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Study finds increased risk for SARS-CoV-2 breakthrough infections in people with substance use disorders

An analysis of electronic health records of nearly 580,000 fully vaccinated people in the United States found that the risk of SARS-CoV-2 breakthrough infection among vaccinated patients with substance use disorders was low overall, but higher than the risk among vaccinated people without substance use disorders.

6 Oct 2021

Researchers capture mechanisms for predicting cartilage degradation and recovery after ACL injury

Post-traumatic osteoarthritis is a musculoskeletal disorder shadowing especially the life of young and active population.

6 Oct 2021

Gene expression changes during acute SARS-CoV-2 infection may decide long-COVID symptoms

A team of US-based scientists has recently revealed the changes in gene expression profiles associated with the long-term consequences of COVID-19.

6 Oct 2021

Enisamium shows potential as antiviral therapy for COVID-19

Researchers studied the effect of enisamium on the growth and proliferation of Caco-2 and normal human bronchial epithelial cells.

6 Oct 2021

Exposure to air pollution and traffic noise over time may increase risk of developing heart failure

Exposure to air pollution and road traffic noise over the course of many years may be associated with an increased risk of developing heart failure, and the correlation appears to be even greater in people who are former smokers or have high blood pressure, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

6 Oct 2021

Study shows strong protective effect of IgG3 antibodies in SARS-CoV-2 infection

Researchers published a study on the expression and functional analyses of a neutralizing mAb with identical variable domains but different constant HCs, representing IgG1-4.

6 Oct 2021

Rapid molecular assay to detect SARS-CoV-2-specific RNA sequences

The study reported rapid detection of SARS-CoV-2 with high sensitivity and specificity in clinical samples.

6 Oct 2021

Transmission of SARS-CoV-2 during a 2-hour domestic flight

A new study investigated a cluster of COVID-19 infections among travelers who were likely exposed to an index patient in an airplane.

6 Oct 2021

Comparative analysis between the SARS-CoV-1 and SARS-CoV-2 mPro systems

To better understand the biophysical changes that occur due to mutations, the mechanisms of multiple SARS-CoV-2 proteins have been studied and compared with SARS-CoV-1.

6 Oct 2021

SARS-CoV-2 emerging variants display enhanced syncytia formation

Researchers compared the replication and syncytia forming potential of Alpha, Beta, and D614G strains in human cell lines and primary airway cells.

6 Oct 2021

Study shows lower SARS-CoV-2 infection rates in smokers

Coronavirus disease 2019 (COVID-19) primarily infects the lungs, later spreading through the bloodstream. The worst prognoses are mostly seen in ‘at-risk’ groups, such as the immunocompromised, elderly, or those suffering from respiratory conditions.

6 Oct 2021

What is the frequency of COVID testing to prevent Delta variant transmission?

In a new study published on the medRxiv* preprint server, scientists have used available data on the Delta variant’s viral load to infer its infectiousness and, subsequently, estimate the reduction in its transmission brought about by surveillance testing. The testing, done at different frequencies, was performed on a susceptible population. The cases of both the original Wuhan strain and the Delta variant were considered.

6 Oct 2021

Research project receives DOE funding to reduce the size of scientific data sets

The amount of data produced each year by scientific user facilities such as those at national labs or government organizations can range up to several billion gigabytes per year.

6 Oct 2021

New study aims to find early drivers of pulmonary fibrosis in at-risk patient population

Researchers at Vanderbilt University Medical Center are leading a study designed to identify early drivers of pulmonary fibrosis in an at-risk patient population. Funding for the research, which could help predict early disease at the cellular level and possibly drive the development of novel therapies, is being provided by Three Lakes Foundation.

6 Oct 2021

Study provides new insights into how cannabis extracts may work to treat epilepsy

Research from pharmacologists at the University of Sydney provides new insights into how cannabis extracts may work to treat epilepsy.

6 Oct 2021

Autoimmune disease drug helps prevent lung damage, death in mice with SARS-CoV-2 infection

In a new paper, researchers at the University of Illinois Chicago report that a drug approved for treating patients with autoimmune disease helped to prevent lung damage and death in mice infected with the SARS-CoV-2 virus, which causes COVID-19 in humans.

6 Oct 2021

Acute myocarditis extremely rare after COVID mRNA vaccination in adults

Now, a new study published in the journal JAMA Internal Medicine evaluated the incidence of acute myocarditis and clinical outcomes among adults who received the mRNA vaccine in an integrated health care system in the United States.

5 Oct 2021

Neonatal outcomes of preterm infants born during COVID lockdowns in Melbourne, Australia

A team of researchers from Australian institutes examined the consequences of community-wide lockdowns on neonatal outcomes of preterm infants, with a secondary focus on the underlying rates of systemic inflammation in infants and mothers around the time of birth.

5 Oct 2021

Research highlights challenges in utilizing Ct data to guide COVID-19 clinical planning

In a new study, a collaboration of researchers from various institutes described the natural history of SARS-CoV-2 testing, which includes Ct values among patients who had tested positive multiple times, prior to the emergence of VOCs in the vaccine roll-out. In addition, the authors analyze the timescale of positivity and clinical features of the population of patients with prolonged SARS-CoV-2 positivity.

5 Oct 2021

Researchers identify mechanism that can lead to deafness in rare Norrie disease

A team of Mass Eye and Ear Scientists led by Albert Edge, PhD, working with research fellow Yushi Hayashi, MD, PhD, has identified the mechanism that can lead to deafness in the rare syndrome, Norrie disease.

5 Oct 2021

Medical Research News

Study finds increased risk for SARS-CoV-2 breakthrough infections in people with substance use disorders

Researchers capture mechanisms for predicting cartilage degradation and recovery after ACL injury

Gene expression changes during acute SARS-CoV-2 infection may decide long-COVID symptoms

Enisamium shows potential as antiviral therapy for COVID-19

Exposure to air pollution and traffic noise over time may increase risk of developing heart failure

Study shows strong protective effect of IgG3 antibodies in SARS-CoV-2 infection

Rapid molecular assay to detect SARS-CoV-2-specific RNA sequences

Transmission of SARS-CoV-2 during a 2-hour domestic flight

Comparative analysis between the SARS-CoV-1 and SARS-CoV-2 mPro systems

SARS-CoV-2 emerging variants display enhanced syncytia formation

Study shows lower SARS-CoV-2 infection rates in smokers

What is the frequency of COVID testing to prevent Delta variant transmission?

Research project receives DOE funding to reduce the size of scientific data sets

New study aims to find early drivers of pulmonary fibrosis in at-risk patient population

Study provides new insights into how cannabis extracts may work to treat epilepsy

Autoimmune disease drug helps prevent lung damage, death in mice with SARS-CoV-2 infection

Acute myocarditis extremely rare after COVID mRNA vaccination in adults

Neonatal outcomes of preterm infants born during COVID lockdowns in Melbourne, Australia

Research highlights challenges in utilizing Ct data to guide COVID-19 clinical planning

Researchers identify mechanism that can lead to deafness in rare Norrie disease

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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