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New study may lead to therapeutic strategies for chronic lung disease

Scientists at Washington University School of Medicine in St. Louis have implicated a type of immune cell in the development of chronic lung disease that sometimes is triggered following a respiratory viral infection.

10 Mar 2021

Researchers discover new COVID-19 variants in three South African provinces

Variants of the coronavirus are appearing in different parts of the world, many of them spreading with alarming speed.

10 Mar 2021

Both ventral and dorsal surgeries improve outcomes in patients with cervical spondylotic myelopathy

Affecting the vast majority of people older than 65, cervical spondylotic myelopathy (CSM) is the leading cause of spinal cord dysfunction in the United States and across the world.

10 Mar 2021

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

In a recent bioRxiv* preprint paper, researchers isolated anti-RBD nanobodies from llamas and “nanomice” (they engineered to produce VHHs cloned from alpacas, dromedaries and camels).

10 Mar 2021

Analysis shows moderate evidence for SARS-CoV-2 recombination

Recently, a team of researchers from the US performed a comprehensive recombination analysis across all medically relevant human coronaviruses, including 158,118 public seasonal hCoV, SARS-CoV-1, SARS-CoV-2, and MERS-CoV genome sequences with the help of the RDP4 software. They aimed at identifying the current and future risks of the emergence of recombinants of SARS-CoV-2

10 Mar 2021

Women with gestational diabetes lack perceived risk of developing type 2 diabetes

While it's an unfair reality that women who develop gestational diabetes are ten times more likely to develop type 2 diabetes later in life, only a third of these women realize that they're at high risk, according to new research by the University of South Australia.

9 Mar 2021

New tumor-penetrating therapy may improve outcomes in patients with pancreatic cancer

Every 12 minutes, someone in the United States dies of pancreatic cancer, which is often diagnosed late, spreads rapidly and has a five-year survival rate at approximately 10 percent.

9 Mar 2021

2% of individuals carry 90% of SARS-CoV-2 virions: Study of 72,500 tests

In a new study published on the medRxiv* preprint server, researchers analyzed viral loads from pre-symptomatic and asymptomatic individuals in an extensive university surveillance program.

9 Mar 2021

SARS-CoV-2 variants rapidly arise in non-human hosts, potential risk for human reinfection

The study, published on the preprint server bioRxiv*, highlights the need to study viral evolution and pathogenesis in human and animal hosts. This could help prevent future outbreaks that may mimic the magnitude of the current COVID-19 pandemic.

9 Mar 2021

Scientists study seven human coronavirus envelope proteins using topology prediction and molecular modeling

A new study by researchers at the University of the Western Cape aimed to determine why some coronaviruses are more virulent than others. The team speculates that the increased flexibility of the PDZ-binding motif (PBM) of SARS-CoV, MERS-CoV, and SARS22 CoV-2 to be more flexible than the PBM of hCoVs 229E, NL63, OC43, and HKU1.

9 Mar 2021

Study reveals novel approach to reduce the risk of thrombosis by using IgM antibodies

Thrombotic occlusion of blood vessels, which leads to myocardial infarctions, strokes and venous thromboembolisms, is the major cause of death in the western hemisphere.

9 Mar 2021

Study finds reduction in pediatric emergency visits, hospitalizations during the pandemic

Amid the COVID-19 pandemic, children's hospitals across the United States have seen signification reductions in the number of children being treated for common pediatric illnesses like asthma and pneumonia, according to a new multicenter study led by Monroe Carell Jr. Children's Hospital at Vanderbilt.

9 Mar 2021

New analysis shows SARS-CoV-2 mutations rarely persist in subsequent transmissions

An analysis of SARS-CoV-2 genome diversity in more than 1,000 people in the United Kingdom suggests that if viral mutations do arise, they can be transmitted in some cases but they rarely persist in subsequent transmissions.

9 Mar 2021

Vaccine mRNA not found in breast milk after COVID mRNA vaccination

A study conducted by researchers in the United States has found no evidence to suggest that the messenger RNA (mRNA) present in the Pfizer-BioNTech and Moderna vaccines that protect against coronavirus disease 2019 (COVID-19) can be transferred to human breast milk.

9 Mar 2021

UK variant of SARS-CoV-2 could be more deadly than previous strains

Researchers have conducted a study showing that the B.1.1.7 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has emerged in the UK is associated with a significantly increased risk of death compared with the viral strain previously circulating in the country.

9 Mar 2021

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Schizophrenia is a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. Researchers have long searched for genetic influences in the disease, but genetic mutations have been identified in only a small fraction--fewer than a quarter--of sequenced patients.

9 Mar 2021

Sugar-sweetened soda intake associated with increased risk of mortality among breast cancer patients

New research from the University at Buffalo suggests that breast cancer patients who drink sugar-sweetened beverages regularly are at increased risk for death from any cause and breast cancer in particular.

9 Mar 2021

Study examines effects of problematic internet use on older adolescents

Most teenagers don't remember life before the internet. They have grown up in a connected world, and being online has become one of their main sources of learning, entertaining and socializing.

9 Mar 2021

Translational research results in promising combination therapeutic candidate for type 1 diabetes

Translational research led by scientists at La Jolla Institute for Immunology (LJI) has resulted in a promising combination therapeutic candidate for adults with recent-onset type 1 diabetes.

9 Mar 2021

Buck scientists develop a predictive model to help identify people at risk for severe COVID-19

Researchers at the Buck Institute analyzed data from the COVID-19 Symptom Tracker app used by 3 million people in the United Kingdom, adding the use of immunosuppressant medication, use of a mobility aid, shortness of breath, fever, and fatigue to the list of symptoms and comorbidities that increase the risk for severe COVID-19.

9 Mar 2021

Medical Research News

New study may lead to therapeutic strategies for chronic lung disease

Researchers discover new COVID-19 variants in three South African provinces

Both ventral and dorsal surgeries improve outcomes in patients with cervical spondylotic myelopathy

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

Analysis shows moderate evidence for SARS-CoV-2 recombination

Women with gestational diabetes lack perceived risk of developing type 2 diabetes

New tumor-penetrating therapy may improve outcomes in patients with pancreatic cancer

2% of individuals carry 90% of SARS-CoV-2 virions: Study of 72,500 tests

SARS-CoV-2 variants rapidly arise in non-human hosts, potential risk for human reinfection

Scientists study seven human coronavirus envelope proteins using topology prediction and molecular modeling

Study reveals novel approach to reduce the risk of thrombosis by using IgM antibodies

Study finds reduction in pediatric emergency visits, hospitalizations during the pandemic

New analysis shows SARS-CoV-2 mutations rarely persist in subsequent transmissions

Vaccine mRNA not found in breast milk after COVID mRNA vaccination

UK variant of SARS-CoV-2 could be more deadly than previous strains

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Sugar-sweetened soda intake associated with increased risk of mortality among breast cancer patients

Study examines effects of problematic internet use on older adolescents

Translational research results in promising combination therapeutic candidate for type 1 diabetes

Buck scientists develop a predictive model to help identify people at risk for severe COVID-19

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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