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Immune tolerance in hemophilia can be modulated by B cell activating factor

A group of scientists have just made a key discovery that could prevent and eradicate immune responses that lead to treatment failure in about one-third of people with severe hemophilia A.

20 Apr 2021

K162 molecule could inhibit β-amyloids ' toxicity associated with Alzheimer's disease

Alzheimer's disease (AD) is a form of progressive dementia interfering with daily living. It is caused by the decline in the number of brain cells resulting in the deterioration of our mental abilities.

20 Apr 2021

Study offers new insights on sleep apnea surgery, postoperative respiratory depression

An estimated 50 million people undergo surgery each year in the United States, and a significant proportion of them have undiagnosed or untreated sleep disorders (SD) or sleep-disordered breathing (SDB).

20 Apr 2021

POT1 gene linked to glioma development mediates its effects in a sex-specific manner

Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner.

20 Apr 2021

Use of ozone as a decontaminant for SARS-CoV-2

Researchers in Germany have demonstrated how an ozone-based decontamination device significantly reduces the volume of viral residue left on surfaces of two surrogate viruses for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

20 Apr 2021

Screening drug candidates for COVID-19 treatment using computational methods

Researchers identified two potential drug candidates that can inhibit SARS-CoV-2 in vitro. Their combination can work synergistically and increase their inhibitory effect.

19 Apr 2021

Sinovac COVID-19 vaccine shows 50% effectiveness in a cohort of Brazilian healthcare workers

CoronaVac is a well-tolerated vaccine containing inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and it induced humoral responses in phase 1 and 2 studies. Analysis of a Brazilian phase 3 clinical trial that evaluated 12,607 participants showed that the vaccine had an efficacy of 50.39% 15 days after the 2nd dose.

19 Apr 2021

Integrating social determinants of health in blood pressure management can improve patient outcomes

While cardiovascular disease (CVD) remains the leading cause of death globally, new research led by NYU Grossman School of Medicine and Moi University School of Medicine (Kenya) found that addressing and incorporating social determinants of health (such as poverty and social isolation) in the clinical management of blood pressure in Kenya can improve outcomes for patients with diabetes or hypertension.

19 Apr 2021

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

In a study by Yale Cancer Center, researchers report on the discovery of a common mechanism that promotes both autoimmune diseases and blood cancers, including the blood diseases Acute Lymphoblastic Leukemia (ALL), Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL).

19 Apr 2021

Study uncovers role for STING in regulating tumor response to DNA-damaging treatments

In a study by Yale Cancer Center, researchers report on the discovery of a new role for STimulator of INterferon Genes or STING.

19 Apr 2021

Study shows adverse outcomes associated with use of more blood thinners

More blood thinners aren't automatically better, another study confirms. A new publication in JAMA Internal Medicine focuses on the minimal pros and the concerning cons of combining a daily aspirin with a drug from the newer class of anticoagulants that include apixaban, dabigatran, edoxaban and rivaroxaban.

19 Apr 2021

Researchers reveal the effect of ultra-processed foods on skeleton development

A team of researchers from the Hebrew University of Jerusalem has proven the linkages between ultra-processed foods and reduced bone quality, unveiling the damage of these foods particularly for younger children in their developing years.

19 Apr 2021

Study identifies COVID-19 vaccine inequity in Massachusetts

A new study led by Bisola O. Ojikutu of Brigham and Women’s Hospital in Boston suggests not only do these communities have a higher infection, but they are also experiencing lower vaccine distribution. The team suggests that reformation for equitable vaccine delivery is necessary to eliminate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Apr 2021

COVID-19 patients who are overweight or obese may develop a more severe infection

COVID-19 patients who are overweight or obese are more likely to develop a more severe infection than patients of healthy weight, and they require oxygen and invasive mechanical ventilation more often. There is no increased risk of death .

19 Apr 2021

Just one mRNA vaccine dose sufficient for people with prior SARS-CoV-2 infection

A small study, previously posted to the medRiv preprint server in early March, was recently published in the journal Science Immunology. The now peer-reviewed research led by E. John Wherry of the University of Pennsylvania Perelman School of Medicine finds people previously exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produced a more robust immune response after receiving the first — but not the second mRNA vaccine.

19 Apr 2021

Majority of Americans support COVID-19 vaccine mandates, study finds

As vaccines that help protect against COVID-19 become available for more people across the United States, questions have been raised about whether institutions like schools and universities should require their students and staff to become vaccinated.

19 Apr 2021

Chemical biomarker could be used to better manage treatments for COVID-19

Varying severity of COVID-19 symptoms in patients is reflected by levels of a chemical biomarker in their body which scientists say could be used to better manage treatments and other interventions, including vaccinations.

19 Apr 2021

Researchers test whether feces transplantation can help patients with cirrhosis of the liver

Researchers from Aarhus University and Aarhus University Hospital replace sick intestinal bacteria with intestinal bacteria from healthy donors in a treatment intended to help patients with cirrhosis of the liver. The Novo Nordisk Foundation supports the project with just over DKK 13 million.

19 Apr 2021

Researchers show how to evaluate waning efficacy of COVID-19 vaccines

Researchers in the United States have demonstrated how to estimate the potentially waning efficacy of vaccines designed to protect against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

19 Apr 2021

Topical drug regenerates, restores function of erectile nerves damaged by radical prostatectomy

Researchers at Albert Einstein College of Medicine have developed a topical drug that regenerates and restores the function of erectile nerves damaged by radical prostatectomy, the most common treatment for localized prostate cancer.

19 Apr 2021

Medical Research News

Immune tolerance in hemophilia can be modulated by B cell activating factor

K162 molecule could inhibit β-amyloids ' toxicity associated with Alzheimer's disease

Study offers new insights on sleep apnea surgery, postoperative respiratory depression

POT1 gene linked to glioma development mediates its effects in a sex-specific manner

Use of ozone as a decontaminant for SARS-CoV-2

Screening drug candidates for COVID-19 treatment using computational methods

Sinovac COVID-19 vaccine shows 50% effectiveness in a cohort of Brazilian healthcare workers

Integrating social determinants of health in blood pressure management can improve patient outcomes

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

Study uncovers role for STING in regulating tumor response to DNA-damaging treatments

Study shows adverse outcomes associated with use of more blood thinners

Researchers reveal the effect of ultra-processed foods on skeleton development

Study identifies COVID-19 vaccine inequity in Massachusetts

COVID-19 patients who are overweight or obese may develop a more severe infection

Just one mRNA vaccine dose sufficient for people with prior SARS-CoV-2 infection

Majority of Americans support COVID-19 vaccine mandates, study finds

Chemical biomarker could be used to better manage treatments for COVID-19

Researchers test whether feces transplantation can help patients with cirrhosis of the liver

Researchers show how to evaluate waning efficacy of COVID-19 vaccines

Topical drug regenerates, restores function of erectile nerves damaged by radical prostatectomy

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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