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Researchers develop an electroceutical for preterm labor detection and treatment

Preterm labor comprises 12.7% of all pregnancies. Although the overall rate of pregnancy is decreasing, the occurrence of premature birth due to preterm labor in south korea has been increasing over the past 7 years.

26 Feb 2021

UNH receives $2.97 million in grants to investigate the effectiveness of wilderness therapy

The University of New Hampshire's Outdoor Behavioral Healthcare Center receives $2.97 million in grants to conduct a first-of-its-kind randomized study looking at the effectiveness of outdoor behavioral health (OBH), or wilderness therapy, a prescriptive treatment for teens struggling with depression, anxiety and substance use disorders.

26 Feb 2021

Statin use associated with reduction in mortality of patients with severe COVID-19

People who took statins to lower cholesterol were approximately 50% less likely to die if hospitalized for COVID-19, a study by physicians at Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian has found.

26 Feb 2021

New seizure predicting mathematical model gives accurate warning to epilepsy patients

Epilepsy is one of the most common neurological conditions, affecting more than 65 million worldwide. For those dealing with epilepsy, the advent of a seizure can feel like a ticking time bomb.

26 Feb 2021

Early PDA closure may reduce adverse outcomes in premature babies

Extremely low birth weight (ELBW) infants with moderate to large patent ductus arteriosus (PDA) may benefit from transcatheter PDA closure (TCPC) in the first four weeks of life, according to research published by Le Bonheur Cardiologist Ranjit Philip, MD, and Medical Director of Interventional Cardiac Imaging and Interventional Catheterization Laboratory Shyam Sathanandam, MD.

26 Feb 2021

Study finds novel way to diagnose Alzheimer's disease before symptoms occur

Early diagnosis of Alzheimer's disease has been shown to reduce cost and improve patient outcomes, but current diagnostic approaches can be invasive and costly.

26 Feb 2021

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

A new study by researchers in the U.S. further supports the hypothesis that the unregulated release of inflammatory cytokines is responsible for the local and systemic inflammation that is associated with multi-organ damage and death in severe COVID-19.

26 Feb 2021

South African SARS-CoV-2 variant partly resistant to neutralization by mRNA vaccine, says study

A new study deals with the clinical and virological effects of circulating SARS-CoV-2 variants, especially as they affect vaccine efficacy.

26 Feb 2021

Repurposed drugs show antiviral SARS-CoV-2 E channel blocking activity, finds study

A new study by researchers at The Hebrew University of Jerusalem in Israel reports the discovery of a promising group of E channel inhibitors with significant antiviral activity. This could be developed into new treatment agents for this often-deadly virus.

26 Feb 2021

Researchers develop new tool for predicting the effects of SARS-CoV-2 missense variants

A new study by a team of researchers in the UK and US describes the use of a computational tool that generates all possible single amino acid substitutions in SARS-CoV-2 and predicts their effects.

26 Feb 2021

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence

A new study by researchers at Brookhaven National Laboratory and Stony Brook University in the U.S. describes the key interaction between the viral envelope (E) protein and the human cell junction protein, PALS1. The latter is necessary to establish and maintain cell polarity and tight junctions between cells.

26 Feb 2021

Inhalable nanobody shows potent anti-SARS-CoV-2 activity in vivo

Researchers have developed a stable and ultrapotent homotrimeric Pittsburgh inhalable Nanobody 21 (PiN-21) against SARS-CoV-2 infection in Syrian hamsters. They demonstrated the high therapeutic efficacy of this homotrimeric Nb, leveraging both intranasal and aerosol delivery.

26 Feb 2021

Nanobowls show potential for diagnostics and treatment of Alzheimer's

Scientists are still a long way from being able to treat Alzheimer's Disease, in part because the protein aggregates that can become brain plaques, a hallmark of the disease, are hard to study.

26 Feb 2021

What is the impact of demographics and air quality on COVID-19 mortality?

A new piece of research was conducted using a wide range of variables related to demographic and environmental factors in New York State (NYS), USA. NYS consists of urban and ethnically diverse counties, some of which are population-dense while others are population-sparse.

26 Feb 2021

Is one dose of Pfizer-BioNTech mRNA vaccine for COVID-19 convalescents sufficient?

Researchers evaluated the immune response in a cohort of 1,089 healthcare workers who received the Pfizer-BioNTech vaccine in Southern California.

26 Feb 2021

Mandatory public health measures to combat COVID-19 are more effective, says study

In a new study, researchers at Lundberg Health Advocates and the Johns Hopkins Bloomberg School of Public Health in the U.S. compared mandatory and voluntary implementations of shelter-in-place policies. They assessed their respective bearings on COVID-19 mortality, equity, and economic outcomes.

26 Feb 2021

Immunologists map unknown biological machinery to produce memory T cells

Immunologists at St. Jude Children's Research Hospital have mapped the previously unknown biological machinery by which the immune system generates T cells that kill bacteria, viruses and tumor cells.

26 Feb 2021

Researchers investigate the duration of the immune response to SARS-CoV-2

The optimal timeframe for donating convalescent plasma for use in COVID-19 immunotherapy, which was given emergency use authorization by the Food and Drug Administration in August 2020, is within 60 days of the onset of symptoms, according to a new Penn State-led study.

26 Feb 2021

New approach can help treat hypertrophic cardiomyopathy with precision medicine

Hypertrophic cardiomyopathy (HCM) is a cardiovascular disease characterized by thickening of the left ventricle, otherwise known as the main squeezing chamber of the heart. HCM is best known for causing sudden death in athletes but can occur in persons of any age, often without symptoms.

26 Feb 2021

Study reveals information about risk genes in schizophrenia

Dr. Felix-Martin Werner, working at the Euro Academy Pößneck in Germany and Prof. Rafael Coveñas, working at the Institute of Neurosciences of Castilla and León, Salamanca in Spain, have been working on neurological and psychiatric disease for over ten years.

26 Feb 2021

Medical Research News

Researchers develop an electroceutical for preterm labor detection and treatment

UNH receives $2.97 million in grants to investigate the effectiveness of wilderness therapy

Statin use associated with reduction in mortality of patients with severe COVID-19

New seizure predicting mathematical model gives accurate warning to epilepsy patients

Early PDA closure may reduce adverse outcomes in premature babies

Study finds novel way to diagnose Alzheimer's disease before symptoms occur

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

South African SARS-CoV-2 variant partly resistant to neutralization by mRNA vaccine, says study

Repurposed drugs show antiviral SARS-CoV-2 E channel blocking activity, finds study

Researchers develop new tool for predicting the effects of SARS-CoV-2 missense variants

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence

Inhalable nanobody shows potent anti-SARS-CoV-2 activity in vivo

Nanobowls show potential for diagnostics and treatment of Alzheimer's

What is the impact of demographics and air quality on COVID-19 mortality?

Is one dose of Pfizer-BioNTech mRNA vaccine for COVID-19 convalescents sufficient?

Mandatory public health measures to combat COVID-19 are more effective, says study

Immunologists map unknown biological machinery to produce memory T cells

Researchers investigate the duration of the immune response to SARS-CoV-2

New approach can help treat hypertrophic cardiomyopathy with precision medicine

Study reveals information about risk genes in schizophrenia

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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