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Novel 3D maps show how genes interact in several types of immune cells

The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.

22 Dec 2020

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Immune inflammatory mediators are critical in pathology, transplantation, and regenerative medicine, scientists report in The American Journal of Pathology

22 Dec 2020

Researchers detect novel IRAK4 mutations in infant with encephalitis and HHV6 reactivation

An infant's odd case of rare encephalitis not typically found in children led researchers to discover never before seen genetic mutations and a more accurate technique to examine the IRAK4 gene responsible for innate immunity.

22 Dec 2020

Study sheds new light on immune system interactions with cancer

Cancers like melanoma are hard to treat, not least because they have a varied bag of tricks for defeating or evading treatments.

21 Dec 2020

Researchers have a promising lead on COVID-19 treatment

By taking a lesson from prostate cancer, researchers now have a promising lead on treatment for COVID-19. Two proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, M.D., Ph.D. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers. They also knew that TMPRSS2 was regulated by the androgen receptor.

21 Dec 2020

Study depicts previously unknown molecular mechanism underlying healthy brain development

A research team led by Michael Fox, a professor at the Fralin Biomedical Research Institute at VTC, has identified the type of brain cell that produces collagen 19, a protein that is crucial for the formation of inhibitory circuits in the brain.

21 Dec 2020

Reston virus causes severe respiratory disease in piglets

Reston ebolavirus (RESTV) should be considered a livestock pathogen with potential to affect other mammals, including people, according to National Institutes of Health scientists.

21 Dec 2020

Nocturnal respiratory rate of heart patients can help predict the success of ICD treatment

onditions causing arrhythmia are among the most common cardiac conditions. A study headed by Prof. Georg Schmidt of the Technical University of Munich has demonstrated for the first time that the nocturnal respiratory rate can help with an important prediction: It is an indicator of whether a defibrillator will help to extend the life of patients with arrhythmia.

21 Dec 2020

Researchers explore why seizures happen in a subset of MS patients

A research team at the University of California, Riverside School of Medicine has identified a pathway involving astrocytes, a class of central nervous system support cells, that could shed light on why seizures happen in a subset of multiple sclerosis, or MS, patients.

21 Dec 2020

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

The absence of a protein that works to prevent tumor formation may explain why some patients are resistant to a common cancer therapy, according to Penn State College of Medicine researchers.

21 Dec 2020

Sex-specific difference could prevent Alzheimer's treatment from working in females

A University of Ottawa study has found a specific Alzheimer's treatment is effective in male and not female mice, providing a window into the biology of the disease and the effectiveness of targeted treatments.

21 Dec 2020

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

21 Dec 2020

Brain tissue analysis may help explain enduring mysteries about PTSD

A post-mortem analysis of brain tissue from people who had been diagnosed with post-traumatic stress disorder (PTSD) may help explain enduring mysteries about the disorder, such as why women are more susceptible to it and whether a dampened immune system response plays a role in dealing with stress, a team headed by Yale University researchers has found.

21 Dec 2020

Moffitt study may lead to potential treatment options for cutaneous T cell lymphoma

Cutaneous T cell lymphomas (CTCLs) are a group of non-Hodgkin lymphomas that develop from T cells and mainly impact the skin with painful lesions.

21 Dec 2020

Community-level intervention can reduce alcohol-impaired driving and consequences

New research from the Prevention Research Center of the Pacific Institute for Research and Evaluation shows that a community-level alcohol intervention in California resulted in a 17% reduction in alcohol-involved crashes among drivers aged 15-30.

21 Dec 2020

Arthritis drug may be effective in treating immunotherapy-related heart complication

A drug typically prescribed for rheumatoid arthritis may also be effective in treating a rare but potentially deadly heart complication some cancer patients experience after taking immunotherapies, according to a study published in Cancer Discovery and co-led by investigators at Vanderbilt University Medical Center.

21 Dec 2020

Cannabis use during opioid addiction treatment may reduce fentanyl exposure

New research suggests that cannabis use by people in care for opioid addiction might improve their treatment outcomes and reduce their risk of being exposed to fentanyl in the contaminated unregulated drug supply.

21 Dec 2020

COVID-19: Meta-analysis unveils adversely affected biological processes in infected lung cells

The researchers Wasco Wruck and Prof. James Adjaye from the Institute of Stem Cell Research and Regenerative Medicine, Medical Faculty of Heinrich-Heine-University Duesseldorf, Germany, employed a bioinformatic approach on transcriptome data pertaining to human lung epithelial cells infected with SARS-CoV-2.

21 Dec 2020

COVID-19 contact tracing ineffective without timely testing and isolation, study says

A new study by Canada-based researchers has showed that contact tracing is not effective if testing and isolation are delayed.

21 Dec 2020

Nearly half of US hospitals have reached critical care capacity, study finds

A new study by researchers at the Harvard T.H. Chan School of Public Health and Brown University shows that about half of US hospitals have reported reaching critical capacity since September, illustrating the scale of the coronavirus pandemic’s ‘second wave’ and the burden of pressure it has placed on the nation’s healthcare.

21 Dec 2020

Medical Research News

Novel 3D maps show how genes interact in several types of immune cells

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Researchers detect novel IRAK4 mutations in infant with encephalitis and HHV6 reactivation

Study sheds new light on immune system interactions with cancer

Researchers have a promising lead on COVID-19 treatment

Study depicts previously unknown molecular mechanism underlying healthy brain development

Reston virus causes severe respiratory disease in piglets

Nocturnal respiratory rate of heart patients can help predict the success of ICD treatment

Researchers explore why seizures happen in a subset of MS patients

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

Sex-specific difference could prevent Alzheimer's treatment from working in females

Researchers demonstrate potential preventive treatment for Crohn's disease

Brain tissue analysis may help explain enduring mysteries about PTSD

Moffitt study may lead to potential treatment options for cutaneous T cell lymphoma

Community-level intervention can reduce alcohol-impaired driving and consequences

Arthritis drug may be effective in treating immunotherapy-related heart complication

Cannabis use during opioid addiction treatment may reduce fentanyl exposure

COVID-19: Meta-analysis unveils adversely affected biological processes in infected lung cells

COVID-19 contact tracing ineffective without timely testing and isolation, study says

Nearly half of US hospitals have reached critical care capacity, study finds

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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