved in Great Britain for symptomatic chronic heat failure across the full spectrum of left ventricular ejection fraction

AstraZeneca today announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted a licence extension for dapagliflozin in Great Britain for the treatment of symptomatic chronic heart failure (HF) in patients with HF and a left ventricular ejection fraction (LVEF) >40%, including HF with mildly reduced ejection fraction (HFmrEF) and preserved ejection fraction (HFpEF).

From AstraZeneca 12 Dec 2022

Medical Condition News

Vague, superficial advice given by doctors to patients living with obesity

Targeted therapies and novel drug combinations show promise for the treatment of multiple leukemias

Individuals with depression less likely to adhere to medications following percutaneous coronary intervention

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

Study of stroke survivors shows how chronic pain can alter body perception

COVID-19 vaccination temporarily alters heart rate variability

How human cell atlases provide the missing links between genes, diseases and therapies

Immunogenicity of SARS-CoV-2 antibody response in immune naïve children and adults

Study: Only 30% of people with neuroendocrine tumors consider living longer as top priority

Researchers show link between a debilitating heart condition and COVID-19 infection, vaccination

Light therapy could be a promising non-drug treatment option for multiple sclerosis-related fatigue

Novel wearable device can monitor physiological parameters associated with heart failure in real-time

Exposure to extremely hot or cold temperatures increases heart disease deaths

Novel drug shows early potential in combating multiple myeloma

Simplified treatment regimen results in dramatic decrease in early deaths from acute promyelocytic leukemia

Many genetic disorders respond well to specialized gene therapy

Study provides new insights for the future development of oral insulin pill

Novel monoclonal antibody therapy shows promising results in patients with moderate to severe atopic dermatitis

Three-drug combination highly effective in patients with high-risk forms of chronic lymphocytic leukemia

Forxiga (dapagliflozin) approved in Great Britain for symptomatic chronic heat failure across the full spectrum of left ventricular ejection fraction

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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