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S-2-hydroxyglutarate keeps endothelial cells in a dormant state, reveals study

The inner surface of blood vessels is lined by a wafer-thin layer of cells known as the endothelium, which forms a crucial barrier between blood and the surrounding tissue.

16 Apr 2021

Single dose of Oxford–AstraZeneca COVID vaccine shown to be more immunogenic than natural infection

By investigating antibody and T cell responses to a single dose of the Oxford–AstraZeneca COVID-19 vaccine, researchers from Sri Lanka and the United Kingdom have found that more than 90% of vaccinated individuals produced an adequate amount of antibodies after receiving only one dose of the vaccine – irrespective of their age and gender.

16 Apr 2021

Study evaluates the impact of alternative payment schedules to mitigate drug-related harms

A study published this week in The Lancet Public Health examines how we can use our income assistance systems to address drug use and drug-related harm.

16 Apr 2021

Study: Previous COVID-19 infection does not completely protect against reinfection in young people

A past COVID-19 infection does not completely protect against reinfection in young people, according to an observational study of more than 3,000 healthy members of the US Marines Corps most of whom were aged 18-20 years, published in The Lancet Respiratory Medicine journal.

16 Apr 2021

Remote and virtual health care models can negatively impact small physician offices

In a newly released study, researchers found that remote and virtual care models can negatively impact small physician offices.

16 Apr 2021

Epigenetic endowment of every person has an impact on COVID-19 severity

COVID-19, caused by the infection of the SARS-CoV-2 virus, has changed people's behavioral patterns since the moment it became a global pandemic.

15 Apr 2021

COVID-19 vaccine INO-4800 shows efficacy against SARS-CoV-2 variants

Researchers in the United States have demonstrated the efficacy of the vaccine INO-4800 against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

15 Apr 2021

Feline model of SARS-CoV-2 infection imitates COVID-19 in humans

Researchers in the United States have validated a feline model of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that closely imitates coronavirus disease 2019 (COVID-19) in humans.

15 Apr 2021

An ion pump tested as a possible method to treat malignant brain tumors

Despite surgery and subsequent treatment with chemotherapy and radiation, the majority of patients experience recurrence of malignant brain tumors.

15 Apr 2021

Obese or overweight patients at high risk for having worse COVID-19 outcomes

Patients who are overweight or obese have more severe COVID-19 and are highly likely to require invasive respiratory support, according to a new international study.

15 Apr 2021

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

Osteoarthritis affects the joints, but according to researcher Michael Zuscik, PhD, it may start in the gut.

15 Apr 2021

Researchers develop a classification scheme for neuromyelitis optica spectrum disorder

Researchers in the Department of Neurology at Tohoku University, which is led by professor Masashi Aoki, have developed a classification scheme for neuromyelitis optica spectrum disorder, a rare autoimmune disease that until recently was thought to be a type of multiple sclerosis (MS).

15 Apr 2021

Researchers identify two distinct phenotypes of COVID-19-associated ARDS

Approximately one in four patients hospitalized for the acute respiratory distress syndrome (ARDS) associated with severe COVID-19 infections may have a distinct phenotype (disease presentation) or biochemical profile associated with organ dysfunction, blood-clotting abnormalities and greater risk of death than patients with other, seemingly similar forms of the disease, researchers at Massachusetts General Hospital have found.

15 Apr 2021

Japanese–European scientists detect novel genetic mitochondrial disorder

The list of known genetic mitochondrial disorders is ever-growing, and ongoing research continues to identify new disorders in this category.

15 Apr 2021

Personality trait neuroticism associated with higher risk of Parkinson's disease

New research from the Florida State University College of Medicine has found that the personality trait neuroticism is consistently associated with a higher risk of developing the brain disorder Parkinson's disease.

15 Apr 2021

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis.

15 Apr 2021

CHOP researchers identify key target responsible for treatment failure in patients with hemophilia A

Researchers at Children's Hospital of Philadelphia have identified a key target that may be responsible for treatment failure in about 30% of patients with hemophilia A.

15 Apr 2021

Researchers develop “Nano-Glue” with therapeutic potential against SARS-CoV-2

In a recent study, researchers target the electropositive receptor-binding domain (RBD) on the SARS-CoV-2 spike protein with the abundant β-sheet structure as a novel COVID-19 therapeutic drug design.

15 Apr 2021

Keele researcher awarded prestigious grant to identify treatments for devastating childhood disease

A Keele researcher will embark on a two-year study to identify affordable treatments to help children living with spinal muscular atrophy.

15 Apr 2021

Researchers assess SARS-CoV-2 transmission risk during air travel

A team of scientists from the United States has recently conducted a meta-analysis to estimate the risk of SARS-CoV-2 infection during air travel. The findings reveal that even with SARS-CoV-2-infected persons onboard, the risk of viral transmission is low inside an aircraft.

15 Apr 2021

Medical Research News

S-2-hydroxyglutarate keeps endothelial cells in a dormant state, reveals study

Single dose of Oxford–AstraZeneca COVID vaccine shown to be more immunogenic than natural infection

Study evaluates the impact of alternative payment schedules to mitigate drug-related harms

Study: Previous COVID-19 infection does not completely protect against reinfection in young people

Remote and virtual health care models can negatively impact small physician offices

Epigenetic endowment of every person has an impact on COVID-19 severity

COVID-19 vaccine INO-4800 shows efficacy against SARS-CoV-2 variants

Feline model of SARS-CoV-2 infection imitates COVID-19 in humans

An ion pump tested as a possible method to treat malignant brain tumors

Obese or overweight patients at high risk for having worse COVID-19 outcomes

CU researcher receives NIH grant to analyze the link between gut microbiome and osteoarthritis

Researchers develop a classification scheme for neuromyelitis optica spectrum disorder

Researchers identify two distinct phenotypes of COVID-19-associated ARDS

Japanese–European scientists detect novel genetic mitochondrial disorder

Personality trait neuroticism associated with higher risk of Parkinson's disease

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

CHOP researchers identify key target responsible for treatment failure in patients with hemophilia A

Researchers develop “Nano-Glue” with therapeutic potential against SARS-CoV-2

Keele researcher awarded prestigious grant to identify treatments for devastating childhood disease

Researchers assess SARS-CoV-2 transmission risk during air travel

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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