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Expert work group examines and redefines “clinical meaningfulness” in Alzheimer’s

As the Alzheimer's disease scientific community, patients, and families seek to understand the results of clinical trials of new Alzheimer's treatments, the Alzheimer's Association convened an expert work group to discuss an important and timely issue: the "clinical meaningfulness" of results from these studies.

7 Feb 2023

Men with low sexual desire might benefit from kisspeptin

A new study in the journal JAMA Network Open aimed to analyze the mechanistic and clinical effects of the administration of kisspeptin in men with HSDD.

7 Feb 2023

Research uncovers brain structural differences in conduct disordered youths with and without maltreatment

Characterized by antisocial behaviors and low academic achievement, conduct disorder (CD) impacts an estimated 9.5% of individuals in the United States.

7 Feb 2023

A waning outbreak of the mpox virus among men who have sex with men

In a recent study posted to the medRxiv* server, researchers developed a mathematical model to describe the mpox (Monkeypox) transmission among men who have sex with men (MSM). They used this model to understand how MSM behavioral changes shaped the mpox outbreak in the Netherlands in June/July 2022.

7 Feb 2023

Researchers highlight the dysregulation of hepatokines in people with NAFLD

Non-alcoholic fatty liver disease (NAFLD) is an important risk factor for type 2 diabetes and cardiovascular diseases.

7 Feb 2023

Study finds distinct differences in how the brain releases dopamine in patients with alcohol use disorder

Dopamine is a neurotransmitter that's made in the brain and acts as a chemical messenger, communicating between nerve cells in the brain and the rest of the body.

7 Feb 2023

Study examines postpartum women's experiences during the third wave of COVID-19

In a recent study published in the journal Pharmacoepidemiology, researchers investigated postpartum women’s birth-associated experiences during the third wave of the coronavirus disease 2019 (COVID-19) pandemic in Europe.

7 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

An approach to review SARS-CoV-2 and Strongyloides stercoralis coinfections

Researchers present the protocol for their systematic review on SARS-CoV-2 and Strongyloides stercoralis coinfections.

7 Feb 2023

A review of innate immunity relevant to SARS-CoV-2 and COVID-19

In a recent study published in The New England Journal of Medicine, researchers reviewed selected acute-phase proteins concerning their production, structure, and function.

7 Feb 2023

Scientists discover new way to reduce progression of diabetic kidney disease

A new way to reduce progression of diabetic kidney disease, affecting 40% of people with diabetes, has been discovered by scientists.

7 Feb 2023

Do individuals with long COVID ever recover fully?

Researchers investigate the sociodemographic factors that contribute to the remission of long COVID.

7 Feb 2023

UC researcher aims to develop better treatments for KRAS-mutated pancreatic cancer

Pancreatic cancer diagnoses are increasing more rapidly than any other cancer type while remaining one of the most deadly cancers.

7 Feb 2023

IU School of Medicine researchers secure grant to study new treatment method for traumatic brain injury

Indiana University School of Medicine and National Intrepid Center of Excellence (NICoE) researchers are collaborating to study a new treatment method for traumatic brain injury (TBI) thanks to a grant from the United States Department of Defense, Congressionally Directed Medical Research Programs (CDMRP).

7 Feb 2023

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers analyzed data from the Increasing Community Access to Testing (ICATT), a nationwide pharmacy program run in the US for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

7 Feb 2023