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Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

In a recent study posted to the medRxiv* preprint server, researchers in Canada evaluated nirmatrelvir and ritonavir (Paxlovid) effectiveness against severe coronavirus disease 2019 (COVID-19) during the dominance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and Omicron sub-VOCs in Canada.

7 Nov 2022

Study helps to justify the use of Ayres Sensory Integration as a tool for autistic children

People with autism are often portrayed in popular media as experiencing difficulty processing highly stimulating or overly loud environments.

7 Nov 2022

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Ramping up medication doses quickly after being hospitalized for acute heart failure resulted in a lower risk of dying or being readmitted for heart failure within the first six months after discharge, compared to usual care, according to a featured science research presentation today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Study identifies a subset of melanoma patients with very low risk of death

Although melanoma is the most serious type of skin cancer, most patients have high chances of surviving the disease.

7 Nov 2022

Vaccine confidence declined significantly since the start of the pandemic, study suggests

A new study suggests that, despite the success of the COVID-19 vaccination campaigns, vaccine confidence has declined significantly since the start of the pandemic.

7 Nov 2022

Combining chemotherapy with an inflammation inhibitor can prevent breast cancer metastasis

A new treatment developed at Tel Aviv University may significantly enhance the efficacy of chemotherapy in breast cancer patients, reducing the risk for lung metastasis following chemo from 52% to only 6%.

7 Nov 2022

Microscopic IBD inflammation linked to women's elevated risk of giving birth preterm

Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a University of Gothenburg study shows.

7 Nov 2022

Paxlovid antiviral therapy reduces risk of long COVID

In a recent study posted to the medRxiv* server, researchers in Saint Louis, Missouri, examined whether nirmatrelvir treatment reduced the risk of long COVID, the disease encompassing the post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [PASC].

7 Nov 2022

Researchers identify gene expression correlated with response to chemotherapy in medulloblastomas

An international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expression is tightly correlated with response to chemotherapy in medulloblastomas, a highly malignant brain tumor affecting pediatric, adolescent, and young adult populations.

7 Nov 2022

New analysis finds significant disparities in the treatment of familial hypercholesterolemia

The Family Heart Foundation, a leading research and advocacy organization, shared results from an analysis of its large U.S. Family Heart DatabaseTM showing significant disparities exist in the treatment of familial hypercholesterolemia (FH) among racial groups, and by income and education levels.

7 Nov 2022

Study reveals the extent of aggression towards caregivers in Parkinson's disease

Caregivers already dealing with the stress of looking after a loved one diagnosed with Parkinson's disease often have another concern to contend with - aggressive behavior directed toward them from the Parkinson's patient.

7 Nov 2022

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Researchers used whole genome sequencing to evaluate monkeypox virus samples from Washington and Ohio states in the United States and identified 25 samples with open reading frame (ORF)-disrupting mutations.

7 Nov 2022

Crowded emergency departments linked with higher rates of death throughout the hospital

Prior research has established that crowding in emergency departments can lead to worse outcomes for patients receiving emergency care.

7 Nov 2022

SARS-CoV-2 activates NLRP3 inflammasome

Researchers assessed the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation.

7 Nov 2022

Open bypass surgery results in better outcomes for specific patients with severe form of peripheral artery disease

Performing open bypass surgery to restore circulation for people with a severe form of peripheral artery disease (PAD) – a condition that limits blood flow to the legs and feet – resulted in better outcomes for specific patients compared to a less-invasive procedure, a National Institutes of Health-supported clinical research trial has found.

7 Nov 2022

Exercise program improves insulin action in the brain

If the brain no longer responds correctly to the hormone insulin (insulin resistance), this also has a negative effect on the metabolism in the body and the regulation of eating behavior.

7 Nov 2022

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Researchers explored the genetic variability among the monkeypox virus genomes of Clade IIb lineage B.1 using a phylodynamic and genetic survey to confirm the epidemic cluster in the clade and understand the evolution of the virus.

7 Nov 2022

Multinational consensus to end COVID-19 pandemic

A new study recommended specific actions to end the coronavirus disease 2019 (COVID-19) pandemic.

7 Nov 2022

Evaluating dual direct-acting antivirals against persistent COVID-19

Researchers assessed the efficiency of dual direct-acting antivirals in treating persistent coronavirus disease 2019 (COVID-19).

7 Nov 2022

Increased consumption of ultraprocessed foods associated with premature, preventable deaths

Ultraprocessed foods (UPFs), ready-to-eat-or-heat industrial formulations made with ingredients extracted from foods or synthesized in laboratories, have gradually been replacing traditional foods and meals made from fresh and minimally processed ingredients in many countries.

7 Nov 2022

Medical Research News

Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

Study helps to justify the use of Ayres Sensory Integration as a tool for autistic children

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Study identifies a subset of melanoma patients with very low risk of death

Vaccine confidence declined significantly since the start of the pandemic, study suggests

Combining chemotherapy with an inflammation inhibitor can prevent breast cancer metastasis

Microscopic IBD inflammation linked to women's elevated risk of giving birth preterm

Paxlovid antiviral therapy reduces risk of long COVID

Researchers identify gene expression correlated with response to chemotherapy in medulloblastomas

New analysis finds significant disparities in the treatment of familial hypercholesterolemia

Study reveals the extent of aggression towards caregivers in Parkinson's disease

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Crowded emergency departments linked with higher rates of death throughout the hospital

SARS-CoV-2 activates NLRP3 inflammasome

Open bypass surgery results in better outcomes for specific patients with severe form of peripheral artery disease

Exercise program improves insulin action in the brain

Phylodynamic analysis of the monkeypox virus genome suggests low genetic variation and evolutionary rates

Multinational consensus to end COVID-19 pandemic

Evaluating dual direct-acting antivirals against persistent COVID-19

Increased consumption of ultraprocessed foods associated with premature, preventable deaths

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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