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Children may transmit SARS-CoV-2 at same level as adults, suggests study

Researchers studied SARS-CoV-2 viral loads in over a thousand individuals, including both adults and children. They found the loads to be comparable, suggesting they may play an equal role in COVID-19 transmission.

5 Mar 2021

SARS-CoV-2 escapes host immune responses by modulating dendritic cell maturation

A team of scientists from Italy and the USA has recently explored the maturation pattern of conventional dendritic cells (cDCs) during SARS-CoV-2 infection.

5 Mar 2021

Researchers identify new molecular mechanisms in chronic skin inflammation

Frequently occurring chronic skin inflammation like in atopic dermatitis (AD or neurodermatitis) and psoriasis have different causes such as genetic predisposition, stress or allergens.

5 Mar 2021

One dose of SARS-CoV-2 vaccine candidate boosts neutralizing antibody response in COVID-19 convalescents

A new study details the results from a single dose of the FINLAY FR 1A recombinant dimeric receptor-binding domain (RBD) base vaccine during a phase I clinical trial with 30 COVID-19 convalescents to test its capacity for boosting natural immunity.

5 Mar 2021

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

A recent study reports the safety and high efficacy of an adjuvanted vaccine candidate against SARS-CoV-2 and the complications of COVID-19.

5 Mar 2021

SARS-CoV-2 proteins are potent suppressors of innate immunity

A new study describes the strong immune-suppressing activity of SARS-CoV-2 genes, among other coronavirus genes.

5 Mar 2021

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Scientists have recently developed a novel alternative molecular display technology called Molecular Indexing of Proteins by Self Assembly (MIPSA). Their research explains how this technology overcomes the critical disadvantages of PLATO and other full-length protein array technologies.

5 Mar 2021

Discovery offers a precise route to treat inflammation associated with neuropathic pain

One of the hallmarks of chronic pain is inflammation, and scientists at the UNC School of Medicine have discovered that anti-inflammatory cells called MRC1+ macrophages are dysfunctional in an animal model of neuropathic pain.

5 Mar 2021

UH pharmacologist to explore cause and treatment for left ventricular non-compaction cardiomyopathy

University of Houston pharmacologist Mingfu Wu has been awarded $2.5 million from the National Heart, Lung, and Blood Institute to explore the cause of and therapeutic treatment for left ventricular non-compaction cardiomyopathy (LVNC).

5 Mar 2021

Scientists seek to enhance artificial intelligence by integrating brain cells

With a new grant from the U.S. Army, a team of scientists will seek to enhance artificial intelligence by integrating brain cells called astrocytes.

5 Mar 2021

New evidence supports the use of antisense oligonucleotides as feasible therapeutic strategy for MDS

Many cognitive neurodevelopmental disorders are a result of too many or too few copies of certain genes or chromosomes.

5 Mar 2021

Research reveals major drivers of increased nicotine and tobacco use during COVID-19 lockdown

Pandemic-related anxiety, boredom, and irregular routines were cited as major drivers of increased nicotine and tobacco use during the initial COVID-19 "lockdown," according to research just released by Columbia University's Mailman School of Public Health.

5 Mar 2021

Unstable initiation by young people to working life is linked with poorer mental health

A new study reveals that a precarious, unstable initiation by young people to working life is associated with poorer future mental health.

5 Mar 2021

Study highlights urgent need to monitor legal wildlife trade to reduce emerging zoonotic diseases

With three out of four newly emerging infectious human diseases originating in animals, there is an urgent need to monitor the legal trade in wildlife, according to new research by Vincent Nijman, Professor in Anthropology at Oxford Brookes University.

5 Mar 2021

Real-time fMRI neurofeedback offers a novel treatment method for psychiatric illness

In recent years, researchers have begun using functional magnetic resonance imaging (fMRI) not just for better understanding the neural bases of psychiatric illness, but also for experimental treatment of depression, ADHD, anxiety, PTSD, substance use disorder, and schizophrenia with a technique called real-time fMRI neurofeedback.

5 Mar 2021

Study reveals close link between Parkinson's disease and certain immune cells in the blood

Parkinson's disease has always been considered a brain disorder. However, new research reveals a close link between the disease and certain immune cells in the blood.

4 Mar 2021

COVID-19 lockdown has significantly increased loneliness, social issues among women

Social distancing guidelines have reduced the spread of COVID-19, but lockdowns and isolation also have created or aggravated other well-being concerns, reports new research.

4 Mar 2021

Failing to communicate COVID-19 vaccine uncertainties has negative consequences

All healthcare decisions come with uncertainty. In addition to the general risks that a healthcare professional is aware of, there is also uncertainty surrounding the associated probabilities, called ambiguity or radical uncertainties. These uncertainties grow as vaccines generated at an unprecedented pace are administered across the world.

4 Mar 2021

Preclinical study finds immune benefit in unrefrigerated Soligenix coronavirus vaccines

A new study reports positive outcomes from two new vaccine candidates. The research, led by Axel T. Lehrer from the University of Hawaii at Manoa, studied mice's immune response when administered the CoVaccine HT adjuvant with an insect-cell expressed SARS-CoV-2 spike protein ectodomain.

4 Mar 2021

Study explains how the B.1.1.7 SARS-CoV-2 variant is more transmissible

New research led by Thushan I. de Silva from the University of Sheffield proposes that increases in subgenomic RNA (sgRNA) expression cause increased viral transmissibility and subsequent infection. They suggest the ORF9 protein, found in high amounts of sgRNA, could be regulating interferon responses.

4 Mar 2021

Medical Research News

Children may transmit SARS-CoV-2 at same level as adults, suggests study

SARS-CoV-2 escapes host immune responses by modulating dendritic cell maturation

Researchers identify new molecular mechanisms in chronic skin inflammation

One dose of SARS-CoV-2 vaccine candidate boosts neutralizing antibody response in COVID-19 convalescents

A SARS-CoV-2 spike protein adjuvant vaccine candidate produces durable rapid protection in vivo

SARS-CoV-2 proteins are potent suppressors of innate immunity

Identification of neutralizing IFNL3 autoantibodies in severe COVID-19 cases

Discovery offers a precise route to treat inflammation associated with neuropathic pain

UH pharmacologist to explore cause and treatment for left ventricular non-compaction cardiomyopathy

Scientists seek to enhance artificial intelligence by integrating brain cells

New evidence supports the use of antisense oligonucleotides as feasible therapeutic strategy for MDS

Research reveals major drivers of increased nicotine and tobacco use during COVID-19 lockdown

Unstable initiation by young people to working life is linked with poorer mental health

Study highlights urgent need to monitor legal wildlife trade to reduce emerging zoonotic diseases

Real-time fMRI neurofeedback offers a novel treatment method for psychiatric illness

Study reveals close link between Parkinson's disease and certain immune cells in the blood

COVID-19 lockdown has significantly increased loneliness, social issues among women

Failing to communicate COVID-19 vaccine uncertainties has negative consequences

Preclinical study finds immune benefit in unrefrigerated Soligenix coronavirus vaccines

Study explains how the B.1.1.7 SARS-CoV-2 variant is more transmissible

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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