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Protein in prostate cancer may prevent tumor from spreading to the bone

Prostate cancer is the second most common cancer among men, according to the American Cancer Society. It's also one of the trickiest cancers to diagnose and treat.

9 Jun 2021

DNA on-off switches for SARS-CoV-2 host receptor as potential therapeutic targets

Researchers in the United States and Canada have identified DNA on/off “switches” within the angiotensin-converting enzyme 2 (ACE2) gene that may control the expression of this host cell receptor before, during and after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Jun 2021

Cold winter temperatures may accelerate spread of SARS-CoV-2

Writing in the journal Frontiers in Public Health, the team from Weifang Medical University said: “We believe that the low-temperature environment in winter may accelerate the spread of the outbreak and that new outbreaks may occur.”

9 Jun 2021

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

A new bioRxiv preprint attempts to make some sense of why certain people experience more severe forms of COVID-19 as compared to others by pointing to the increase in virus binding that occurs in the presence of smoking or vaping.

9 Jun 2021

Poorly fitting face masks increase the risk of airborne diseases

Even the best face masks work only as well as their fit. And poorly fitting face masks greatly increase the risk of infection from airborne pathogens compared to custom-fitted masks, according to a new study by the University of Cincinnati.

9 Jun 2021

Clinical trial investigates effectiveness of delivering HIV, substance use care through mobile clinics

A clinical trial is underway in five U.S. cities to determine whether delivering integrated health services through mobile clinics can improve HIV and substance use outcomes among people with opioid use disorder who inject drugs.

9 Jun 2021

Researchers in Canada conduct a comparative study of household secondary attack rates connected with SARS-CoV-2 variants of concern

Scientists are considering a third surge in COVID-19 incidence owing to the emergence of highly transmissible SARS-CoV-2 variants of concern (VOC). SARS-CoV-2 is the causal agent of the current COVID-19 pandemic. Some of these VOCs have been reported to have a rate of transmission much higher than the infectivity of the ancestral strain that had emerged in Wuhan, China, in 2019.

9 Jun 2021

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

In a recently published article in the journal Frontiers in Immunology, scientists have reviewed the existing literature on antiviral and anti-inflammatory efficacy of resveratrol-based inhaled formulations in preventing SARS-CoV-2 infection and reducing COVID-19 severity.

9 Jun 2021

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

In a recent study published in the journal Pathogens, researchers carried out a molecular docking study for 17 structural analogs prepared from natural maslinic and oleanolic acids and screened them against SARS-CoV-2 main protease. They also experimentally validated the data by determining the half-maximal cytotoxic and inhibitory concentrations of each of the 17 compounds. The researchers investigated whether the compound with antiviral activity affected viral adsorption, replication, or viricidal effect using a plaque infectivity reduction assay.

9 Jun 2021

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

Researchers from the US used a systems immunology approach where they combined high-dimensional flow cytometry and multi-omics single-cell sequencing analyses of immune profiles taken from the airways and matching blood samples of Black/AA patients.

9 Jun 2021

What are the challenges of SARS-CoV-2 serosurveillance in COVID-19 vaccine recipients?

An opinion paper by researchers from the US and Italy recently discussed various aspects of monitoring anti-SARS-CoV-2 antibodies before and after receiving COVID-19 vaccination to highlight the pros and cons of this monitoring strategy. This paper is published in the open-access journal Diagnostics.

9 Jun 2021

Social media ‘bots’ continue to spread misinformation on mask wearing amid COVID-19 pandemic

While not a new problem, the spread of misinformation throughout the coronavirus disease 2019 (COVID-19) pandemic has exploded on almost every social media platform. Recently, a group of researchers analyzed conversations on public Facebook groups to explored automated misinformation on mask-wearing. The team published their findings as a research letter in the JAMA Internal Medicine journal.

9 Jun 2021

New poll suggests older adults must watch their alcohol intake during pandemic

As many older adults get back to normal life across the United States thanks to high rates of vaccination and lower COVID-19 activity, a new poll suggests many should watch their alcohol intake.

9 Jun 2021

A closer look at how COVID-19 damages human lungs

A recent study conducted at the United States Department of Energy’s (DOE) Brookhaven National Laboratory provides the first atomic-level detailed model of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope protein when bound to human proteins within the lungs. The study was recently published in Nature Communications.

9 Jun 2021

$Heavier birth weight is linked to higher risk of bone fracture later in life$

Heavier birth weight is linked to higher risk of bone fracture later in life

New research published in the Journal of Bone and Mineral Research has linked heavier birth weight with lower bone mineral density and a higher risk of bone fracture later in life.

9 Jun 2021

Study examines brain scans of COVID-19 patients

In a Journal of Neuroimaging analysis of data obtained from 193 patients with COVID-19 who had brain and/or spine imaging and a lumbar puncture because of neurologic symptoms, investigators found that imaging results were related to the presence of SARS-CoV-2 in the cerebrospinal fluid.

9 Jun 2021

New bacterium shows promise for treating type 2 diabetes, obesity

It all started, when Patrice Cani, FNRS researcher at University of Louvain (UCLouvain), and his team repeatedly observed that a bacterium (called Subdoligranulum) is almost absent in obese and diabetic people, while it is systematically present in healthy people. So, they decided to take a closer look at this "family" of bacteria.

9 Jun 2021

Medical Research News

Protein in prostate cancer may prevent tumor from spreading to the bone

DNA on-off switches for SARS-CoV-2 host receptor as potential therapeutic targets

Cold winter temperatures may accelerate spread of SARS-CoV-2

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

Poorly fitting face masks increase the risk of airborne diseases

Clinical trial investigates effectiveness of delivering HIV, substance use care through mobile clinics

Researchers in Canada conduct a comparative study of household secondary attack rates connected with SARS-CoV-2 variants of concern

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

Structural analogs of triterpenoids show strong inhibitory activity against coronaviruses

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

What are the challenges of SARS-CoV-2 serosurveillance in COVID-19 vaccine recipients?

Social media ‘bots’ continue to spread misinformation on mask wearing amid COVID-19 pandemic

New poll suggests older adults must watch their alcohol intake during pandemic

A closer look at how COVID-19 damages human lungs

Heavier birth weight is linked to higher risk of bone fracture later in life

Study examines brain scans of COVID-19 patients

New bacterium shows promise for treating type 2 diabetes, obesity

Mix and match COVID-19 vaccines safe and effective: German study

Youth with a history of foster care have less access to oral health care

Reconsidering the variations in children's speech

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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