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Replication of SARS-CoV-2 in nasal ciliated cells could provide a new vaccination target

Researchers have found that nasal ciliated cells are targeted at the onset of COVID-19 infection, which may help to establish nasal mucosal immunity.

2 Jul 2021

New PET imaging method tracks immunotherapeutic efficacy in mouse models

Several cancer tumors grow through immunosuppression; that is, they manipulate biological systems in their microenvironments and signal to a specific set of immune cells--those that clear out aberrant cells--to stop acting. It is no wonder that immunotherapy designed to re-establish anti-tumor immunity is rapidly becoming the treatment of choice for these cancers.

2 Jul 2021

Extreme longevity likely to rise slowly by the end of the 21st century

The number of people who live past the age of 100 has been on the rise for decades, up to nearly half a million people worldwide.

2 Jul 2021

Researchers seek to quantify immunogenicity of COVID vaccines in immunocompromised patients

Evidence continues to mount that vaccination against COVID-19, most notably the Pfizer and Moderna vaccines, produces robust, durable protection in the vast majority of recipients.

2 Jul 2021

Immunity to SARS-CoV-2 could last longer than originally believed

One year after infection by SARS-CoV-2, most people maintain anti-Spike antibodies regardless of the severity of their symptoms, according to a study with healthcare workers co-led by the Barcelona Institute for Global Health (ISGlobal), the Catalan Health Institute (ICS) and the Jordi Gol Institute (IDIAP JG), with the collaboration of the Daniel Bravo Andreu Private Foundation.

2 Jul 2021

Study evaluates the difference in weight loss caused by two antidiabetic medications

Patients with Type 2 diabetes who were prescribed SGLT2 inhibitors lost more weight than patients who received GLP-1 receptor agonists, according to a University at Buffalo-led study.

2 Jul 2021

Research associates prior encounter with seasonal coronavirus to milder COVID-19 symptoms

A study by Stanford University School of Medicine investigators hints that people with COVID-19 may experience milder symptoms if certain cells of their immune systems "remember" previous encounters with seasonal coronaviruses -- the ones that cause about a quarter of the common colds kids get.

2 Jul 2021

Is there a link between circadian rhythms and COVID-19 severity?

This study showed that the time of day of SARS-CoV-2 infection could impact the severity of the viral infection and the host immune response.

1 Jul 2021

Engineered T cells prevent translational shutdown in SARS-CoV-2 infected cells

In a paper recently uploaded to the preprint server bioRxiv* by Schamel et al. (June 25th, 2021) engineered T cells against SARS-CoV-2 are tested against a range of cells in vitro, finding that the treatment could be used to restore cellular immune function and suppress SARS-CoV-2.

1 Jul 2021

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

A team of researchers recently demonstrated that mutations in the S protein of SARS-CoV-2 select for amino acid changes that result in a more stable protein than would otherwise be expected.

1 Jul 2021

Cryo-EM structure of neutralizing antibody 5-7 in complex with SARS CoV-2 spike

Researchers from the US recently reported the 3.7 Å resolution cryo-EM structure of an NTD-directed neutralizing antibody 5-7 that forms a complex with SARS-CoV-2 spike protein. They also presented the neutralization data against VOC and studied the recognized epitope.

1 Jul 2021

Mustard seed, wall rocket and turmeric extracts show potential against SARS-CoV-2 in vitro

Researchers in Spain have identified plant extracts that may be of interest in the search for treatments of coronavirus disease 2019 (COVID-19) and serve as a basis for future chemical, in vivo, and clinical trials.

1 Jul 2021

Grapevine leaf extract inhibits SARS-CoV-2 and HSV-1 replication in the lab

Researchers in Italy have shown that leaf extract from the common grapevine – Vitis vinifera – exhibits significant antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

1 Jul 2021

Medical Research News

Replication of SARS-CoV-2 in nasal ciliated cells could provide a new vaccination target

New PET imaging method tracks immunotherapeutic efficacy in mouse models

Extreme longevity likely to rise slowly by the end of the 21st century

Researchers seek to quantify immunogenicity of COVID vaccines in immunocompromised patients

Immunity to SARS-CoV-2 could last longer than originally believed

Study evaluates the difference in weight loss caused by two antidiabetic medications

Research associates prior encounter with seasonal coronavirus to milder COVID-19 symptoms

Is there a link between circadian rhythms and COVID-19 severity?

Engineered T cells prevent translational shutdown in SARS-CoV-2 infected cells

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

Cryo-EM structure of neutralizing antibody 5-7 in complex with SARS CoV-2 spike

Mustard seed, wall rocket and turmeric extracts show potential against SARS-CoV-2 in vitro

Grapevine leaf extract inhibits SARS-CoV-2 and HSV-1 replication in the lab

Smell loss patients are being failed by healthcare professionals, study reveals

Plastic drapes lower the incidence of hypothermia in very low birth-weight neonates

Pandemic prompts scientists at Cincinnati Children's to focus on suicide prevention research efforts

Study: Valvular heart disease in patients with chronic heart failure has been underestimated

Lung cancer patients should be screened for MET oncogene amplification, research suggests

Study finds a neural circuit for spirituality and religiosity

Patients' socioeconomic status can influence the medical assistance in dying

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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