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'Post-acute COVID-19 syndrome' likely to substantially impact NHS in England

Researchers in the UK have warned that cardiometabolic and pulmonary events among coronavirus disease 2019 (COVID-19) survivors following their discharge from hospital is likely to have an ongoing and substantial impact on the National Health Service (NHS) in England.

26 Jan 2021

£1.6 million grant awarded to advance development of MND drug candidate

Researchers from the University of Sheffield's Institute for Translational Neuroscience have been awarded a £1.6 million grant from the Medical Research Council.

26 Jan 2021

Autistic children may be more likely to misinterpret healthy arguments between their parents

A new study suggests children on the autism spectrum may be more likely to misinterpret healthy arguments between their parents as being negative, compared to children who aren't on the autism spectrum.

26 Jan 2021

Elevated levels of certain immune cells in the blood linked to COVID-19 severity

Individual variations in how the immune system responds to SARS-CoV-2 appear to impact the severity of disease.

26 Jan 2021

Moderna vaccine fully neutralizes new SARS-CoV-2 variants, study shows

Researchers in the United States have conducted a study showing that Moderna’s mRNA-1273 vaccine neutralizes all circulating variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tested to date.

26 Jan 2021

Neonatal antibiotic exposure linked to reduced weight and height in boys

Exposure to antibiotics in the first days of life is thought to affect various physiological aspects of neonatal development.

26 Jan 2021

New study to examine the role of extended family caregivers of people with dementia

Karen Roberto and Tina Savla, both core faculty members of Virginia Tech's Center for Gerontology, are leading a five-year, $2.14 million study that will examine the role of extended family caregivers and their service use, needs, and challenges.

26 Jan 2021

LSD could be a viable and safe therapeutic option for certain psychiatric diseases

Researchers from McGill University have discovered, for the first time, one of the possible mechanisms that contributes to the ability of lysergic acid diethylamide (LSD) to increase social interaction.

26 Jan 2021

New approach to mapping viral mutations that escape antibodies used to treat COVID-19

A new approach to mapping viral mutations that "escape" leading clinical antibodies has revealed mutations in the SARS-CoV-2 virus that allow it to evade treatments, including a single amino-acid mutation that fully escapes Regeneron's antibody cocktail.

26 Jan 2021

New discovery could lead to faster and more effective treatments for chronic health complications

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

26 Jan 2021

Prostate cancer: Drug-resistant, metastasis-causing cells can produce exponentially growing tumors

The cover for issue 1 of Oncotarget features Figure 2, "Results in clinical trials," published in "Drug resistant cells with very large proliferative potential grow exponentially in metastatic prostate cancer" by Blagoev, et al. which reported that most metastatic cancers develop drug resistance during treatment and continue to grow, driven by a subpopulation of cancer cells unresponsive to the therapy being administered.

26 Jan 2021

Machine learning identifies patterns of maternal autoantibodies associated with autism

Using machine learning, researchers at the UC Davis MIND Institute have identified several patterns of maternal autoantibodies highly associated with the diagnosis and severity of autism.

26 Jan 2021

Researchers develop method for presymptomatic COVID-19 detection

An encouraging new study by researchers at University College London, UK, reports the potential of a form of COVID-19 testing which can detect presymptomatic cases.

26 Jan 2021

Astrocytes might be a potential new target to better treat epilepsy

A significant number of epilepsy patients does not respond to currently available drugs. A collaboration between researchers in Japan and at the Heinrich Heine University Düsseldorf now addressed a cell type in the brain that has so far not received much attention in epilepsy therapy.

26 Jan 2021

Codon frequency optimization shows SARS-CoV-2 antiviral potential

A study conducted by researchers in the US has revealed that optimization of codon for bacterial expression causes the production of an inactive enzyme non-structural protein 12 (Nsp12), a catalytic subunit of RNA-dependent RNA polymerase of SARS-CoV-2.

26 Jan 2021

Researchers engineer antibody that broadly neutralizes a range of clade 1 sarbecoviruses

Researchers have engineered an antibody that neutralizes SARS-CoV-2 with a potency that "rivals" current lead SARS-CoV-2 clinical neutralizing antibodies, and that also broadly neutralizes a range of clade 1 sarbecoviruses.

26 Jan 2021

Five-day regimen of radiotherapy safe, effective for men with high-risk forms of prostate cancer

A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center found shortening a traditional 45-day course of radiation to a five-day course delivered in larger doses is safe and as effective as conventional radiation for men with high-risk forms of prostate cancer.

26 Jan 2021

Mutations in SARS-CoV-2 spike proteolytic cleavage sites may alter transmission dynamics

A study conducted by researchers at the University of Kentucky and the Washington University School of Medicine in the USA has revealed that mutations in the proteolytic cleavage site within the S2 subunit can alter the processing of the SARS-CoV-2 spike protein, affecting viral entry into host cells.

26 Jan 2021

Drug intervention may prevent heart damage caused by chemotherapy

There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests.

26 Jan 2021

Diabetes and glucose levels tied to increased risk of COVID-19 death

Researchers at Xijing Hospital, Fourth Military Medical University, Xi’an, China, found that diabetes and on-admission glucose levels may increase the risk of COVID-19 mortality.

26 Jan 2021

Medical Research News

'Post-acute COVID-19 syndrome' likely to substantially impact NHS in England

£1.6 million grant awarded to advance development of MND drug candidate

Autistic children may be more likely to misinterpret healthy arguments between their parents

Elevated levels of certain immune cells in the blood linked to COVID-19 severity

Moderna vaccine fully neutralizes new SARS-CoV-2 variants, study shows

Neonatal antibiotic exposure linked to reduced weight and height in boys

New study to examine the role of extended family caregivers of people with dementia

LSD could be a viable and safe therapeutic option for certain psychiatric diseases

New approach to mapping viral mutations that escape antibodies used to treat COVID-19

New discovery could lead to faster and more effective treatments for chronic health complications

Prostate cancer: Drug-resistant, metastasis-causing cells can produce exponentially growing tumors

Machine learning identifies patterns of maternal autoantibodies associated with autism

Researchers develop method for presymptomatic COVID-19 detection

Astrocytes might be a potential new target to better treat epilepsy

Codon frequency optimization shows SARS-CoV-2 antiviral potential

Researchers engineer antibody that broadly neutralizes a range of clade 1 sarbecoviruses

Five-day regimen of radiotherapy safe, effective for men with high-risk forms of prostate cancer

Mutations in SARS-CoV-2 spike proteolytic cleavage sites may alter transmission dynamics

Drug intervention may prevent heart damage caused by chemotherapy

Diabetes and glucose levels tied to increased risk of COVID-19 death

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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