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New insight into how childhood traumas affect health outcomes

The social environments we grow up in are critical when determining our wellbeing and health later in life. Most Americans (67%) report experiencing at least one traumatic event in childhood, and a new study shows that these experiences have significant impacts on our health risks as adults.

8 Nov 2022

Pediatric deaths due to COVID-19 remain very low, study shows

A new study conducted in England shows that the risk of death due to COVID-19 remains very low for children and young people, and most deaths occur in those with underlying health conditions.

8 Nov 2022

Scientists determine 5,072 essential human genes

In a recent study published in the journal Cell, researchers examined the phenotypic landscape of multiple elusive essential human genes to create a detailed genotype-phenotype resource outlining the phenotypic consequences of disrupting fundamental cellular processes.

8 Nov 2022

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

In a recent study published in the journal Cell Host & Microbe, researchers pursued novel approaches that could help find monoclonal antibodies (mAbs) broadly targeting coronaviruses (CoVs), especially genera beta CoVs.

8 Nov 2022

Cell competition could be responsible for cancer relapses, study shows

A normal process called cell competition, in which healthy tissues eliminate unhealthy cells, could be responsible for cancer relapses in patients months or years after they were declared cancer-free, a new study by UT Southwestern Simmons Cancer Center researchers suggests.

8 Nov 2022

Curbing depression among parents improves control of children's asthma, study finds

Depression and anxiety in the parents of children with asthma have been associated with increased clinic visits and asthma-related hospitalizations.

8 Nov 2022

Skipping methotrexate for one week after flu vaccine provides the same seroprotection as a two-week hold in RA patients

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed that discontinuing methotrexate for one week after seasonal influenza vaccination provided the same seroprotection as a two-week discontinuation period in patients with rheumatoid arthritis.

8 Nov 2022

Combination treatment does not slow radiographic spinal progression in radiographic axSpA patients

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed that combining a nonsteroidal anti-inflammatory drug and TNF inhibitor did not significantly slow radiographic spinal progression in radiographic axial spondyloarthritis patients.

8 Nov 2022

Lower hydroxychloroquine dosing results in increased SLE-related hospitalizations, study finds

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual scientific meeting, found that the recommended weight-based or non-weight-based dose of hydroxychloroquine led to more hospitalizations for flares among patients with systemic lupus erythematosus

8 Nov 2022

Study identifies novel inhibitors against SARS-CoV-2 main protease

In a recent study posted to the bioRxiv* server, researchers at the University of Arizona screened ~11 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro)-inhibiting small compounds in the ZINC15 database using a structure-based in-silico screening method.

8 Nov 2022

Spine disease in CRMO patients found to be more common than previously believed

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, shows that spine disease, once considered a rarity in chronic recurrent multifocal osteomyelitis, affects as many as 10-35% of patients and is asymptomatic in one-third.

8 Nov 2022

Study: No significant difference in cancer risk in rheumatology patients with history of malignancy taking DMARDs

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, found no significant difference in cancer risk in patients with rheumatic disease and a history of malignancy taking biologic or targeted synthetic DMARDs compared to those treated with TNF inhibitors.

8 Nov 2022

Rheumatoid arthritis patients taking opioids have twice the risk of venous thromboembolism

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, found that adult RA patients starting opioids had twice the risk of venous thromboembolism (VTE) compared to patients starting nonsteroidal anti-inflammatory drugs (NSAIDs).

8 Nov 2022

New evidence of a critical neuroplasticity period in the frontal brain during adolescence

In a paper published in Progress in Neurobiology, University of Pittsburgh School of Medicine neuroscientists described compelling new evidence of a critical neuroplasticity period in the frontal brain region during adolescence, a time when major mental illnesses such as depression and schizophrenia emerge and risk-taking behavior peaks.

8 Nov 2022

New breakthrough could help spot lung cancer earlier and improve patient outcomes

Scientists investigating the mechanics of the early stages of lung cancer have identified a new potential treatment, which could also aid early detection of the disease.

8 Nov 2022

New urine tests for early diagnosis of chronic kidney disease

Early diagnosis of chronic kidney disease (CKD) is key to managing progression of the disease. A new technique analyzing urine extracellular vesicles (uEVs) - cell-derived nanoscale spherical structures involved in multiple biological functions - in urine samples identifies changes in the kidneys earlier than conventional methods and can also predict renal function decline.

8 Nov 2022

Medical Research News

New insight into how childhood traumas affect health outcomes

Pediatric deaths due to COVID-19 remain very low, study shows

Scientists determine 5,072 essential human genes

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

Cell competition could be responsible for cancer relapses, study shows

Curbing depression among parents improves control of children's asthma, study finds

Skipping methotrexate for one week after flu vaccine provides the same seroprotection as a two-week hold in RA patients

Combination treatment does not slow radiographic spinal progression in radiographic axSpA patients

Lower hydroxychloroquine dosing results in increased SLE-related hospitalizations, study finds

Study identifies novel inhibitors against SARS-CoV-2 main protease

Spine disease in CRMO patients found to be more common than previously believed

Study: No significant difference in cancer risk in rheumatology patients with history of malignancy taking DMARDs

Rheumatoid arthritis patients taking opioids have twice the risk of venous thromboembolism

New evidence of a critical neuroplasticity period in the frontal brain during adolescence

New breakthrough could help spot lung cancer earlier and improve patient outcomes

New urine tests for early diagnosis of chronic kidney disease

New research helps understand how breathing shapes our brain

Annual global death toll from fine particulate outdoor air pollution may be higher than previously thought

UQ researchers discover a link between obstructive sleep apnea and dementia

Researchers discover neuronal mechanism involved in the learning of maternal behavior

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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