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Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

To reimagine existing preclinical trials for Alzheimer's disease, University of Pittsburgh School of Medicine neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmoset monkeys, outlining their approach in Alzheimer's & Dementia: Translational Research & Clinical Interventions.

6 Sep 2023

Study reveals heart failure insights at single-cell level

Researchers examined the cell-intrinsic effects of hematopoietic stem cells with somatic mutations in circulating cells from heart failure patients.

6 Sep 2023

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Researchers reviewed the evidence for SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC).

6 Sep 2023

Using ChatGPT to address vaccine hesitancy: a promising tool for guiding users to scientific information?

Researchers assessed ChatGPT's ability to address the 50 most common misconceptions about vaccine safety.

6 Sep 2023

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

Researchers used a SARS-CoV-2 spike protein-pseudotyped viral model to characterize BA.2.86 variant neutralization by monoclonal antibodies.

6 Sep 2023

High dietary intake of added sugars could increase the risk of coronary heart disease

The associations between individual dietary sugar types and the risk of coronary heart disease.

6 Sep 2023

Flash therapy may offer a practical option to delay the circadian clock in shift workers and jet travelers

Researchers examined whether flash therapy, given during sleep, changed the sleep architecture to shift the human circadian clock.

6 Sep 2023

Clovibactin - a game-changing novel antibiotic with no resistance

Researchers reported the discovery of a new antibiotic, clovibactin.

6 Sep 2023

Does dahlia flower extract have anti-diabetic properties?

The effects of an extract of yellow petals of Dahlia pinnata as a novel treatment of type 2 diabetes (T2D).

6 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

Study identifies potential target for reversing drug resistance in ovarian cancer

For the 314,000 people diagnosed with ovarian cancer each year, hope often comes in the form of platinum-based drugs such as cisplatin.

5 Sep 2023

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

New U.S. study finds mRNA-1273.815, a monovalent vaccine targeting the Omicron XBB.1.5 variant, generates higher neutralizing antibody titers compared to its bivalent counterpart. The study supports updating to an XBB.1.5-based monovalent vaccine for the 2023-24 campaign to combat emerging variants.

5 Sep 2023

Researchers receive $2.5 million award to develop a tailored treatment for glioblastoma

A multidisciplinary team of investigators from the UCLA Jonsson Comprehensive Cancer Center was awarded a $2.5 million Translational Team Science Award from the Department of Defense to develop a tailored treatment for glioblastoma, a deadly brain tumor with limited treatment options.

5 Sep 2023

Nursing homes more likely to report workplace injuries and illnesses after unionization

Nursing homes that unionize are more likely to report workplace injury and illness data to the Occupational Safety and Health Administration, a new study published today in the journal Health Affairs says.

5 Sep 2023

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

The study reveals that Novavax's updated XBB.1.5 vaccine effectively induces cross-neutralizing antibodies against multiple Omicron XBB sub-variants in both mice and non-human primates.

5 Sep 2023

Cholesterol crystals linked to diabetic retinopathy

Advancements that could lead to earlier diagnosis and treatment for diabetic retinopathy, a common complication that affects the eyes, have been identified by a multi-department research team from Michigan State and other universities.

5 Sep 2023

ADHD linked to risk for several common and serious mental health issues

The hyperactivity disorder, usually referred to as ADHD, is an independent risk factor for several common and serious mental health issues, finds research published in the open access journal BMJ Mental Health.

5 Sep 2023

Could a new framework for aging biomarkers revolutionize how we understand and treat the aging process?

A comprehensive review in the journal Cell outlines a unified framework for classifying and validating aging biomarkers, aiming to streamline their integration into clinical research and practice. The study categorizes biomarkers into types like molecular, functional, and clinical, and sets criteria for their feasibility, validity, and applicability, all with the goal of better understanding and intervening in the aging process.

5 Sep 2023

Study supports vaccination for COVID-19 in patients with glomerular diseases

Among 2,055 adults with a wide range of glomerular diseases, the COVID-19 vaccination did not adversely affect kidney function or worsen kidney damage and appeared safe in this population.

5 Sep 2023

Could medicinal plants be the key to reversing cognitive decline?

Researchers explore available evidence that medicinal plants may help improve cognitive function by reducing brain inflammation.

5 Sep 2023

Medical Research News

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

Study reveals heart failure insights at single-cell level

Review identifies future research directions for the study of a SARS-CoV-2 reservoir in PASC

Using ChatGPT to address vaccine hesitancy: a promising tool for guiding users to scientific information?

Researchers characterize new SARS-CoV-2 BA.2.86 variant neutralization by monoclonal antibodies

High dietary intake of added sugars could increase the risk of coronary heart disease

Flash therapy may offer a practical option to delay the circadian clock in shift workers and jet travelers

Clovibactin - a game-changing novel antibiotic with no resistance

Does dahlia flower extract have anti-diabetic properties?

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Study identifies potential target for reversing drug resistance in ovarian cancer

Monovalent vaccine outperforms bivalent in fighting new Omicron variants

Researchers receive $2.5 million award to develop a tailored treatment for glioblastoma

Nursing homes more likely to report workplace injuries and illnesses after unionization

Novavax's updated XBB.1.5 vaccine shows promising cross-neutralizing antibodies against new COVID-19 variants

Cholesterol crystals linked to diabetic retinopathy

ADHD linked to risk for several common and serious mental health issues

Could a new framework for aging biomarkers revolutionize how we understand and treat the aging process?

Study supports vaccination for COVID-19 in patients with glomerular diseases

Could medicinal plants be the key to reversing cognitive decline?

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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