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Previously approved drugs starting points for COVID-19 therapeutics

Researchers in the United States have identified several clinically approved compounds that could be repurposed for the treatment and prevention of coronavirus disease 2019 (COVID-19).

11 Apr 2021

New polypeptide could provide universal protection against coronaviruses

Researchers in the United States have developed an inhibitor of the spike protein found on the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that limits its formation in host human cells that would otherwise be the source of newly generated virions.

11 Apr 2021

Job and social strain associated with higher risk of coronary heart disease in women

Psychosocial stress - typically resulting from difficulty coping with challenging environments - may work synergistically to put women at significantly higher risk of developing coronary heart disease, according to a study by researchers at Drexel University's Dornsife School of Public Health, recently published in the Journal of the American Heart Association.

9 Apr 2021

Broadly neutralizing antibodies show promise in preventing tick-borne encephalitis in mice

Tick-borne encephalitis is a disease just as nasty as it sounds. Once bitten by an infected tick, some people develop flu-like symptoms that resolve quietly but leave behind rampant neurological disease--brain swelling, memory loss, and cognitive decline.

9 Apr 2021

Sleep apnea treatment linked to lower risk of Alzheimer's and other dementias

A new study finds older adults who received positive airway pressure therapy prescribed for obstructive sleep apnea may be less likely to develop Alzheimer's disease and other kinds of dementia.

9 Apr 2021

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Experts have uncovered a new molecular reason why faecal transplants are highly effective in treating infections such as C. difficile (a nasty bacteria that can infect the bowel), which could lead to more targeted treatments for this and other similar diseases.

9 Apr 2021

Analysis highlights the need for a more nuanced approach to COVID-19 vaccine prioritization

It's time for a more nuanced approach to vaccine prioritization, as more contagious COVID-19 variants become prevalent and a third wave of infections threatens to overwhelm hospitals in some provinces, according to an analysis published today in the Canadian Medical Association Journal.

9 Apr 2021

New biosealant therapy may help treat damaged cartilage tissue

A new biosealant therapy may help to stabilize injuries that cause cartilage to break down, paving the way for a future fix or - even better - begin working right away with new cells to enhance healing, according to a new animal-based study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

9 Apr 2021

Canada should take a more nuanced approach when setting SARS-CoV-2 vaccine priorities

When setting SARS-CoV-2 vaccine priorities, Canada should take a more nuanced approach that considers geographic and occupational risk exposures, as 75% of Canadian adults have at least 1 risk factor for severe COVID-19, argues an analysis in CMAJ.

9 Apr 2021

Advanced computer model could lead to improvements in 'bionic eye' technology

There are millions of people who face the loss of their eyesight from degenerative eye diseases. The genetic disorder retinitis pigmentosa alone affects 1 in 4,000 people worldwide.

9 Apr 2021

Children may be less infectious in spreading SARS-CoV-2 to others

Children may not be as infectious in spreading SARS-CoV-2 to others as previously thought, according to new University of Manitoba-led research in CMAJ.

9 Apr 2021

CARA bill to increase nurse practitioner’s buprenorphine prescribing falls short

Since 2016, a federal regulation has allowed nurse practitioners and physician assistants to obtain a waiver to prescribe buprenorphine, a medication used to treat opioid use disorder as a medication assisted treatment.

9 Apr 2021

SA’s 2018 'sugar tax' has led to reduction in purchases of sugar sweetened beverages, study shows

A study by PRICELESS-SA and partners shows that SA’s 2018 “sugar tax” led to a reduction in purchases of sugar sweetened beverages (SSBs).

9 Apr 2021

Hay fever and asthma occur earlier in life and affect more people

The unpopular guests are already here. Hazel-, alder- and elm tree pollen sweep in over us during the early spring months, with birch pollen following in May. Then grass follows in June-July before mugwort pollen closes the season in late summer. All leading to more and more people suffering.

9 Apr 2021

Study shows intricate association of aluminum in the neuropathology of familial Alzheimer's disease

This study builds upon two earlier published studies (Mold et al., 2020, Journal of Alzheimer's Disease Reports) from the same group. The new data, also published in the Journal of Alzheimer's Disease Reports, demonstrate that aluminum is co-located with phosphorylated tau protein, present as tangles within neurons in the brains of early-onset or familial Alzheimer's disease (AD).

9 Apr 2021

Frontline health workers experienced unprecedented levels of stress during the pandemic

During the acute phase of the COVID-19 pandemic, emergency department doctors, nurses and other frontline staff experienced unprecedented levels of stress and emotional exhaustion that included nightmares or insomnia, according to a UC San Francisco-led study of emergency departments across the country.

9 Apr 2021

Researchers identify several novel SARS-CoV-2 inhibitors

Researchers in London, UK, have identified several compounds with SARS-CoV-2 inhibiting properties, that potentially may be developed into antiviral solutions in the future.

9 Apr 2021

Researchers discover a new monoclonal antibody that is effective against SARS-CoV-2 variants

A new monoclonal antibody targets a particular region of the RBD on the SARS-CoV-2. This region is usually not accessible to immune cells, which may be why it has broad neutralizing capabilities.

9 Apr 2021

How has the COVID-19 pandemic affected sleep patterns for many US citizens?

A team of scientists recently conducted an online survey to examine the changes in sleep duration among adult US citizens during the COVID-19 pandemic.

9 Apr 2021

Antipsychotics could have a protective impact against SARS-CoV-2

Two studies led by the Mental Health Unit of the Virgen del Rocio University Hospital and involving researchers from the US conclude that antipsychotic drugs could have a protective effect against SARS-CoV-2. For this reason, patients treated with these drugs have a lower risk of becoming infected or suffer a milder form of the disease if they do become infected.

9 Apr 2021

Medical Research News

Previously approved drugs starting points for COVID-19 therapeutics

New polypeptide could provide universal protection against coronaviruses

Job and social strain associated with higher risk of coronary heart disease in women

Broadly neutralizing antibodies show promise in preventing tick-borne encephalitis in mice

Sleep apnea treatment linked to lower risk of Alzheimer's and other dementias

Study uncovers molecular reason why fecal transplants effectively treat C. difficile infections

Analysis highlights the need for a more nuanced approach to COVID-19 vaccine prioritization

New biosealant therapy may help treat damaged cartilage tissue

Canada should take a more nuanced approach when setting SARS-CoV-2 vaccine priorities

Advanced computer model could lead to improvements in 'bionic eye' technology

Children may be less infectious in spreading SARS-CoV-2 to others

CARA bill to increase nurse practitioner’s buprenorphine prescribing falls short

SA’s 2018 'sugar tax' has led to reduction in purchases of sugar sweetened beverages, study shows

Hay fever and asthma occur earlier in life and affect more people

Study shows intricate association of aluminum in the neuropathology of familial Alzheimer's disease

Frontline health workers experienced unprecedented levels of stress during the pandemic

Researchers identify several novel SARS-CoV-2 inhibitors

Researchers discover a new monoclonal antibody that is effective against SARS-CoV-2 variants

How has the COVID-19 pandemic affected sleep patterns for many US citizens?

Antipsychotics could have a protective impact against SARS-CoV-2

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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