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Studies reveal the promise of newly engineered bispecific antibodies against tumor cells

Three studies - one each in Science, Science Translational Medicine, and Science Immunology - reveal the promise of newly engineered bispecific antibodies, including by demonstrating their power against previously inaccessible tumor cell targets for the first time, in two cases.

2 Mar 2021

A single letter difference in a single gene spells a lifetime of anemia, pain worldwide

A single letter difference in a single gene, inherited from both parents, spells a lifetime of anemia and pain for 20 million people, mostly of African ancestry, worldwide.

2 Mar 2021

Graphene oxide-silver nanoparticles shown to rapidly neutralize RNA viruses

While the vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are administered, and extensive research is conducted for targeted therapeutics to control the COVID-19 (coronavirus disease 2019), it is equally crucial to develop more novel, broad-spectrum antiviral compounds.

2 Mar 2021

COVID-19 virus could be transmitted through fecal-contaminated river water

Scientists have identified that the COVID-19 virus could be transmitted through faecal contaminated river water.

2 Mar 2021

Study reveals the effect of digital devices on children's cognitive, socio-emotional development

What can you see in this picture (next to the article)? Say what comes to your mind immediately! If you said „star", you focus rather on the details, if you said „sun", then rather on the global pattern.

2 Mar 2021

Researchers focus on the role of human behavior to advance comfort knowledge

Comfort is a daily human experience central to the perception of our environment and the continuous processing of sensory input.

2 Mar 2021

Biological activity-based modeling offers a new approach for drug discovery

Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases.

2 Mar 2021

Scientists modify existing SIR class pandemic prediction model

A painful tradeoff between a number of infected and negative economic impact must be considered before deciding on the lockdown strategy within a city. As national economies continue to crumble, citizens wonder whether their governments did a good job at regulating the lockdown measures.

2 Mar 2021

Researchers discover new ingredient that has protective effects against Parkinson’s disease

Sesame seed oil, used by many for its nutty aroma and high burn-point, is made by extracting the fatty oils from sesame seeds, with the empty shells thrown out as waste. In a literal instantiation of the age-old adage "one man's trash is another man's treasure", researchers discovered that a chemical called sesaminol, abundant in this waste, has protective effects against Parkinson's disease.

2 Mar 2021

Researchers explore early stages of ribosome formation to identify new targets for antibiotics

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers from Charité - Universitätsmedizin Berlin have gained new insights into this multifaceted process.

2 Mar 2021

Researchers study the digestion process of drug-loaded DNA nanostructures in real time

DNA nanotechnology - the research field using DNA molecules as building material - has developed rapidly during recent years and enabled the construction of increasingly complex nanostructures.

2 Mar 2021

Loss of functions in the PLD1 gene causes congenital heart disease

A team of researchers co-led by Michael Frohman, MD, PhD, of Stony Brook University, has identified an important cause of congenital heart disease.

2 Mar 2021

Study shows how SARS-CoV-2 affects cytokines compared to other respiratory viruses

Respiratory viruses such as SARS-CoV-2 (causing COVID-19) can often catalyze an overactive immune response that leads to a life-threatening cycle, known as a cytokine storm.

2 Mar 2021

Study reveals presence of glial plasticity, offers future therapeutic strategy for epilepsy

Tohoku University scientists and their colleagues in Germany have revealed that a first-time exposure to only a brief period of brain hyperactivity resulted in an acute breakdown of the inter-cellular network of glial cells.

2 Mar 2021

Study shows asthma mediator IL-13 prevents SARS-CoV-2 infection

In a paper published on the bioRxiv preprint server, researchers reported the results on whether IL-13 expression in asthma patients reduces their susceptibility to SARS-CoV-2 infection.

1 Mar 2021

Emerging protein-based immunotherapies could lead to highly effective cancer treatments

In a new commentary for the journal Science, an associate vice president for research at The University of Texas at Arlington argues that emerging protein-based immunotherapies could lead to highly effective "off-the-shelf" cancer treatments for more patients.

1 Mar 2021

Scientists establish infection models for SARS-CoV-2 UK & South African variants

New research suggests Syrian golden hamsters could be a potentially useful preclinical model for testing vaccine immunity against the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.17 and B.1.351 variant.

1 Mar 2021

Enduring antibody response observed after natural immunity and first Pfizer SARS-CoV-2 vaccine shot

Immunity gained after natural infection from the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is boosted when people take the first Pfizer-BioNTech vaccine, according to a new study led by Iain C. Chapple from the University of Birmingham.

1 Mar 2021

Tier 3 interventions needed to contain SARS-CoV-2 transmission, especially with emergence of variants

Studies have shown that non-pharmaceutical interventions (NPIs) such as social distancing and partial lockdowns effectively contain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. However, because of these measures' huge economic and social cost, the UK introduced a less socially disruptive tier system. This system was aimed at providing a consistent set of control measures with geographic flexibility.

1 Mar 2021

School-based cavity prevention program reduces health disparities, brings dental care to children

A school-based cavity prevention program involving nearly 7,000 elementary school students reduced cavities by more than 50 percent, according to a study led by researchers at NYU College of Dentistry.

1 Mar 2021

Medical Research News

Studies reveal the promise of newly engineered bispecific antibodies against tumor cells

A single letter difference in a single gene spells a lifetime of anemia, pain worldwide

Graphene oxide-silver nanoparticles shown to rapidly neutralize RNA viruses

COVID-19 virus could be transmitted through fecal-contaminated river water

Study reveals the effect of digital devices on children's cognitive, socio-emotional development

Researchers focus on the role of human behavior to advance comfort knowledge

Biological activity-based modeling offers a new approach for drug discovery

Scientists modify existing SIR class pandemic prediction model

Researchers discover new ingredient that has protective effects against Parkinson’s disease

Researchers explore early stages of ribosome formation to identify new targets for antibiotics

Researchers study the digestion process of drug-loaded DNA nanostructures in real time

Loss of functions in the PLD1 gene causes congenital heart disease

Study shows how SARS-CoV-2 affects cytokines compared to other respiratory viruses

Study reveals presence of glial plasticity, offers future therapeutic strategy for epilepsy

Study shows asthma mediator IL-13 prevents SARS-CoV-2 infection

Emerging protein-based immunotherapies could lead to highly effective cancer treatments

Scientists establish infection models for SARS-CoV-2 UK & South African variants

Enduring antibody response observed after natural immunity and first Pfizer SARS-CoV-2 vaccine shot

Tier 3 interventions needed to contain SARS-CoV-2 transmission, especially with emergence of variants

School-based cavity prevention program reduces health disparities, brings dental care to children

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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