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Inhibiting necroptosis could be a novel approach for treating COPD

Research shows that inhibiting necroptosis, a form of cell death, could be a novel therapeutic approach for treating chronic obstructive pulmonary disease, an inflammatory lung condition, also known as emphysema, that makes it difficult to breathe.

17 Jun 2021

Burden of asymptomatic pertussis in infants is greater than previously thought

New study challenges long-standing assumptions about disease severity in infants, and suggests that standard qPCR interpretations underestimate the true burden of other highly contagious diseases, such as COVID-19 and influenza.

17 Jun 2021

Improved treatment and better prognosis for testicular cancer patients

Testicular cancer is the most common cancer among men under 40 in Europe and the USA. National statistics from the Cancer League indicate 471 new cases and 12 deaths in Switzerland.

17 Jun 2021

RUDN University doctors find alterations in serum amino acid profile in children with ADHD

RUDN University doctors found alterations in serum amino acid profile in children with attention deficit hyperactivity disorder (ADHD).

17 Jun 2021

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

17 Jun 2021

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

The normal function of uromodulin, a protein that is made in the kidney and secreted into the urine, remains largely unknown. However, higher levels of uromodulin in the urine are related to lower rates of urinary tract infections and kidney stones, while higher levels of this protein in kidney cells are associated with higher rates of hypertension and chronic kidney disease.

17 Jun 2021

Neighborhood disadvantage related to increased COVID-19 infections and mortality

New York City neighborhoods that had higher levels of socioeconomic disadvantage experienced more COVID-19 infections and deaths, according to Mount Sinai scientists who created a neighborhood-level COVID-19 inequity index.

17 Jun 2021

How stable are mRNA vaccines under continuous movement?

Researchers tested reconstituted COVID-19 mRNA vaccines under different movement conditions and found that a moderate continuous movement does not damage the mRNA, which may increase the possibility of transporting reconstituted vaccine over a few hundred kilometers.

17 Jun 2021

Novel ferritin nanoparticle vaccine candidate effective against SARS-CoV-2 variants in preclinical trials

A team of scientists from the United States has recently evaluated the efficacy of a ferritin nanoparticle-formulated, SARS-CoV-2 spike-based vaccine against newly emerged Variants of Concern (VOCs).

17 Jun 2021

Could type III interferons be used as a SARS-CoV-2 therapeutic?

Researchers have found that both type I and type III interferons can inhibit SARS-CoV-2 infection in human intestinal cells, but type III interferons can act faster and for a longer period, making them suitable for potential therapeutics.

17 Jun 2021

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

In a new study, released as a preprint on the medRxiv* server, researchers from Germany, Italy and Netherlands demonstrated the utility of integrating genomic and wastewater based epidemiology (WBE) to provide unprecedented insight into the abundance of SARS-CoV-2 and the profile of the mutations associated with the VOCs (i.e., B.1.1.7, B.1.351, P.1, and B.1.617.2) in the wastewater samples.

17 Jun 2021

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

A new preprint recently released on the bioRxiv* server describes the immunogenicity and protective potential of a novel adenovirus SARS-CoV-2 vaccine candidate against a form of the virus adapted to cause severe disease in mice. The findings show that this provides a useful mouse model for the study of new vaccines, in addition to demonstrating the protective efficacy of the current rhesus adenovirus vaccine candidate RhAd52.

17 Jun 2021

What impacts public compliance with COVID-19 restrictions?

New research by scientists at Switzerland's Institute for Environmental Decisions reports that risk perception and public acceptance of NPIs depends on both worldview and levels of social trust. The study also found that, paradoxically, when the number of cases decreased in the period between the first and second waves, public willingness to comply with these measures fell.

17 Jun 2021

How the common cold can provide protection against COVID-19

In a recent study, researchers found that prior infection with the rhinovirus can provide a more effective immune response against SARS-CoV-2 infection.

17 Jun 2021

High junk food consumption in childhood increases risk of unhealthy body fat by early adulthood

A new paper published recently in the journal JAMA Pediatrics reports consistent and significant associations between the increased consumption of such ‘ultraprocessed foods’ by children in the UK, and a higher risk of obesity, increased body fat percentage, and overall body mass, by the time they reach young adulthood.

17 Jun 2021

A 'key clinical role' for community pharmacies in COVID-19 vaccination campaigns

Community pharmacies represent credible services across the UK, which could be key to COVID-19 vaccination campaigns.

17 Jun 2021

Marine plastic pollution among the top marine-related threats of public concern

In a survey, researchers found that the impacts of marine plastic pollution on human health is now ranked amid the top health-related concerns.

17 Jun 2021

Landmark multiple myeloma study completes enrolment and method development

Binding Site is pleased to announce that the ground-breaking iStopMM study has reached an important milestone.

From Binding Site 17 Jun 2021

New noninvasive biomarker can be used in the diagnosis of NAFLD

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and can progress to liver cirrhosis, liver failure or cancer. Currently, nonalcoholic steatohepatitis (NASH) diagnosis requires an invasive liver biopsy which can lead to procedural complications.

17 Jun 2021

MicroRNAs in urine could be a promising biomarker to diagnose brain tumors, study reveals

A recent study by Nagoya University researchers revealed that microRNAs in urine could be a promising biomarker to diagnose brain tumors.

17 Jun 2021

Medical Research News

Inhibiting necroptosis could be a novel approach for treating COPD

Burden of asymptomatic pertussis in infants is greater than previously thought

Improved treatment and better prognosis for testicular cancer patients

RUDN University doctors find alterations in serum amino acid profile in children with ADHD

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

Neighborhood disadvantage related to increased COVID-19 infections and mortality

How stable are mRNA vaccines under continuous movement?

Novel ferritin nanoparticle vaccine candidate effective against SARS-CoV-2 variants in preclinical trials

Could type III interferons be used as a SARS-CoV-2 therapeutic?

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

What impacts public compliance with COVID-19 restrictions?

How the common cold can provide protection against COVID-19

High junk food consumption in childhood increases risk of unhealthy body fat by early adulthood

A 'key clinical role' for community pharmacies in COVID-19 vaccination campaigns

Marine plastic pollution among the top marine-related threats of public concern

Landmark multiple myeloma study completes enrolment and method development

New noninvasive biomarker can be used in the diagnosis of NAFLD

MicroRNAs in urine could be a promising biomarker to diagnose brain tumors, study reveals

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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