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Bariatric surgery reduces brain pressure in patients with idiopathic intracranial hypertension

Weight loss surgery is more effective than dieting to reduce brain pressure that can cause blindness in patients with a neurological condition, finds a study led by the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust.

26 Apr 2021

Hypoxia radioactive marker will detect aggressiveness of tumors, eliminating the need for biopsy

Scientific advances in cancer research and new means of diagnosis and treatment have made it possible to cure many patients.

26 Apr 2021

Football Fitness improves balance, muscle strength and bone density in women treated for breast cancer

The University of Southern Denmark, Rigshospitalet and the University of Copenhagen have come together to study the effects of Football Fitness on various health parameters and self-rated health following treatment for breast cancer.

26 Apr 2021

Ultraviolet C radiation is effective in inactivating SARS-CoV-2 on glass surfaces, a study finds

A team of scientists from the Texas Biomedical Research Institute and UV Innovators, Inc., USA, recently developed an ultraviolet C radiation emitting device called NuvaWave, which is capable of inactivating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on glass surfaces within seconds.

26 Apr 2021

Researchers characterize India’s devastating second wave of COVID-19

The COVID-19 pandemic continues to take a heavy toll on human health worldwide. The second wave in India has caught everyone by surprise, showing up the total lack of foresight or precautions. With well over 0.2 million deaths in India, and infections raging out of control, a new study predicts 0.35 million daily cases at the peak of the second wave.

26 Apr 2021

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

However, with the waning of the immune response, it is not clear if these older people respond to the vaccine as well as younger individuals do. A recent study explored this question and found that though the antibody levels were somewhat lower in this group, they were still robust. This is a promising observation.

26 Apr 2021

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

A new study deals with the inhibitory activity of a membrane protein that has broad-spectrum activity against multiple viruses, showing that this is due to its effect on cytoplasmic lysine residue incorporation into replicating virions.

26 Apr 2021

Could pooled testing really improve COVID-19 transmission management and decrease costs?

Pooled testing for SARS-CoV-2 detection is instrumental for increasing test capacity while decreasing test cost. A team of researchers at Yale School of the Environment determined the barriers to implementing pooled testing in United States laboratories. The study showed that many laboratories use many instruments in their testing procedures, varying in the number of samples each can process.

26 Apr 2021

Previous SARS-CoV-2 infection associated with more adverse events following mRNA vaccination

The phase 3 trials of the Pfizer and Moderna COVID-19 vaccines did not include those with a known previous SARS-CoV-2 infection. Recent evidence indicates that mRNA vaccines may induce more adverse events in these individuals. In a recent study, 947 individuals, 265 of which have previously reported SARS-CoV-2 infection, were monitored post-vaccination for adverse events, finding that there could be a link between previous infection and greater incidence of these events.

26 Apr 2021

Hormonal therapies for breast and prostate cancers increase the risk of heart attack, stroke

The hormonal therapies used to treat many breast and prostate cancers raise the risk of a heart attack and stroke, and patients should be monitored regularly and receive treatment to reduce risk and detect problems as they occur.

26 Apr 2021

New treatment approach could be life-changing for many stroke patients

Every year, more than 795,000 people in the United States have a stroke. Of these, approximately 80% lose arm function and as many as 50-60% of this population still experience problems six months later.

26 Apr 2021

Cleavage site recognition by SARS-CoV-2 main protease as new antiviral drug target

Many research groups have and are investigating main protease inhibitors as antiviral drugs, and in a paper recently uploaded to the bioRxiv* preprint server, a team of researchers examine the crystal structure of the protein while bound to various viral substrate peptides (P1-4). In doing so, they reveal the way in which the bound peptide sequence can direct and modulate enzyme activity, providing new templates towards antiviral drug design.

26 Apr 2021

Researchers examine potential SARS-CoV-2 antivirals using a drug repurposing library

A new study deals with the screening of the Drug Repurposing Hub (DRH) library for identifying small compounds which are capable of inhibiting SARS-CoV-2 using both in vitro and in vivo experimental studies. These molecules could be used for designing a novel therapeutic system against SARS-CoV-2 infection.

26 Apr 2021

Fighting malaria in 2021: Where are we now and where are we going?

In support of World Malaria Day, News-Medical spoke to Dr. Laurence Slutsker, an internationally recognized expert in malaria, about fighting this disease in 2021.

26 Apr 2021

Experts develop quality indicators for management and outcomes of adults with atrial fibrillation

Management and outcomes of adults with atrial fibrillation are presented today at EHRA 2021, an online scientific congress of the European Society of Cardiology. The document is published in EP Europace, a journal of the ESC.

26 Apr 2021

Single dose of J&J's Ad26.COV2.S vaccine effective against SARS-CoV-2 including in South Africa variant

One of these vaccines, the Ad26.COV2.S vaccine by Johnson & Johnson and Janssen, is a recombinant, replication-incompetent human adenovirus type 26 vector that encodes full-length SARS-CoV-2 spike protein in a prefusion-stabilized conformation.

26 Apr 2021

Using estrogen to target drug-resistant breast cancer in mice

Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) hope to make estrogen therapy a more accessible treatment option for breast cancer patients who could benefit from it.

26 Apr 2021

Real-world study in India finds COVISHIELD vaccine safe and effective

New research led by Naresh Trehan of Medanta-The Medicity in India found the COVISHIELD (ChAdOx1 nCoV-19 Corona Virus Vaccine) vaccine produced an immune response from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) two weeks after vaccination with limited side effects.

26 Apr 2021

SARS-CoV-2 limits type I and type III IFN protein biogenesis

New research led by Roy Parker of the University of Colorado Boulder finds that SARS-CoV-2 prevents the IFN response despite an increased presence of IFN-encoding mRNAs by suppressing transcriptional processes. Inhibition of IFN mRNAs triggers degradation from the activation of RNase L and the SARS-CoV-2 protein Nsp1.

26 Apr 2021

Study: ICD patients should be regularly screened for anxiety and depression

Patients receiving an implantable cardioverter defibrillator (ICD) should be regularly screened for anxiety and depression, according to research presented at EHRA 2021, an online scientific congress of the European Society of Cardiology (ESC)

26 Apr 2021

Medical Research News

Bariatric surgery reduces brain pressure in patients with idiopathic intracranial hypertension

Hypoxia radioactive marker will detect aggressiveness of tumors, eliminating the need for biopsy

Football Fitness improves balance, muscle strength and bone density in women treated for breast cancer

Ultraviolet C radiation is effective in inactivating SARS-CoV-2 on glass surfaces, a study finds

Researchers characterize India’s devastating second wave of COVID-19

SARS-CoV-2 antibody response robust in nursing home residents after Pfizer-BioNTech vaccine

Host cell transmembrane protein MARCH8 targets lysine residues to inhibit SARS-CoV-2 and other viruses

Could pooled testing really improve COVID-19 transmission management and decrease costs?

Previous SARS-CoV-2 infection associated with more adverse events following mRNA vaccination

Hormonal therapies for breast and prostate cancers increase the risk of heart attack, stroke

New treatment approach could be life-changing for many stroke patients

Cleavage site recognition by SARS-CoV-2 main protease as new antiviral drug target

Researchers examine potential SARS-CoV-2 antivirals using a drug repurposing library

Fighting malaria in 2021: Where are we now and where are we going?

Experts develop quality indicators for management and outcomes of adults with atrial fibrillation

Single dose of J&J's Ad26.COV2.S vaccine effective against SARS-CoV-2 including in South Africa variant

Using estrogen to target drug-resistant breast cancer in mice

Real-world study in India finds COVISHIELD vaccine safe and effective

SARS-CoV-2 limits type I and type III IFN protein biogenesis

Study: ICD patients should be regularly screened for anxiety and depression

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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