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SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation

Researchers at the Erasmus Medical Centre in the Netherlands and the University of Illinois at Urbana-Champaign in the US found that SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation and that this can be prevented by using cell lines with an active serine protease-mediated entry pathway.

26 Jan 2021

Study shows several peridomestic mammal species are potential spreaders of SARS-CoV-2

Researchers from the US and Australia show that several common peridomestic species (including deer mice, striped skunks and bushy-tailed woodrats) are amenable to infection with SARS-CoV-2.

26 Jan 2021

New UK SARS-CoV-2 variant circulating in US since November, says study

A new study by researchers at the Department of Ecology and Evolutionary Biology, University of Arizona, showed that the new variant has circulated in the US since November.

26 Jan 2021

New SARS-CoV-2 variant must be curbed to protect UK health services, warn experts

A new research project called REACT-1 – launched by researchers at the Imperial College London, Imperial College Healthcare NHS Trust, and Ipsos MORI – has aimed to better understand the dynamics of SARS-CoV-2’s viral spread across the UK.

26 Jan 2021

Accelerating vaccine rollout may provide greatest reduction in COVID-19 mortality

A thought-provoking preprint research paper posted to the medRxiv server suggests that among several factors that could potentially contribute to the design of an optimal vaccine strategy aimed at the most significant possible reduction in COVID-19 mortality, timing is likely to be the most important factor.

26 Jan 2021

Recombinant SARS-CoV-2 protein vaccine less immunogenic but more antigenic than expected

Now, a new preprint research paper posted to the medRxiv server presents preliminary results of a stabilized SARS-CoV-2 pre-fusion spike protein vaccine expressed in a baculovirus system (CoV2 preS dTM), with two different adjuvant formulations.

26 Jan 2021

B.1.1.7 variant and healthcare workers’ travel worry

Recently a team of researchers from Saudi Arabia, the United Arab Emirates, and the United States assessed travel-related anxiety in healthcare workers (HCWs) considering the emergence of new variants caused by SARS-CoV-2 mutations.

25 Jan 2021

Research shows immediate phase of blood vessel restructuring after aneurysm

Hitting a pothole on the road in just the wrong way might create a bulge on the tire, a weakened spot that will almost certainly lead to an eventual flat tire. But what if that tire could immediately begin reknitting its rubber, reinforcing the bulge and preventing it from bursting?

25 Jan 2021

Optimistic pupils with 'happy' memories linked to lower drink and drug risk

Teenagers with happy childhood memories are likely to drink less, take fewer drugs and enjoy learning, according to research published in the peer-reviewed journal Addiction Research & Theory.

25 Jan 2021

Hyperinflammatory conditions drive gender differences in COVID-19 severity and mortality

Recently researchers from India analyzed gender differences in COVID-19-related hyperinflammatory conditions resulting in mortality in Indian patients. The study is published on the preprint server, medRxiv*.

25 Jan 2021

High density of street trees may help improve mental health

Depression, especially in urban areas, is on the rise, now more than ever. Mental health outcomes are influenced by, among other things, the type of environment where one lives.

25 Jan 2021

First-of-its-kind cardiovascular drug gets FDA approval based on study from Canadian VIGOUR Centre

The U.S. Food and Drug Administration has approved the drug vericiguat for use in patients with heart failure.

25 Jan 2021

Probiotics as adjuvant therapy for COVID-19 patients

In a recent review published in the Journal of Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Luigi Santacroce and Francesco Inchingolo et al. address the many factors such as dysbiosis (imbalance in the microbiota) that could influence the SARS-CoV-2 infection course.

25 Jan 2021

Reducing loneliness may decrease suicidality risk among adolescents having depressed mothers

Children of mothers experiencing depressive symptoms are more at risk, as adolescents, of experiencing suicidal thoughts and attempting suicide.

25 Jan 2021

New SARS-CoV-2 variants resistant to convalescent sera and and monoclonal antibodies

Researchers studying the effect of convalescent sera and monoclonal antibodies from recovered patients found the UK and South African SARS-CoV-2 variants are more resistant to neutralization compared to the wild-type virus.

25 Jan 2021

Study shows link between early brainstem tau accumulation and cortical hyperexcitability

Study conducted by researchers from the GIGA CRC In vivo Imaging laboratory at ULiège demonstrates, for the first time in humans, how the first deposits of tau proteins in the brainstem are associated with neurophysiological processes specific to the early stages of Alzheimer's disease development.

25 Jan 2021

New drug screening platform identifies inhibitors of SARS-CoV-2

Researchers in the UK and the United States have developed a stem-cell-based screening platform for identifying compounds that inhibit infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent for coronavirus disease 2019 (COVID-19).

25 Jan 2021

UK COVID-19 death to case ratio increased in December 2020, say researchers

Researchers in Scotland have conducted a study showing that the proportion of deaths due to coronavirus disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) increased in the UK after November 2020.

25 Jan 2021

Study finds high prevalence of cardiovascular conditions in male breast cancer patients

Male breast cancer patients were found to have a high prevalence of cardiovascular conditions, in a small study of this rare patient population presented at the American College of Cardiology's Advancing the Cardiovascular Care of the Oncology Patient Virtual course.

25 Jan 2021

Scientists develop a model to track viral load in COVID-19 patients

Scientists from the University of Alberta, Canada, have developed a model to determine patient-specific viral load curves for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The data obtained from this model can be used in other higher-level models to evaluate the physiological and pathological impacts of virus infection and determine patient risks.

25 Jan 2021

Medical Research News

SARS-CoV-2 rapidly adapts to Vero E6 cell culture propagation

Study shows several peridomestic mammal species are potential spreaders of SARS-CoV-2

New UK SARS-CoV-2 variant circulating in US since November, says study

New SARS-CoV-2 variant must be curbed to protect UK health services, warn experts

Accelerating vaccine rollout may provide greatest reduction in COVID-19 mortality

Recombinant SARS-CoV-2 protein vaccine less immunogenic but more antigenic than expected

B.1.1.7 variant and healthcare workers’ travel worry

Research shows immediate phase of blood vessel restructuring after aneurysm

Optimistic pupils with 'happy' memories linked to lower drink and drug risk

Hyperinflammatory conditions drive gender differences in COVID-19 severity and mortality

High density of street trees may help improve mental health

First-of-its-kind cardiovascular drug gets FDA approval based on study from Canadian VIGOUR Centre

Probiotics as adjuvant therapy for COVID-19 patients

Reducing loneliness may decrease suicidality risk among adolescents having depressed mothers

New SARS-CoV-2 variants resistant to convalescent sera and and monoclonal antibodies

Study shows link between early brainstem tau accumulation and cortical hyperexcitability

New drug screening platform identifies inhibitors of SARS-CoV-2

UK COVID-19 death to case ratio increased in December 2020, say researchers

Study finds high prevalence of cardiovascular conditions in male breast cancer patients

Scientists develop a model to track viral load in COVID-19 patients

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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