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COVID-19 may not have appeared first in China, suggests new genomic study

A new study in Acta Mathematica Scientia suggests that the virus may have originated in multiple countries almost simultaneously, rather than spreading from China to the rest of the world.

3 May 2021

Hopeaphenol inhibits entry of SARS-CoV-2 variants of concern into cells

A new study, released as a preprint on the bioRxiv* server, reports promising results with the natural product hopeaphenol, which successfully prevented the entry of the virus into host cells.

3 May 2021

Class I HLA alleles shape CD8+ T cell repertoire in SARS-CoV-2 infection

An interesting new study discusses how adaptive cellular immunity against the SARS-CoV-2 is dependent on differences in HLA-encoding genes between patients.

3 May 2021

Most long COVID-19 sequelae affect people under 65, finds study

A new study, released as a preprint on the medRxiv* server, discusses the typical symptoms and signs of this syndrome, with the intention of improving the specificity of detection and reporting.

3 May 2021

Discovery opens new avenues for developing antibody-based therapies for malaria

WEHI researchers have identified how natural human antibodies can block malaria parasites from entering red blood cells, potentially indicating how new protective therapies could be developed against this globally significant disease.

3 May 2021

Rutgers study finds higher levels of 'forever chemicals' in volunteer firefighters

Volunteer firefighters -- who comprise more than 65 percent of the U.S. fire service -- have higher levels of "forever chemicals," per- and polyfluoroalkyl substances (PFAS), in their bodies than the general public, according to a Rutgers study.

3 May 2021

Chemotherapy drugs delivered via nanoparticles could improve bowel cancer survival rates

Bowel cancer survival rates could be improved if chemotherapy drugs were delivered via tiny nanoparticles to the diseased organs rather than oral treatment.

3 May 2021

Planned cesarean deliveries may be associated with lower risk of adverse outcomes

New research shows that planned cesarean deliveries on maternal request are safe for low-risk pregnancies and may be associated with a lower risk of adverse delivery outcomes than planned vaginal deliveries.

3 May 2021

A new SARS-CoV-2 variant (HMN.19B) has been identified in France

New research published in the Centers for Disease Control and Prevention’s journal Emerging Infectious Diseases has confirmed the emergence of a new SARS-CoV-2 variant called HMN.19B from the viral clade 19B in France. The 19B viral clade — which includes the D614G variant — was prevalent in late 2019 but had since been rarely observed since early 2020 because of newer viral clades.

3 May 2021

Vaccine candidate targeting SARS-CoV-2 nucleocapsid protein elicits protective immune response in animal model

New preclinical results from a study led by David Masopust of the University of Minnesota in Minneapolis, USA, show that a Had5-based vaccine targeting the nucleocapsid protein can also elicit a protective immune response.

3 May 2021

Competitive multiplex binding assay can monitor SARS-CoV-2 immune responses using nanobodies

Researchers at the Eberhard Karls University and the University of Tübingen in Germany described 11 unique nanobodies (Nbs) specific for the SARS-CoV-2 spike receptor-binding domain (RBD), of which 8 Nbs potentially inhibit the connection of RBD with the angiotensin-converting enzyme 2 (ACE2).

3 May 2021

SARS-CoV-2’s distinctive "spike" protein plays a key role in the disease itself, shows study

Scientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that they also play a key role in the disease itself.

3 May 2021

New gene therapy restores dystrophin protein in patients with Duchenne muscular dystrophy

UT Southwestern scientists successfully employed a new type of gene therapy to treat mice with Duchenne muscular dystrophy (DMD), uniquely utilizing CRISPR-Cas9-based tools to restore a large section of the dystrophin protein that is missing in many DMD patients.

3 May 2021

Pulmonary endarterectomy improves outcomes in patients with segmental disease

A new study, presented today at the AATS 101st Annual Meeting, found that patients treated surgically for segmental Chronic Thromboembolic Pulmonary Hypertension (CTEPH) had excellent outcomes with the vast majority doing very well in the long term without any additional treatment other than surgery.

3 May 2021

Atrial fenestration during atrioventricular septal defect repair is linked to higher mortality rate

A new study, presented today at the AATS 101st Annual Meeting, shows an association between decreased survival at five years and leaving an atrial communication at biventricular repair of unbalanced AVSD after adjusting for other known risk factors.

3 May 2021

Study finds one-third of COVID-19 patients experience neurological symptoms

The research on the short and long-term effects of COVID-19 disease is ongoing. Still, scientists have found severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the brain causing loss of smell and taste, dizziness, muscle pain, fatigue, and other cognitive impairments. However, it remained unknown why certain people developed neurological symptoms while others did not.

3 May 2021

Majority of patients who needed surgery after failed TEER required mitral valve replacement

A new study, presented today at the AATS 101st Annual Meeting, and simultaneously published in the Journal of the American College of Cardiology, finds that patients suffering from severe mitral regurgitation should be carefully screened and counselled before undergoing transcatheter edge-to-edge mitral repair (TEER).

3 May 2021

Low-profile thoracic aortic endograft minimizes complications, increases patient pool

Preliminary results of a clinical trial, presented today at the AATS 101st Annual Meeting, showed that a new, low-profile thoracic aortic endograft is safe and effective in the treatment of descending thoracic aortic aneurysm or penetrating atherosclerotic ulcer (PAU) diseases.

3 May 2021

Study estimates true number of COVID-19 deaths by U.S. county

Every country has been affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has spawned a pandemic. For several factors, the United States has been hit hard by the number of coronavirus cases and death. The country currently leads the world with over 32.4 million infections and more than 577,000 COVID-19 deaths.

3 May 2021

Study quantifies the true incidence of venous thromboembolism post esophagectomy

A new study presented today at the AATS 101st Annual Meeting, found that the percentage of patients undergoing esophagectomy for cancer who suffer Venous Thromboembolism (VTE) post-operatively is much higher than previously reported, with as many as 24 percent suffering from Deep Vein Thrombosis (DVT) or Pulmonary Embolism (PE).

3 May 2021

Medical Research News

COVID-19 may not have appeared first in China, suggests new genomic study

Hopeaphenol inhibits entry of SARS-CoV-2 variants of concern into cells

Class I HLA alleles shape CD8+ T cell repertoire in SARS-CoV-2 infection

Most long COVID-19 sequelae affect people under 65, finds study

Discovery opens new avenues for developing antibody-based therapies for malaria

Rutgers study finds higher levels of 'forever chemicals' in volunteer firefighters

Chemotherapy drugs delivered via nanoparticles could improve bowel cancer survival rates

Planned cesarean deliveries may be associated with lower risk of adverse outcomes

A new SARS-CoV-2 variant (HMN.19B) has been identified in France

Vaccine candidate targeting SARS-CoV-2 nucleocapsid protein elicits protective immune response in animal model

Competitive multiplex binding assay can monitor SARS-CoV-2 immune responses using nanobodies

SARS-CoV-2’s distinctive "spike" protein plays a key role in the disease itself, shows study

New gene therapy restores dystrophin protein in patients with Duchenne muscular dystrophy

Pulmonary endarterectomy improves outcomes in patients with segmental disease

Atrial fenestration during atrioventricular septal defect repair is linked to higher mortality rate

Study finds one-third of COVID-19 patients experience neurological symptoms

Majority of patients who needed surgery after failed TEER required mitral valve replacement

Low-profile thoracic aortic endograft minimizes complications, increases patient pool

Study estimates true number of COVID-19 deaths by U.S. county

Study quantifies the true incidence of venous thromboembolism post esophagectomy

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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