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Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

Study identifies how SARS-CoV-2 enters and infects the brain

A recent preclinical study led by Anja Kipar of the University of Zurich and the University of Liverpool found evidence of the virus infecting and eventually provoking cell death in microglia and immune cells — but not neurons. The viral-induced apoptosis in these brain cells may explain why some long-haulers experience ‘brain fog’ months after recovery.

21 Apr 2021

Inhibition of Meprin Β enzyme can trigger the development of Alzheimer's disease, cancer

Researchers at Johannes Gutenberg University Mainz (JGU) in Germany and the Institute of Molecular Biology of Barcelona in Spain have discovered how the blood plasma protein fetuin-B binds to the enzyme meprin β and used a computer model to visualize their findings.

21 Apr 2021

Fast oscillations in electroencephalography can pinpoint brain tissues responsible for epileptic seizures

Professor Bin He's team at Carnegie Mellon University, in collaboration with the Mayo Clinic, has discovered that fast oscillations in scalp-recorded electroencephalography can pinpoint brain tissues responsible for epileptic seizures.

21 Apr 2021

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation--at least when all is functioning normally.

21 Apr 2021

SARS-CoV-2-associated ssRNAs trigger inflammation and immunity via toll-like receptors

Severe COVID-19 causes sepsis-like manifestations, intense lung injury, and multi-organ failure, all associated with the overproduction of pro-inflammatory cytokines. This "cytokine storm" directly correlates with poor prognosis in this subgroup of patients.

21 Apr 2021

Seroprevalence studies monitoring SARS-CoV-2 among vaccinees require more than spike assays

Researchers in the United States have shown that an antibody test measuring host reactivity to the nucleocapsid protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may better detect natural infection among vaccinated individuals than an assay that measures reactivity to the viral spike protein.

21 Apr 2021

Children develop strong, long-lasting immunity following SARS-CoV-2 infection

Researchers in the UK have conducted a study that may explain why children who become infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) do not generally develop severe coronavirus disease 2019 (COVID-19).

20 Apr 2021

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain - an early step in the development of Alzheimer's disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests.

20 Apr 2021

Study explores how lessons from past crises could improve the pandemic response

The lack of accountability, poor communication and insufficient planning plaguing the government’s response to the COVID-19 pandemic -- especially in its early months -- have roots in how the nation responded to 9/11, Hurricane Katrina and the H1N1 swine flu, a new study involving the University of Washington found.

20 Apr 2021

Two extremes of female sexual behavior may be controlled by the same brain region

In many species, including humans and mice, the fluctuating levels of the hormones progesterone and estrogen determine whether the female is fertile or not. And in the case of mice, whether she's sexually receptive or not.

20 Apr 2021

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Just as e-cigarette ingredients can vary from one region to another, the health effects of vaping can have regional characteristics as well. A new study out of West Virginia University suggests that rural e-cigarette users are older--and often get sicker--than their urban counterparts.

20 Apr 2021

Researchers reveal a potential therapeutic strategy against T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia in which too many T-cell lymphoblasts, or immature white blood cells, are found in the bone marrow and blood.

20 Apr 2021

Racial and ethnic diversity in schools influence student mental health, study finds

A Texas A&M researcher is discovering the demographic characteristics that can produce or lessen stress for racial and ethnic minority students in school settings.

20 Apr 2021

Study identifies higher mortality risk for women with back pain

New research from Boston Medical Center identifies elevated mortality risk for women with back pain when compared to women without back pain. Back pain was not associated with mortality among men indicating long-term consequences of back pain may differ by sex.

20 Apr 2021

Physical and mental health decline associated with more pronounced cognitive disengagement

A recent study suggests that preserving physical and mental health helps older adults experiencing cognitive impairment stave off declines in cognitive engagement.

20 Apr 2021

Personal and work-related factors can increase risk for neck pain

With roughly 80% of jobs being sedentary, often requiring several hours of sitting stooped in front of a computer screen, neck pain is a growing occupational hazard. Smartphones and other devices have also caused people to bend their necks for prolonged periods. But is bad posture solely to blame?

20 Apr 2021

Medical Research News

Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

Study identifies how SARS-CoV-2 enters and infects the brain

Inhibition of Meprin Β enzyme can trigger the development of Alzheimer's disease, cancer

Fast oscillations in electroencephalography can pinpoint brain tissues responsible for epileptic seizures

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

SARS-CoV-2-associated ssRNAs trigger inflammation and immunity via toll-like receptors

Seroprevalence studies monitoring SARS-CoV-2 among vaccinees require more than spike assays

Children develop strong, long-lasting immunity following SARS-CoV-2 infection

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

Study explores how lessons from past crises could improve the pandemic response

Two extremes of female sexual behavior may be controlled by the same brain region

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Researchers reveal a potential therapeutic strategy against T-cell acute lymphoblastic leukemia

Racial and ethnic diversity in schools influence student mental health, study finds

Study identifies higher mortality risk for women with back pain

Physical and mental health decline associated with more pronounced cognitive disengagement

Personal and work-related factors can increase risk for neck pain

Targeted therapy may be of great benefit in early stage breast cancer

MIND Institute study of anxiety in children with ASD has now expanded to offer online treatment

Researchers develop new biomaterial that regrows blood vessels and bone

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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