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Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Now, a new study presented on the preprint server bioRxiv in October 2020 describes the efficient design of an mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), based on the use of the viral receptor-binding domain (RBD) mRNA encapsulated in lipid nanoparticles (LNP).

19 Oct 2020

Study points out key variations in hospice transitions and experiences

Terminally ill patients referred to hospice care from a hospital setting tend to be on hospice for shorter periods than those who enter hospice while living at home or in a residential care facility.

19 Oct 2020

Scientists find striking acceleration in medieval plague transmission over 300 years

McMaster University researchers who analyzed thousands of documents covering a 300-year span of plague outbreaks in London, England, have estimated that the disease spread four times faster in the 17th century than it had in the 14th century.

19 Oct 2020

Antigenic imprinting of sarbecovirus

A recent study published on the preprint server bioRxiv* in October 2020 shows that the design of a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) must consider the prior history of exposure to coronaviruses since these affect the antibody response to the virus.

19 Oct 2020

Study finds dramatic increase in the use of non-invasive ventilation

More research is needed before a less invasive form of ventilation is used near the end of life for patients who have cancer and dementia, recommends the authors of a scientific paper published in JAMA Internal Medicine.

19 Oct 2020

Trend analysis in Japan reveals Creutzfeldt-Jakob disease may not be so rare anymore

Creutzfeldt-Jakob disease (CJD) is a debilitating disorder that causes rapid degeneration of the brain as well as progressing dementia.

19 Oct 2020

Study tackles the role of the renin-angiotensin system on COVID-19 pathophysiology

Vinicius Novaes Rocha, a researcher at the Federal University of Juiz de Fora in Brazil, provides an insight into the role of the renin-angiotensin on the pathophysiology of COVID-19, paving the way for developing new treatment methods in the journal Medical Hypotheses.

19 Oct 2020

Study finds direct link between physical fitness, cognitive performance, and optimal nutrition

Researchers at the University of Illinois, Urbana-Champaign, Abbott and, the U.S. Air Force Research Lab announced today the results of a new study that found a direct link between physical fitness, cognitive performance, and optimal nutrition.

19 Oct 2020

Untreated obstructive sleep apnea linked with increased hospitalization from flu

As we approach flu season, adults with obstructive sleep apnea may want to take extra precautions. A study published online as an accepted paper in the Journal of Clinical Sleep Medicine is the first to find that patients with sleep apnea who did not use CPAP therapy were more likely to be hospitalized with the flu.

19 Oct 2020

Scientists discover key enzyme involved in the development of autoimmune diseases

Scientists affiliated with the Center for Research on Inflammatory Diseases (CRID http://crid.fmrp.usp.br), hosted by the University of São Paulo (USP) in Brazil, have discovered that an enzyme involved in key metabolic processes also plays a role in immune cell differentiation and hence in the development of autoimmune diseases.

19 Oct 2020

Student adherence to control measures could significantly reduce COVID-19 risk

Researchers at the University of Warwick in the UK have conducted a modeling study showing that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could readily spread among students in the university setting if non-pharmaceutical interventions (NPIs) are not properly adhered to.

19 Oct 2020

New project to use plasma jets to decontaminate vital medical equipment exposed to Covid-19 virus

A NEW project developed by Lancaster University's Health Innovation Campus and Material Science Institute will see pioneering technology used to decontaminate vital medical equipment exposed to the Covid-19 virus, via a partnership with University Hospitals of Morecambe Bay NHS Foundation Trust.

19 Oct 2020

COVID-19 has increased the urgency of advanced care planning, WVU study shows

No one likes to think about their own mortality. But COVID-19 has shoved life's dark questions to the forefront: "What if I'm hooked to a ventilator and can't speak?" "If my heart stops beating, do I want to be resuscitated?" "Where do I want to die?"

19 Oct 2020

Melatonin may increase survival chances among intubated COVID-19 patients

Researchers at Columbia University in New York have conducted a study showing that patients with coronavirus disease 2019 (COVID-19) who require intubation and mechanical ventilation due to respiratory distress may benefit from treatment with the hormone melatonin.

19 Oct 2020

Temple researchers identify criteria to predict cytokine storm in COVID-19 patients

Like a cold front that moves in, setting the stage for severe weather, coronavirus infection triggers showers of infection-fighting immune molecules - showers that sometimes escalate into a chaotic immune response known as a cytokine storm.

19 Oct 2020

Study finds characteristics of nursing home residents more likely to be hospitalized after ED visit

Transfers from the nursing home to the emergency department (ED) or the hospital can have negative longer-term impact on the health of older adults.

19 Oct 2020

Immunoglobulin M ACE2 autoantibodies associated with severe COVID-19

As the COVID-19 pandemic progresses with little prospect of immediate relief, a recent study by Johns Hopkins University researchers published on the preprint server medRxiv* in October 2020 discusses the association of Immunoglobulin M (IgM) autoantibodies against the host receptor that binds severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with severe disease via vascular endothelial damage. This could help develop better therapies and prognostic criteria.

19 Oct 2020

Hydrogels and magnetic field could be used to rebuild complex body tissues

Using a magnetic field and hydrogels, a team of researchers in the Perelman School of Medicine at the University of Pennsylvania have demonstrated a new possible way to rebuild complex body tissues, which could result in more lasting fixes to common injuries, such as cartilage degeneration.

19 Oct 2020

Research could pave way for personalized cochlear implants

Cochlear implants are a groundbreaking technology that has changed the lives of many people living with severe to profound hearing loss.

19 Oct 2020

Perceived risk of COVID-19 infection increases likelihood of depression among people in Soweto

Associations between depression and issues such as hunger, violence, poor healthcare, and high rates of poverty have long been recognized, but this study is the first to look at the mental health effects of the pandemic and national lockdown in South Africa under those conditions.

19 Oct 2020

Medical Research News

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Study points out key variations in hospice transitions and experiences

Scientists find striking acceleration in medieval plague transmission over 300 years

Antigenic imprinting of sarbecovirus

Study finds dramatic increase in the use of non-invasive ventilation

Trend analysis in Japan reveals Creutzfeldt-Jakob disease may not be so rare anymore

Study tackles the role of the renin-angiotensin system on COVID-19 pathophysiology

Study finds direct link between physical fitness, cognitive performance, and optimal nutrition

Untreated obstructive sleep apnea linked with increased hospitalization from flu

Scientists discover key enzyme involved in the development of autoimmune diseases

Student adherence to control measures could significantly reduce COVID-19 risk

New project to use plasma jets to decontaminate vital medical equipment exposed to Covid-19 virus

COVID-19 has increased the urgency of advanced care planning, WVU study shows

Melatonin may increase survival chances among intubated COVID-19 patients

Temple researchers identify criteria to predict cytokine storm in COVID-19 patients

Study finds characteristics of nursing home residents more likely to be hospitalized after ED visit

Immunoglobulin M ACE2 autoantibodies associated with severe COVID-19

Hydrogels and magnetic field could be used to rebuild complex body tissues

Research could pave way for personalized cochlear implants

Perceived risk of COVID-19 infection increases likelihood of depression among people in Soweto

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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