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Stopping RAS inhibitors linked to risk of adverse outcomes in patients with chronic kidney disease

Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients.

29 Dec 2020

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether. This is called chromosomal instability, and scientists at Memorial Sloan Kettering have learned that it is associated with cancer's aggressiveness.

28 Dec 2020

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

A new study led by clinician-scientists from the National Cancer Centre Singapore, with collaborators from research institutions worldwide, has found that angiosarcomas have unique genomic and immune profiles which allow them to be classified into three different subtypes.

28 Dec 2020

New studies uncover link between vaping and mental fog

Two new studies from the University of Rochester Medical Center have uncovered an association between vaping and mental fog. Both adults and kids who vape were more likely to report difficulty concentrating, remembering, or making decisions than their non-vaping, non-smoking peers.

28 Dec 2020

Dr. Genova wins K18 award to advance research on transition-age youth with autism

Helen M. Genova, PhD, of Kessler Foundation, was awarded a two-year K18 grant for $266,988 from the NIH's National Institute of Mental Health - the NIMH Career Enhancement Award to Advance Autism Services Research for Adults and Transition-Age Youth.

28 Dec 2020

Study identifies the effects of malnutrition on patient survival after cardiac surgery

Nutrients are the structural components of food that the body needs to function properly. They are divided into macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins, provitamins, various minerals, and so on). Their shortage is called nutritional deficiency.

28 Dec 2020

Model to assess the effect of lockdowns has fundamental shortcomings

In a recent study, researchers from Imperial College London developed a model to assess the effect of different measures used to curb the spread of the coronavirus.

28 Dec 2020

Popular glucose-lowering drug may cause rare diabetes complication in COVID-19 patients

Diabetes is a known risk factor for morbidity and mortality related to COVID-19. In diabetes patients, rare but severe complications, like the potentially lethal condition diabetic ketoacidosis (DKA), can arise when illness or certain conditions prevent cells from receiving enough glucose to fuel their functioning.

28 Dec 2020

Surgery may increase length of survival for metastatic breast cancer patients

Surgery, in addition to treatments like chemotherapy and radiation therapy, may increase the length of survival for metastatic breast cancer patients, according to Penn State College of Medicine and Penn State Cancer Institute researchers.

28 Dec 2020

Scientists decode music-evoked emotions in the brain

Researchers at the University of Turku have discovered what type of neural mechanisms are the basis for emotional responses to music.

28 Dec 2020

Kessler Foundation researcher receives grant to study emotional processing deficits in children with TBI

Jean Lengenfelder, PhD, of Kessler Foundation, received a two-year $168,001 grant from the New Jersey Commission on Brain Injury Research to study the impact of traumatic brain injury (TBI) on the ability of children to reliably process the emotions of others.

24 Dec 2020

Severity of COVID-19 correlates with the ratio of antibodies targeting crucial viral protein

COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine.

24 Dec 2020

SARS-CoV-2 spike-antibody binding strength and hydrogen bond numbers are temperature dependent, study finds

A new preprint on the bioRxiv* server describes the interactions between the binding spike protein of the SARS-CoV-2 virus with the antibodies. Earlier studies have addressed the similarity in the 3D structures of the spike protein in the two SARS viruses as seen on cryo-EM.

24 Dec 2020

Could engineered red blood cells be an effective antiviral against SARS-CoV-2?

In a new study, released on the bioRxiv* preprint server, a team of researchers explores the antiviral potential of red blood cells against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19.

24 Dec 2020

Animal study suggests palmitoylation inhibitor reduces virulence of SARS-CoV-2

A new study preprint on the bioRxiv* server demonstrates the ability of a fatty acid synthase inhibitor to improve the survival of mice infected with murine hepatitis virus. In so doing, it adds to the sum of knowledge about the relationship of SARS-CoV-2 with cholesterol metabolism in the host cell.

24 Dec 2020

Anti-SARS-CoV-2 NTD-directed antibodies are protective against lethal infection

As the world struggles to contain the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for over 1.6 million deaths and 76 million infections globally, researchers are trying to pin down the determinants of lethality, of infectivity and of protection. Such data would help contain its spread and develop preventive and therapeutic antivirals and vaccines. A new preprint that appeared recently on the bioRxiv* server describes the high degree of protection afforded by antibodies that target the N-terminal domain (NTD) of the virus.

24 Dec 2020

Immunologic modeling of COVID-19 severity and chronicity

In a new study by researchers at Universidad de Costa Rica and other institutions, a bioinformatics approach is used to determine whether Chronic COVID-19 (CC) might have a distinct immunologic signature compared to the mild to moderate (MM) or the severe/critical COVID-19.

24 Dec 2020

Loss of taste and smell may be most reliable COVID-19 symptoms for digital surveillance

A team of researchers from various institutions in London, Israel, and the USA recently tested the existence of consistent links between COVID-19 symptoms and SARS-CoV-2 test status in 3 national surveillance platforms.

24 Dec 2020

Mental disorders highly prevalent during coronavirus pandemics

Researchers in the United States have conducted an analysis showing the high prevalence of mental disorders across populations impacted by coronavirus pandemics.

24 Dec 2020

Reopening college campuses could initiate COVID-19 superspreading

Researchers at Stanford University in the United States have conducted a study showing that college campuses have an extremely high incidence of coronavirus disease 2019 (COVID-19) and that reopening them could initiate superspreading into neighboring communities.

24 Dec 2020

Medical Research News

Stopping RAS inhibitors linked to risk of adverse outcomes in patients with chronic kidney disease

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment

New studies uncover link between vaping and mental fog

Dr. Genova wins K18 award to advance research on transition-age youth with autism

Study identifies the effects of malnutrition on patient survival after cardiac surgery

Model to assess the effect of lockdowns has fundamental shortcomings

Popular glucose-lowering drug may cause rare diabetes complication in COVID-19 patients

Surgery may increase length of survival for metastatic breast cancer patients

Scientists decode music-evoked emotions in the brain

Kessler Foundation researcher receives grant to study emotional processing deficits in children with TBI

Severity of COVID-19 correlates with the ratio of antibodies targeting crucial viral protein

SARS-CoV-2 spike-antibody binding strength and hydrogen bond numbers are temperature dependent, study finds

Could engineered red blood cells be an effective antiviral against SARS-CoV-2?

Animal study suggests palmitoylation inhibitor reduces virulence of SARS-CoV-2

Anti-SARS-CoV-2 NTD-directed antibodies are protective against lethal infection

Immunologic modeling of COVID-19 severity and chronicity

Loss of taste and smell may be most reliable COVID-19 symptoms for digital surveillance

Mental disorders highly prevalent during coronavirus pandemics

Reopening college campuses could initiate COVID-19 superspreading

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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