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Can SARS-CoV-2 host factor protein interactions help identify antiviral drug targets?

In a new study proteomic peptide-phage display is utilized to profile the novel SLiM-based interactions that mediate host factor interactions in 229 RNA viruses, with a special focus on SARS-CoV-2, to reveal mechanistic insights and identify drug targets.

22 Apr 2021

Pregnant and postpartum women at elevated risk of mental health problems during COVID-19 pandemic

Substantial proportions of pregnant and postpartum women scored high for symptoms of anxiety, depression, loneliness and post-traumatic stress in relation to COVID-19 in a survey carried out in May and June 2020, according to a new study published this week in the open-access journal PLOS ONE by Karestan Koenen and Archana Basu of Harvard T.H. Chan School of Public Health, US, and colleagues.

22 Apr 2021

Mental health disorders increased sharply among Americans during first 9 months of COVID-19 pandemic

Confirming anecdotal evidence that the spread of the coronavirus has strained Americans' mental health, Boston College researchers found reports of anxiety increased to 50 percent and depression to 44 percent by November, 2020 - rates six times higher than 2019 - according to a new report in the journal Translational Behavioral Medicine.

22 Apr 2021

UTHSC researchers receive $1.99 million to advance understanding of diabetes pathophysiology

The National Institute of Diabetes and Digestive and Kidney Diseases recently awarded a team of UTHSC researchers $1.99 million for their work to advance understanding of the pathophysiology of prediabetes, diabetes, and related complications.

22 Apr 2021

How effective is the Pfizer-BioNTech (BNT162b2) COVID-19 vaccine? A real-world study in Sweden

Investigating a population in southern Sweden, a new study has found that a single dose of the vaccine is only about 42% effective in preventing coronavirus disease 2019 (COVID-19). But seven days after the second dose, the vaccine can prevent COVID-19 in 86% of the population.

22 Apr 2021

Low iodine levels in women increase risk of impaired fetal intellectual development in pregnancy

An increasing number of young Australian women are at increased risk of having children born with impaired neurological conditions, due to poor iodine intake.

22 Apr 2021

Researchers conduct a SARS-CoV-2 serosurvey of blood donors in New Zealand

New research has been released, which focuses on the transmission and prevalence of SARS-CoV-2 in New Zealand, through a blood donor serosurvey.

22 Apr 2021

Researchers aim to better understand clinical features associated with COVID-19 mortality

To better understand the COVID-19 clinical feaures associated with mortality, an interdisciplinary team of researchers has investigated important factors and their influence on a patient’s death.

22 Apr 2021

World Malaria Day 2021: Finding new approaches to fight malaria

In observation of World Malaria Day, News-Medical interviews renowned malaria expert Professor Maureen Coetzee about the fight against malaria.

22 Apr 2021

Study provides mechanistic insight into effects of regular coffee drinking on the brain’s network

A new study published in Molecular Psychiatry and sponsored by the Institute for Scientific Information on Coffee (ISIC), provides unique insights into the functional and connectivity changes that happen within the brain of regular coffee drinkers.

22 Apr 2021

Impact of proposed law would increase regulatory oversight of certain diagnostic tests

Legislation currently under consideration in the U.S. Congress would increase regulatory oversight of certain diagnostic tests, and a new study by researchers at Massachusetts General Hospital (MGH) and colleagues from several other institutions demonstrates that its potential impact will depend on key details in the bill's final language.

22 Apr 2021

New photoreceptors from human pluripotent stem cells restores sight to injured retinas

Tens of millions of people worldwide are affected by diseases like macular degeneration or have had accidents that permanently damage the light-sensitive photoreceptors within their retinas that enable vision.

22 Apr 2021

New research unravels how the brain encodes social network structure

The brain encodes information about our relationships and the relationships between our friends using areas involved in spatial processing, according to new research published in JNeurosci.

22 Apr 2021

Researchers examine if a naturally occurring protein can be used to prevent sight loss from glaucoma

Researchers funded by Fight for Sight, in partnership with The Spectacle Makers’ Charity and Glaucoma UK, are investigating if a naturally occuring protein in the body can be used to prevent sight loss from glaucoma.

22 Apr 2021

Study offers insights into protective effects of dietary supplements against COVID-19

Taking multivitamins, omega-3, probiotics or vitamin D supplements may lessen the risk of testing positive for SARS-CoV-2, the virus responsible for COVID-19 infection--at least among women--indicates a large population study, published online in the journal BMJ Nutrition Prevention & Health.

22 Apr 2021

Study casts doubt on promotion of 'Heat not Burn' products as less harmful alternative to cigarettes

The impact on lung cells of Heat not Burn products--a hybrid between traditional cigarettes and electronic vaping devices--may be no less harmful than that of conventional cigarettes, suggest the findings of a small comparative study, published online in the journal Thorax.

22 Apr 2021

Study describes “cocktail party effect” in people with hearing loss

Plenty of people struggle to make sense of a multitude of converging voices in a crowded room. Commonly known as the "cocktail party effect," people with hearing loss find it's especially difficult to understand speech in a noisy environment.

22 Apr 2021

People with multiple sclerosis experience subtle language impairments, study shows

Kessler Foundation researchers showed that people with multiple sclerosis (MS) experience subtle language impairments that standard neuropsychological tests may incorrectly attribute to impaired executive functions.

22 Apr 2021

Study changes traditional views on atherosclerosis, offers new avenues for treatment

WHO Peter Libby, MD, cardiovascular medicine specialist at Brigham and Women's Hospital and the Mallinckrodt Professor of Medicine at Harvard Medical School; author of a new review paper published in Nature.

22 Apr 2021

Experts to present latest research on aging and longevity at the 8th Aging Research & Drug Discovery Meeting

Scheibye-Knudsen Lab, University of Copenhagen and Deep Longevity are excited to reveal the speakers for the 8th Aging Research & Drug Discovery Meeting, the largest scientific academic, and industry conference that will transpire on August 31 - September 3, 2021, on-site at the Ceremonial Hall, University of Copenhagen, and online.

22 Apr 2021

Medical Research News

Can SARS-CoV-2 host factor protein interactions help identify antiviral drug targets?

Pregnant and postpartum women at elevated risk of mental health problems during COVID-19 pandemic

Mental health disorders increased sharply among Americans during first 9 months of COVID-19 pandemic

UTHSC researchers receive $1.99 million to advance understanding of diabetes pathophysiology

How effective is the Pfizer-BioNTech (BNT162b2) COVID-19 vaccine? A real-world study in Sweden

Low iodine levels in women increase risk of impaired fetal intellectual development in pregnancy

Researchers conduct a SARS-CoV-2 serosurvey of blood donors in New Zealand

Researchers aim to better understand clinical features associated with COVID-19 mortality

World Malaria Day 2021: Finding new approaches to fight malaria

Study provides mechanistic insight into effects of regular coffee drinking on the brain’s network

Impact of proposed law would increase regulatory oversight of certain diagnostic tests

New photoreceptors from human pluripotent stem cells restores sight to injured retinas

New research unravels how the brain encodes social network structure

Researchers examine if a naturally occurring protein can be used to prevent sight loss from glaucoma

Study offers insights into protective effects of dietary supplements against COVID-19

Study casts doubt on promotion of 'Heat not Burn' products as less harmful alternative to cigarettes

Study describes “cocktail party effect” in people with hearing loss

People with multiple sclerosis experience subtle language impairments, study shows

Study changes traditional views on atherosclerosis, offers new avenues for treatment

Experts to present latest research on aging and longevity at the 8th Aging Research & Drug Discovery Meeting

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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