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Resurgent SARS-CoV-2 infections in England linked to Delta variant

A major factor contributing to the ongoing pandemic of severe acute respiratory coronavirus 2 (SARS-CoV-2) has been the emergence of new variants. Because the mutations of the original virus make variants more transmissible, there is more potential for the contagion to spread through social mixing due to the easing of lockdown.

24 Jun 2021

Internal communication network in mammals provides new insights on obesity, skin disorders

National Institutes of Health scientists and their collaborators have identified an internal communication network in mammals that may regulate tissue repair and inflammation, providing new insights on how diseases such as obesity and inflammatory skin disorders develop. The new research is published in Cell.

24 Jun 2021

Machine-learning approach could accurately predict the evolution of breast cancer

From amoebas to zebras, all living things evolve. They change over time as pressures from the environment cause individuals with certain traits to become more common in a population while those with other traits become less common.

24 Jun 2021

New class of compounds can stop the reproduction of coronavirus

A human genetic mechanism hijacked by SARS-CoV-2, the coronavirus behind the COVID-19 pandemic, to help it spread also makes it vulnerable to a new class of drug candidates, a new study finds.

24 Jun 2021

Biomarker of chronic cellular stress is associated with Huntington's disease, shows study

A new University of California, Irvine-led study finds that the persistence of a marker of chronic cellular stress, previously associated with neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), also takes place in the brains of Huntington's disease (HD) patients.

24 Jun 2021

A study of circulating biomarkers in hospitalized patients infected with SARS-CoV-2 alpha variant

Now, a new study published on the medRxiv* preprint server proposes a rapid method to identify the mutations in B.1.1.7 (N501Y mutation and H69/V70 deletion) and the impact of this variant on various biomarkers in hospitalized patients. This is the first study that correlates the biomarker levels to SARS-CoV-2 variants.

23 Jun 2021

SARS-CoV-2 detection with a simple, inexpensive, and sensitive molecular test

Researchers from the US recently described a rapid molecular test named WHotLAMP for the detection of SARS-CoV-2 in saliva. WHotLAMP is easy to use, very sensitive at 3.6 viral RNA copies per microliter of saliva, specific, and inexpensive. This study is published on the medRxiv*preprint serve.

23 Jun 2021

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

A new analysis of current data indicates that remdesivir does not show efficacy in regulating the severity of the illness.

23 Jun 2021

SARS-CoV-2 Delta variant likely to become dominant in the United States

Researchers have conducted a study showing that the B.1.1.7 lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged in the UK is now rapidly being displaced as the dominant strain in the United States by the variants of concern B.1.617.2 (Delta) and P.1 (Gamma) that emerged in India and Brazil, respectively.

23 Jun 2021

New antibody conjugate delivers drugs to bone tumors and inhibits metastasis

Bone cancer is hard to treat and prone to metastasis. Research teams at Rice University and Baylor College of Medicine have a new strategy to attack it.

23 Jun 2021

Research suggests people living with HIV/AIDS may be less susceptible to SARS-CoV-2

Researchers in India have conducted a study showing that the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – was lower among people living with HIV and AIDS than among the general population.

23 Jun 2021

Tips of cancer survivors' tongues are less sensitive to tastes, study finds

Most survivors of squamous cell head and neck cancers report that their sense of taste is dulled, changed or lost during radiation treatment, causing them to lose interest in eating and diminishing their quality of life.

23 Jun 2021

Western high-fat diet can increase the risk of chronic pain

A typical Western high-fat diet can increase the risk of painful disorders common in people with conditions such as diabetes or obesity, according to a groundbreaking paper authored by a team led by The University of Texas Health Science Center at San Antonio, also referred to as UT Health San Antonio.

23 Jun 2021

More older adults may have undiagnosed dementia than previously estimated

Only 1 in 10 older adults in a large national survey who were found to have cognitive impairment consistent with dementia reported a formal medical diagnosis of the condition.

23 Jun 2021

Flavoring can change how the brain responds to nicotine e-cigarettes

Flavoring can change how the brain responds to e-cigarette aerosols that contain nicotine, according to Penn State College of Medicine researchers.

23 Jun 2021

NIH begins study to evaluate how pregnant, postpartum people react to COVID-19 vaccines

A new observational study has begun to evaluate the immune responses generated by COVID-19 vaccines administered to pregnant or postpartum people.

23 Jun 2021

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

A new study published on the bioRxiv* server describes the changes in the representation of a subset of activated monocytes in this group of patients.

23 Jun 2021

Researchers study COVID-19 immune dysfunction in relation to phosphatidylserine

Often patients suffering from COVID-19 (coronavirus disease) show striking immune dysregulation - causing increased morbidity and mortality. Mechanisms for adaptive immune disturbance, lymphopenia, and thromboinflammation in COVID-19 are still poorly understood.

23 Jun 2021

Exploring young people’s perspectives on patient-reported outcome measures in inflammatory arthritis

Inflammatory arthritis is the name for a group of diseases that cause joint pain and swelling. This happens because the body's immune system attacks its own tissues and causes inflammation.

23 Jun 2021

Study focuses on retinal roughness in Alzheimer’s disease

Over recent years, the retina has established its position as one of the most promising biomarkers for the early diagnosis of Alzheimer's.

23 Jun 2021

Medical Research News

Resurgent SARS-CoV-2 infections in England linked to Delta variant

Internal communication network in mammals provides new insights on obesity, skin disorders

Machine-learning approach could accurately predict the evolution of breast cancer

New class of compounds can stop the reproduction of coronavirus

Biomarker of chronic cellular stress is associated with Huntington's disease, shows study

A study of circulating biomarkers in hospitalized patients infected with SARS-CoV-2 alpha variant

SARS-CoV-2 detection with a simple, inexpensive, and sensitive molecular test

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

SARS-CoV-2 Delta variant likely to become dominant in the United States

New antibody conjugate delivers drugs to bone tumors and inhibits metastasis

Research suggests people living with HIV/AIDS may be less susceptible to SARS-CoV-2

Tips of cancer survivors' tongues are less sensitive to tastes, study finds

Western high-fat diet can increase the risk of chronic pain

More older adults may have undiagnosed dementia than previously estimated

Flavoring can change how the brain responds to nicotine e-cigarettes

NIH begins study to evaluate how pregnant, postpartum people react to COVID-19 vaccines

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

Researchers study COVID-19 immune dysfunction in relation to phosphatidylserine

Exploring young people’s perspectives on patient-reported outcome measures in inflammatory arthritis

Study focuses on retinal roughness in Alzheimer’s disease

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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