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Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Humans are still evolving, and Tatum Simonson, PhD, founder and co-director of the Center for Physiological Genomics of Low Oxygen at University of California School of Medicine, plans to use evolution to improve healthcare for all.

12 Feb 2024

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

Method by which androgen-activated androgen receptors (ARs) increase fucosyltransferase 4 (FUT4) expression.

12 Feb 2024

Pregnant women show significant immune system changes linked to gut microbiome

How gut microbiota and metabolite changes relate to immune function during pregnancy.

12 Feb 2024

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

A study in eBioMedicine identifies genetic factors regulating blood estrone levels in postmenopausal women, linking specific genetic loci to an increased risk of endometrial cancer, highlighting the role of non-ovarian estrogen production in cancer development.

11 Feb 2024

Stress driving substance use in American teens, study finds

A study in the Morbidity and Mortality Weekly Report reveals stress and experimentation as primary motivators for substance use among American adolescents, with significant implications for developing targeted interventions and educational programs.

11 Feb 2024

Long COVID in children: A closer look reveals lasting impacts

A comprehensive review in Pediatrics highlights the significant impact of post-acute sequelae of SARS-CoV-2 (PASC) in children, revealing a wide range of long-term symptoms and the need for further research on its prevalence, risk factors, and mechanisms.

11 Feb 2024

Drug repurposing study finds lonafarnib effective against RSV

A study in Nature Communications identifies lonafarnib from the ReFRAME drug-repurposing library as a potent inhibitor of the RSV fusion protein, showing promise in reducing RSV infection in vitro and in vivo.

11 Feb 2024

Prenatal exposure to phthalates linked to higher risk of preterm birth and low birth weight

Research in The Lancet Planetary Health links prenatal phthalate exposure to increased risks of preterm birth and low birth weight, underscoring the need for regulatory oversight on chemicals used in consumer products.

11 Feb 2024

Nutrition labels lead to healthier eating in teens, study finds

Study finds that middle and high school students in Texas who use nutrition labels tend to have healthier eating habits, highlighting the importance of nutrition literacy in promoting better dietary choices among adolescents.

11 Feb 2024

New study finds 4’-fluorouridine effective against avian influenza in vitro and in vivo

A PLOS Pathogens study reveals 4’-fluorouridine effectively combats avian influenza in vitro and in animal models, showing promise as a treatment that overcomes resistance and reduces disease severity without significant adverse effects.

11 Feb 2024

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

UNC School of Medicine researcher Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE) – the biggest genetic risk factor for late-onset Alzheimer's disease.

9 Feb 2024

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis."

9 Feb 2024

Blocking artery plus surgery offers hope for reducing reoperations in brain hematoma patients

Injection of a substance to block an artery feeding the dura (protective sack around the brain) along with surgery to remove pooled blood reduced the risk that patients will require repeat surgery compared to surgical drainage alone, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

9 Feb 2024

Robotic and navigation technology in hip surgery don't raise infection risk, study finds

For patients undergoing total hip arthroplasty (THA), the use of robotic-assisted surgery and surgical navigation techniques is not associated with an increased risk of periprosthetic joint infection (PJI), suggests a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio by Wolters Kluwer.

9 Feb 2024

Representation matters to Black patients seeking prostate cancer information online, study shows

For Black men with prostate cancer, racial representation is a key factor affecting trust in websites offering information on prostate cancer, reports a study in the March issue of The Journal of Urology, an Official Journal of the American Urological Association (AUA).

9 Feb 2024

Study shows long COVID's hidden effect on women's sex lives

From work to school to socializing, COVID-19 has impacted just about every part of our lives - and now Boston University research has shown that also includes what happens in the bedroom.

9 Feb 2024

New study shows dramatic health benefits of quitting smoking

People who quit smoking see major gains in life expectancy after just a few years, according to a new study by University of Toronto researchers at Unity Health Toronto.

9 Feb 2024

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

A new research perspective was published in Oncoscience (Volume 11) on February 7, 2024, entitled, "IPIAD- an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma using already-marketed repurposed drugs irbesartan, pyrimethamine, itraconazole, azithromycin, and dapsone."

9 Feb 2024

Immune system in the blood of Alzheimer's patients found to be epigenetically altered

A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients is epigenetically altered.

9 Feb 2024

Understanding the virological properties of SARS-CoV-2 variant JN.1

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a worldwide threat.

9 Feb 2024

Medical Research News

Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

Pregnant women show significant immune system changes linked to gut microbiome

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

Stress driving substance use in American teens, study finds

Long COVID in children: A closer look reveals lasting impacts

Drug repurposing study finds lonafarnib effective against RSV

Prenatal exposure to phthalates linked to higher risk of preterm birth and low birth weight

Nutrition labels lead to healthier eating in teens, study finds

New study finds 4’-fluorouridine effective against avian influenza in vitro and in vivo

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

Blocking artery plus surgery offers hope for reducing reoperations in brain hematoma patients

Robotic and navigation technology in hip surgery don't raise infection risk, study finds

Representation matters to Black patients seeking prostate cancer information online, study shows

Study shows long COVID's hidden effect on women's sex lives

New study shows dramatic health benefits of quitting smoking

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

Immune system in the blood of Alzheimer's patients found to be epigenetically altered

Understanding the virological properties of SARS-CoV-2 variant JN.1

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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