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Breakthrough infection risk and immune responses to vaccines associated with human leukocyte antigen alleles

Researchers from the U.K. used data from clinical trials of the Oxford-AstraZeneca COVID-19 vaccine ChAdOx1 nCoV-19 to understand the genetic factors contributing to the individual variations in the antibody responses to the vaccine.

20 Oct 2022

Investigating increased healthcare usage after SARS-CoV-2 infection

In a new study, researchers evaluated the post-acute burden of healthcare use after SARS-CoV-2 infection in adults.

20 Oct 2022

Two small molecules reverse pancreatic acinar ductal metaplasia

Pancreatic cancer often lurks as a silent disease. With no known symptoms, it can progress undetected and spread to other organs.

20 Oct 2022

Shopping vouchers aid in cessation of smoking among pregnant women

The offer of up to £400 of shopping vouchers to stop smoking during pregnancy as an addition to usual stop smoking support is highly effective, finds a trial published by The BMJ today.

20 Oct 2022

Depression risk increases with number of hours worked in stressful jobs

The more hours someone works each week in a stressful job, the more their risk of depression rises, a study in new doctors finds.

20 Oct 2022

11 key measures for monitoring clinical activity during COVID-19

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom described key measurements for monitoring clinical activity during the coronavirus disease 2019 (COVID-19) pandemic.

20 Oct 2022

Study shows increased risks of death in offspring born to mothers with hypertensive disorder of pregnancy

A disorder that can trigger abnormally high blood pressure in pregnancy is associated with increased risks of death in offspring from birth to young adulthood, finds a study published by The BMJ today.

20 Oct 2022

Research uncovers mechanisms governing SARS-CoV-2 Omicron subvariant entry

In a recent study posted to the bioRxiv* preprint server, researchers at Ohio State University and the University of Texas Medical Branch assessed the underlying mechanisms involved in the fusogenicity and endosomal entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants.

20 Oct 2022

When COVID-19 hit, life expectancy plummeted worldwide

In a recent study published in the journal Nature Human Behavior, researchers estimated life expectancy (LE) changes in 29 high- and middle-income countries since 2020, when the coronavirus disease 2019 (COVID-19) pandemic began.

20 Oct 2022

Link between shorter sleep in later life and multiple diseases

Human physiological processes rely heavily on sleep for proper functioning. A recent PLOS Medicine journal study determined the relationship between sleep duration of older people, i.e., 50, 60, and 70 years of age, and the incidence of multimorbidity. Significantly, the study utilized follow-up data for twenty-five years for the analysis.

19 Oct 2022

Why do some people attract mosquitoes more than others?

Mosquitoes (e.g., Aedes aegypti) are common vectors for many viruses that infect the human population, such as dengue, Zika, and yellow fever.

19 Oct 2022

Study shows low risk of myocarditis/pericarditis after mRNA COVID-19 vaccination

Scientists determine the risk of myocarditis and pericarditis among young individuals who have received mRNA-based COVID-19 vaccines.

19 Oct 2022

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

A recent study investigates poorer vaccine responses observed in the elderly following receipt of a COVID-19 booster vaccination dose.

19 Oct 2022

Licorice root extract shows potential as a COVID-19 treatment

A recent study explores the activity of glycyrrhizin against SARS-CoV-2.

19 Oct 2022

SARS-CoV-2 transmission from infected owner to pet rats

SARS-CoV-2 Omicron transmission from a symptomatically infected individual to two domestic rats.

19 Oct 2022

Weight change in the early stages of Parkinson's disease may be linked with changes in thinking skills

People who gain or lose weight soon after being diagnosed with Parkinson's disease may be more likely to have changes in their thinking skills than people who maintain their weight, according to a study published in the October 19, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Oct 2022

Study shows how brain's sensitivity to regret may be altered in mood disorders

Researchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regret may be linked to an individual's ability to cope with stress, and altered in psychiatric disorders like depression.

19 Oct 2022

PC-CARE offers notable benefits to children and caregivers in seven weeks, study shows

Only about 25 percent of children with challenging behaviors receive mental health treatment, and dropout rates are high for those who do.

19 Oct 2022

Immune-suppressing drug reverses symptoms of delirium in mice

Investigators from the departments of Neurology, Neurosurgery, Psychiatry, Medicine, and Biomedical Sciences at Cedars-Sinai have shown that an immune-suppressing drug similar to one used to treat severe COVID-19 reversed symptoms of delirium in mice whose lungs were injured during mechanical breathing assistance.

19 Oct 2022

Study provides unique picture of blood sugar dynamics and autoimmunity in early childhood

When and why does type 1 diabetes manifest in children? For the first time, researchers conducted a long-term study on infants and young children with increased genetic risk of type 1 diabetes.

19 Oct 2022