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Rethinking the mitochondrial theory of aging

The human genome is broadly classified into the genome residing in the cell nucleus (nuclear DNA) and the genome residing in the mitochondria (mitochondrial DNA: mtDNA). Mitochondria are cell organelles that produce energy essential for life activities through oxidative phosphorylation (mitochondrial respiration), and mtDNA encodes a set of genes required for mitochondrial respiration.

27 May 2025

Alzheimer’s blood biomarkers predict faster muscle strength loss in older adults

A large Swedish cohort study found that elevated blood biomarkers associated with Alzheimer’s disease—including p-tau217, p-tau181, neurofilament light chain, and GFAP—predict accelerated muscle strength decline over 12 years in dementia-free older adults. These findings suggest that early identification of Alzheimer’s-related biomarkers could help clinicians intervene sooner to prevent sarcopenia and related adverse outcomes in aging populations.

27 May 2025

Understanding cow’s milk allergy in breastfed infants

Cow’s milk allergy (CMA) affects up to 2.2% of infants, with a complex interplay of immunological mechanisms, allergen transfer via breast milk, and variable responses to maternal elimination diets. Current evidence challenges the routine use of maternal dietary restrictions, highlighting the need for precise diagnosis and further research.

27 May 2025

Firmicutes bacteria can help maintain bone mass, study suggests

A recent study involving 684 Chinese adults has uncovered a significant connection between gut microbiota, aging, and bone health, particularly in relation to osteoporosis, a condition that weakens bones and increases the risk of fractures.

27 May 2025

Scientists make major progress toward an effective HIV vaccine

In the long battle to create an effective HIV vaccine, scientists have made a major leap forward. A new study shows that a series of vaccines can coax the immune system to produce powerful antibodies capable of blocking a wide range of HIV strains-including those that are typically the hardest to stop.

27 May 2025

Mild breast tenderness and swelling found to be part of healthy menstrual cycles

A one-year study in healthy women who were also consistently cycling every 21-36 days and had normal ovulation, showed that it is usual to experience mild breast tenderness and swelling before the next period.

27 May 2025

Researchers identify key nerve cells behind semaglutide's appetite reduction

A specific group of nerve cells in the brain stem appears to control how semaglutide affects appetite and weight – without causing nausea.

27 May 2025

New clinical practice guideline advances surgical care for chronic rhinosinusitis

The American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) published the new Clinical Practice Guideline (CPG): Surgical Management of Chronic Rhinosinusitis today in Otolaryngology–Head and Neck Surgery.

27 May 2025

Scientists discover unique molecular fingerprints of insulin resistance

Scientists have unearthed surprising details about how our bodies handle insulin – the hormone that plays a crucial role in regulating blood sugar and developing diabetes.

27 May 2025

Mental health among U.S. mothers declines sharply between 2016 and 2023

A new study published in JAMA Internal Medicine reveals a concerning decline in self-reported mental health among mothers in the United States between 2016 and 2023.

27 May 2025

Early statin therapy reduces heart attack and stroke risk in diabetes patients

Taking a statin medication is an effective, safe, and low-cost way to lower cholesterol and reduce risk of cardiovascular events.

27 May 2025

Healthcare utilization among the elderly remained stable in Japan despite pandemic challenges

Public healthcare emergencies, such as the COVID-19 pandemic, can drastically disrupt healthcare systems with long-term repercussions.

27 May 2025

New mothers experience severe loss of uninterrupted sleep after birth

A new study to be presented at the SLEEP 2025 annual meeting quantifies the amount of sleep loss experienced by first-time mothers in the weeks after giving birth and is the first to identify the unique type of sleep disruption that persists throughout the first months of motherhood.

27 May 2025

Optical stimulation of brain region boosts motor function in Parkinson’s models

Researchers are investigating the mechanisms and identifying new areas of the brain that can benefit patients when stimulated.

27 May 2025

New biomarker identified for predicting microvascular health of the kidneys

In a world first, Canadian scientists at the CRCHUM, the hospital research centre affiliated with Université de Montréal, have identified microRNA able to protect small blood vessels and support kidney function after severe injury.

27 May 2025

Early teen obesity in boys may affect the health of future generations

A new study suggests that boys who become overweight in their early teens risk damaging the genes of their future children, increasing their chances of developing asthma, obesity and low lung function.

27 May 2025

Abdominal fat emerges as independent risk factor for psoriasis in women

Researchers have found that central body fat, especially around the abdomen, is more strongly linked to psoriasis risk than total body fat, particularly in women.

27 May 2025

Global warming contributes to higher cancer mortality in women

Scientists have found that global warming in the Middle East and North Africa is making breast, ovarian, uterine, and cervical cancer more common and more deadly.

27 May 2025

MRI scans reveal why young women face higher risk for eating disorders

Advanced high-field MRI reveals distinct microstructural changes in hypothalamic subregions of young women with anorexia nervosa and obesity. These alterations may underlie increased vulnerability to eating disorders and point toward new neurobiological treatment targets.

26 May 2025

Which diet lowers blood pressure more: keto or Mediterranean?

A pilot study comparing a low-calorie, high-protein ketogenic diet and a Mediterranean diet in overweight and obese adults with elevated blood pressure found that both diets led to significant weight loss, improved body composition, and reduced blood pressure. Both dietary approaches were safe and well-tolerated, but the Mediterranean diet group showed a greater proportion of participants with healthy nocturnal blood pressure dipping.

26 May 2025