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Extreme heat events may increase risk of hypo- and hyperglycemia–related emergencies

The global effects of climate change have been demonstrated to extend beyond the environment to many other areas including human health, particularly with respect to different health conditions.

12 Sep 2022

Long-COVID in adults and Ontario's expected burden

Scientists identify the healthcare requirements for adults with long COVID.

12 Sep 2022

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center.

12 Sep 2022

Most people prefer fecal immunochemical test rather than a colonoscopy, study says

Three-quarters of people prefer to do a fecal immunochemical test (FIT) rather than a colonoscopy for their regular colorectal cancer screening, according to a new Cedars-Sinai study.

12 Sep 2022

New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Obesity can give rise to a variety of health concerns. Nonalcoholic steatohepatitis (NASH) - a type of fatty liver disease that might progress to cancer - is particularly prevalent among obese people.

12 Sep 2022

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Newly released results from the Phase III ADAURA trial reveal that osimertinib yielded a 5.5-year median disease-free survival in the post-surgical treatment of patients with EGFR-mutated lung cancer, and nearly three in four patients treated with adjuvant osimertinib were disease-free at four years.

12 Sep 2022

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Significant improvement in progression-free survival and response rate combined with reduced symptoms and better quality of life are reported as outcomes of a new treatment approach for patients with desmoid tumors, which are benign, but locally aggressive and invasive soft tissue tumors.

12 Sep 2022

Study identifies new therapeutic target against lung adenocarcinoma

The TIMP-1 protein levels in both tissues and blood have been repeatedly associated with a poor prognosis in lung cancers, but its role in this cancer process was, to date, unknown.

12 Sep 2022

A widening gap found in diabetes-related mortality between urban and rural areas in the USA

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) finds that there is a widening gap in diabetes-related mortality between urban and rural areas in the USA, and that reductions in mortality rates seen predominantly in urban areas have been mainly limited to female and older patients while outcomes in male and younger individuals worsened.

12 Sep 2022

Exercise hormone reduces protein levels linked to Parkinson's disease

Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice.

12 Sep 2022

Research could lead to a new therapeutic option for patients with bladder cancer

Mount Sinai researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system.

12 Sep 2022

Study reveals two distinct types of obesity with physiological and molecular differences

A team led by Van Andel Institute scientists has identified two distinct types of obesity with physiological and molecular differences that may have lifelong consequences for health, disease and response to medication.

12 Sep 2022

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

In a new study, researchers developed RK-33, a small molecule inhibitor of DDX3, and evaluated its efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

12 Sep 2022

UQ researchers receive international funding to combat melanoma in US troops

Researchers at The University of Queensland have been awarded international funding to combat an expected escalation of skin cancer cases in US troops who served in Iraq and Afghanistan.

12 Sep 2022

Patients with high-risk melanoma benefit from immunotherapy prior to surgery

Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.

12 Sep 2022

Study shortlists potential drug repurposing candidates to treat symptoms in ASD

Can you teach an old drug new tricks? Although drug treatments for the core symptoms of autism spectrum disorder (ASD) are not currently available, could an existing drug provide a new treatment, even if it previously had no association with ASD? This was the question asked by a new study in the journal Frontiers in Pharmacology. The researchers used a computer model that encompasses proteins involved in ASD and the way they interact.

12 Sep 2022

Novel tests detect common cancer signals across over 50 types of cancer

Cancer doctors, care providers and payers need to get ready for a major shift in early cancer detection that will affect almost every stage of cancer diagnosis and treatment. New data supporting the accuracy of multi-cancer early detection (MCED) blood testing (1), presented at the ESMO Congress 2022, have major implications for future cancer care provision, said Fabrice André, ESMO 2022 Scientific Co-Chair.

12 Sep 2022

Semaglutide appears to be an effective medication for treating obesity, study says

The risk of type 2 diabetes (T2D) is more than halved by weekly injections of new obesity drug semaglutide, according to new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Stockholm, Sweden (19-23 Sept).

12 Sep 2022

Pre-existing psychological distress increases risk of long-COVID

In a recent study published in the Journal of American Medical Association (JAMA) Psychiatry, researchers investigated the association of psychological distress before coronavirus disease 2019 (COVID-19) with the risk of post-acute sequelae of COVID-19 (PASC).

12 Sep 2022

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial.

12 Sep 2022

Medical Condition News

Extreme heat events may increase risk of hypo- and hyperglycemia–related emergencies

Long-COVID in adults and Ontario's expected burden

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

Most people prefer fecal immunochemical test rather than a colonoscopy, study says

New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Study identifies new therapeutic target against lung adenocarcinoma

A widening gap found in diabetes-related mortality between urban and rural areas in the USA

Exercise hormone reduces protein levels linked to Parkinson's disease

Research could lead to a new therapeutic option for patients with bladder cancer

Study reveals two distinct types of obesity with physiological and molecular differences

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

UQ researchers receive international funding to combat melanoma in US troops

Patients with high-risk melanoma benefit from immunotherapy prior to surgery

Study shortlists potential drug repurposing candidates to treat symptoms in ASD

Novel tests detect common cancer signals across over 50 types of cancer

Semaglutide appears to be an effective medication for treating obesity, study says

Pre-existing psychological distress increases risk of long-COVID

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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