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SARS-CoV-2 vaccines from Pfizer-BioNTech and AstraZeneca reduce mortality among the elderly

Researchers in the UK have demonstrated the efficacy of the Pfizer-BioNTech and AstraZeneca vaccines against severe acute respiratory virus coronavirus 2 (SARS-CoV-2) at preventing death among older individuals with coronavirus disease 2019 (COVID-19).

20 May 2021

Protein-based vaccines against SARS-CoV-2 may provide advantages over mRNA-based vaccines

Researchers in the UK have developed a protein-based subunit vaccine directed against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could serve as an alternative to the mRNA-based vaccines currently approved for protecting against coronavirus disease 2019 (COVID-19).

20 May 2021

The effects of SARS-CoV-2 vaccination on pregnancy and birth

The severe impact of this infection has given rise to a study by Theiler et al. (2021), which investigated the effects of SARS-CoV-2 vaccination in pregnancy in order to examine the protection it could provide to combat the infection.

19 May 2021

Antithrombotic endothelial dysfunction is prevented by Tie2 activation in severe COVID-19

Researchers from the US recently assessed if severe COVID-19 is linked to procoagulant dysfunction of the endothelium and changes in the Tie2-angiopoietin axis. They assessed circulating endothelial markers in a study cohort of 98 patients with mild, moderate, or severe COVID-19. This study is published on the medRxiv* preprint server.

19 May 2021

Working conditions and non-workplace factors affect COVID-19 mortality in England

Researchers from England recently estimated occupational variations in COVID-19 mortality in England and Wales during 2020 and examined how these differences changed post adjustment for non-workplace factors.

19 May 2021

Human monoclonal antibodies neutralize SARS-CoV-2 in an Fc-independent manner

Researchers from Israel recently isolated a set of SARS-CoV-2 neutralizing monoclonal antibodies from blood samples of patients with severe COVID-19. They were the first to show that transgenic K18-hACE2 mice infected with lethal doses of SARS-CoV-2 can be fully protected by administering antibodies even 3 days after infection

19 May 2021

B.1.1.7 not associated with change in serial interval of COVID-19

With data obtained from the Virus Watch study in England and Wales, researchers found that the serial interval of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is broadly similar to estimates from previous studies and there is no evidence that the B.1.1.7 variant is associated with any change.

19 May 2021

Study may lead to new treatments for a wide range of neurological conditions

New research published today sheds important light on how the production of a key protein in the brain is controlled, which could pave the way for new treatments for a wide range of neurological conditions.

19 May 2021

Potential immunotherapy may improve cognitive and behavioral functions after stroke

Specialized immune cells that accumulate in the brain in the days and weeks after a stroke promote neural functions in mice, pointing to a potential immunotherapy that may boost recovery after the acute injury is over, University of Pittsburgh School of Medicine neurologists found.

19 May 2021

Cognitive, behavioral therapy may produce more significant outcomes for obese people

Quality of life relating to physical and mental health can be a key element in the treatment of obese adults.

19 May 2021

Protein intake is more important than protein source to gain muscle strength and mass

Protein intake is more important than protein source if the goal is to gain muscle strength and mass.

19 May 2021

Potentially inappropriate prescribing linked to functional decline in older adults

Individuals are often prescribed increasing numbers of medications as they age, and while many of these prescriptions are justifiable, some may be inappropriate.

19 May 2021

Researchers use base editing to sustainably lower high LDL cholesterol levels

Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence.

19 May 2021

Six key factors determine medication adherence in people with bipolar disorder

People with bipolar disorder may not take their medication because of side effects, fear of addiction and a preference for alternative treatment - according to research from Norfolk and Suffolk NHS Foundation Trust (NSFT) and the University of East Anglia (UEA).

19 May 2021

Medical Research News

SARS-CoV-2 vaccines from Pfizer-BioNTech and AstraZeneca reduce mortality among the elderly

Protein-based vaccines against SARS-CoV-2 may provide advantages over mRNA-based vaccines

The effects of SARS-CoV-2 vaccination on pregnancy and birth

Antithrombotic endothelial dysfunction is prevented by Tie2 activation in severe COVID-19

Working conditions and non-workplace factors affect COVID-19 mortality in England

Human monoclonal antibodies neutralize SARS-CoV-2 in an Fc-independent manner

B.1.1.7 not associated with change in serial interval of COVID-19

Study may lead to new treatments for a wide range of neurological conditions

Potential immunotherapy may improve cognitive and behavioral functions after stroke

Cognitive, behavioral therapy may produce more significant outcomes for obese people

Protein intake is more important than protein source to gain muscle strength and mass

Potentially inappropriate prescribing linked to functional decline in older adults

Researchers use base editing to sustainably lower high LDL cholesterol levels

Six key factors determine medication adherence in people with bipolar disorder

Exposure to widely used herbicides is significantly associated with preterm births, finds study

Researchers develop integrative approach to better understand the origins of Parkinson's disease

Secondhand smoke during pregnancy linked to epigenetic changes in babies

Children with sleep disordered breathing disorder are likely to show aggressive, hyperactive behaviors

Pfizer/BioNTech COVID-19 vaccine induces a stronger antibody response when given at an extended interval

Virtual analysis identifies a potential natural inhibitor of SARS-CoV-2 Nsp15

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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