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Study demonstrates successful gene therapy for maple syrup urine disease

A study led by UMass Chan researchers demonstrated that a gene therapy to correct a mutation that causes maple syrup urine disease (MSUD) prevented newborn death, normalized growth, restored coordinated expression of the affected genes and stabilized biomarkers in a calf as well as in mice.

28 Feb 2025

Study identifies barriers to sustaining SNAP-Ed programs in schools

New research reveals significant barriers to sustaining policy, systems, and environmental (PSE) changes in schools through Supplemental Nutrition Assistance Program-Education (SNAP-Ed)-funded partnerships.

28 Feb 2025

Lactylation in the heart reveals key insights into cardiac regeneration

This study is led by Dr. Xiaodong Luan (Institute of Clinical Medicine, Peking Union Medical College Hospital), Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

28 Feb 2025

European project aims to develop new treatments for rare eye diseases

The Ocular Neurobiology laboratory at the Institute for Neurosciences, a joint center of Miguel Hernández University (UMH) in Elche and the Spanish National Research Council (CSIC), is participating in the European project RESTORE VISION, an ambitious initiative aimed at developing new treatments for rare eye diseases such as aniridia and neurotrophic keratopathy.

28 Feb 2025

Review sheds light on the mechanistic role of long non-coding RNAs in liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a global health challenge, affecting nearly 30% of adults worldwide.

28 Feb 2025

Exploring the molecular characteristics of hepatic biliary adenofibroma

Hepatic biliary adenofibroma (BAF) is a rare benign bile duct neoplasm that has garnered increasing attention due to its potential role as a precursor lesion for intrahepatic cholangiocarcinoma (iCCA).

28 Feb 2025

New target identified for preventing cold sores and genital herpes

Scientists have a new target to prevent cold sores after University of Virginia School of Medicine researchers discovered an unexpected way the herpes virus re-activates in the body.

28 Feb 2025

Researchers discover key blood molecules impacting child development

McMaster University researchers have identified small molecules in the blood that may impact early childhood development, showing how dietary exposures, early life experiences, and gut health can influence a child's growth and cognitive milestones.

28 Feb 2025

Researchers make breakthrough in understanding the role of tau protein in Alzheimer's

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease.

28 Feb 2025

Understanding the impact of SLC transporters on liver disease progression

Hepatic steatosis, often triggered by non-alcoholic fatty liver disease (NAFLD), is a leading cause of liver dysfunction globally, affecting approximately 30% of the population.

28 Feb 2025

Widespread E. coli contamination found in Egyptian dairy

No one should have to fear food poisoning every time they eat or drink, but the reality, even in the 21st century, is that risks remain. An Osaka Metropolitan University-led Egypt-Japan research team found E. coli prevalent in over 25% of popular milk and dairy products in Egypt.

28 Feb 2025

Impact of lockdown on stress eating

During the first COVID-19 lockdown, researchers of the University of Vienna assessed the influence of stress, mood, and social interactions on "unhealthy" eating habits in nearly 800 participants across Austria, Italy, and Germany. Surprisingly, results showed that negative mood and less social interactions led to a decrease in "unhealthy" food consumption and enjoyment.

28 Feb 2025

AI detects colorectal cancer with high accuracy

A new AI-based tool for identifying colorectal cancer from tissue sample analysis has been developed at the University of Jyväskylä. The new artificial neural network model has surpassed all its predecessors in classification performance. The tool has also been made freely available.

28 Feb 2025

University of Queensland recognized as the first dementia-friendly university

The University of Queensland has become the first university to be formally recognized by Dementia Australia as a Dementia-Friendly Organization, an initiative that will inform research, raise awareness, reduce stigma and provide a supportive environment.

28 Feb 2025

Hospitalized COVID patients face long-term risks

A nationwide study has revealed that survivors of COVID-19 hospitalization face an increased risk of death or organ-related disorders for up to two-and-a-half years after discharge.

28 Feb 2025

Employee burnout leads to significant financial losses for companies

Employee burnout is likely costing companies millions of dollars each year, ranging from approximately $4,000 to $21,000 per employee in the U.S., according to a study published in the American Journal of Preventive Medicine.

28 Feb 2025

New discovery sheds light on energy crisis in children with TANGO2 deficiency

Researchers studying a protein linked to a rare, severe disease have made a discovery that sheds light on how cells meet their energy needs during a severe metabolic crisis.

28 Feb 2025

Study reveals how air pollution contributes to Alzheimer's disease

Air pollution contributes to nearly 7 million premature deaths each year, and its effects go far beyond the lungs.

28 Feb 2025

UCSF study reveals lungs as source of hematopoietic stem cells

Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing.

28 Feb 2025

Trained immunity may exacerbate inflammatory bone loss disorders

Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, researchers have used their knowledge of the immune system to develop therapies to treat or prevent diseases from influenza to autoimmune disease and cancer.

27 Feb 2025